2005 WGC-American Express Championship

{{use mdy dates|date=October 2018}}

{{Infobox individual golf tournament

| name = 2005 WGC-American Express Championship

| image =

| dates = October 6–9, 2005

| location = San Francisco, California

| course = Harding Park Golf Course

| tour = PGA Tour
European Tour

| par = 70

| yardage = {{convert|7086|yd}}

| field = 71 players

| cut = None

| purse = $7,500,000
€6,144,040

| winners_share = $1,300,000
€1,078,120

| champion = {{flagicon|USA}} Tiger Woods

| score = 270 (−10), playoff

| previous = 2004

| next = 2006

}}

{{Location map

|USA

|relief = 1

|label = Harding Park
Golf Course

|lat = 37.725

|long = -122.493

|caption = Location in the United States

|float =

|background=

|width = 240

}}

The 2005 WGC-American Express Championship was a professional golf tournament held October 6–9 at Harding Park Golf Course in San Francisco, California. It was the sixth WGC-American Express Championship tournament, and the third of three World Golf Championships events held in 2005.

World number 1 Tiger Woods won the tournament to capture his fourth WGC-American Express Championship and his tenth World Golf Championships title. Woods defeated John Daly on the second hole of a playoff when Daly missed a two-foot (0.6 m) putt for par.