2018 San Francisco 49ers season

{{short description|NFL team season}}

{{Use mdy dates|date=August 2023}}

{{Infobox NFL team season

| logo =

| team = San Francisco 49ers

| year = 2018

| record = 4–12

| division_place = 3rd NFC West

| coach = Kyle Shanahan

| off_coach = Kyle Shanahan (de facto)

| def_coach = Robert Saleh

| general manager = John Lynch

| owner = Jed York

| stadium = Levi's Stadium

| playoffs = Did not qualify

| pro bowlers = FB Kyle Juszczyk
TE George Kittle
DT DeForest Buckner

| AP All-pros = George Kittle (2nd team)

| uniform = File:49ers uniforms 18.png

| shortnavlink = 49ers seasons

}}

The 2018 season was the San Francisco 49ers' 69th in the National Football League (NFL), their 73rd overall, their fifth playing their home games at Levi's Stadium and their second under the head coach/general manager tandem of Kyle Shanahan and John Lynch.

After finishing 6–10 from an 0–9 start the previous year, the 49ers were looking to improve from that record and make the playoffs for the first time since 2013. However, the 49ers' season ended with a record of 4–12 and were plagued by multiple season-ending injuries, including running back Jerick McKinnon tearing his ACL in training camp and quarterback Jimmy Garoppolo tearing his ACL in Week 3 against the Kansas City Chiefs. The 49ers were eliminated from playoff contention following a Week 13 loss to the Seattle Seahawks. In Week 15, however, the 49ers upset the Seahawks 26–23 in overtime at home, snapping the 49ers' 10–game losing streak to them that dated back to the 2013 NFC Championship Game. The win also stopped the Seahawks from clinching a playoff spot that week. The 49ers failed to improve on their 6–10 record from last year. The 49ers also went 0–8 on the road for the first time since 1979.

The 49ers defense would also go on to set multiple NFL records for futility. During the entire 16 game schedule of the 2018 NFL season, the 49ers defense would accumulate just two interceptions, breaking the previous mark of three. Incredibly, that included strike shortened NFL seasons. Putting that into perspective, a total of 40 different players throughout the league would go on to have more interceptions than the entire 49ers team. The 49ers would also have just seven total takeaways on the season, smashing the previous record of 11.{{cite web | last=Madson | first=Kyle | title=49ers defense sets NFL record for fewest turnovers in a season | website=Niners Wire|publisher=USA Today | date=2018-12-30 | url=https://ninerswire.usatoday.com/2018/12/30/49ers-defense-sets-nfl-record-for-fewest-turnovers-in-a-season/ | access-date=2024-12-11}}{{cite web|title=49ers report card: Grades for offense, defense in disappointing 2018 season|url=https://www.nbcsports.com/bayarea/49ers/49ers-report-card-grades-offense-defense-disappointing-2018-season|date=December 31, 2018|access-date=December 31, 2018}} The 49ers were also last in the league with a −25 turnover differential, the worst mark since 2008.

The 2018 49ers would go on to set one more notable "futility" mark after the team went 8–0 to start the following season, thus giving the 2018 49ers the worst record in NFL history of any team that went on to go undefeated that far into the following season.

{{TOC limit|3}}

Offseason

=Roster changes=

==Free agency==

The 49ers entered free agency with the following:{{cite web|title=49ers UFA|url=http://www.spotrac.com/nfl/free-agents/all/san-francisco-49ers/|work=Spotrac|access-date=February 8, 2018}}

class="sortable wikitable" style="text-align:center"
style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Position

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Player

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Free agency
tag

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Date signed

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| 2018 Team

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Notes

style="background:#fbb"

| DE

Cornellius CarradineUFAMarch 17, 2018Oakland Raiders{{cite web|title=Raiders Sign Defensive Lineman Tank Carradine|url=http://www.raiders.com/news/article-1/Raiders-Sign-Defensive-Lineman-Tank-Carradine/202880ac-a1f9-4e03-a1ff-bd617d97f009|work=Raiders.com|date=March 17, 2018|access-date=March 24, 2018|archive-url=https://web.archive.org/web/20180321212544/http://www.raiders.com/news/article-1/Raiders-Sign-Defensive-Lineman-Tank-Carradine/202880ac-a1f9-4e03-a1ff-bd617d97f009|archive-date=March 21, 2018|url-status=dead}}
style="background:#bfb"

| OT

Garry GilliamUFAFebruary 27, 2018San Francisco 49ersSigned 2-year contract{{cite web|title=49ers Sign OL Garry Gilliam to a Two-year Contract Extension|url=http://www.49ers.com/news/article-2/49ers-Sign-OL-Garry-Gilliam-to-a-Two-year-Contract-Extension/cb78942d-86b7-4ffd-b8ee-b65515c17257|publisher=49ers.com|access-date=February 27, 2018|archive-url=https://web.archive.org/web/20180228100751/http://www.49ers.com/news/article-2/49ers-Sign-OL-Garry-Gilliam-to-a-Two-year-Contract-Extension/cb78942d-86b7-4ffd-b8ee-b65515c17257|archive-date=February 28, 2018|url-status=dead|df=mdy-all}}{{cite web|last1=Hagemann|first1=Andie|title=Niners sign OL Garry Gilliam to two-year extension|url=https://www.nfl.com/news/niners-sign-ol-garry-gilliam-to-two-year-extension-0ap3000000917809|publisher=NFL.com|access-date=February 27, 2018}}
style="background:#fbb"

| SS

Eric ReidUFASeptember 27, 2018Carolina PanthersSigned 1-year contract{{cite web|title=Panthers sign Eric Reid to one-year contract|url=https://www.panthers.com/news/panthers-sign-eric-reid-to-one-year-contract|publisher=Panthers.com|date=September 27, 2018|access-date=January 3, 2019}}
style="background:#bfb"

| C

Daniel KilgoreUFAFebruary 14, 2018San Francisco 49ersSigned 3-year contract{{cite web|title=49ers Sign C Daniel Kilgore to a Three-year Contract Extension|url=http://www.49ers.com/news/article-2/49ers-Sign-C-Daniel-Kilgore-to-a-Three-year-Contract-Extension/0b3ec2bf-2ec2-4da1-87f8-0726217c544a|publisher=49ers.com|access-date=February 14, 2018}}{{cite web|last1=Wesseling|first1=Chris|title=Niners center Daniel Kilgore signs 3-year extension|url=https://www.nfl.com/news/niners-center-daniel-kilgore-signs-3-year-extension-0ap3000000916253|publisher=NFL.com|access-date=February 14, 2018}}
style="background:#bfb"

| ILB

Brock CoyleUFAMarch 14, 2018San Francisco 49ersSigned 3-year contract{{cite web|title=49ers Agree to Terms with LB Brock Coyle|url=http://www.49ers.com/news/article-2/49ers-Agree-to-Terms-with-LB-Brock-Coyle/eb716849-cc38-4295-a810-70c98fe4b7bd|publisher=49ers.com|access-date=March 14, 2018|archive-url=https://web.archive.org/web/20180315134417/http://www.49ers.com/news/article-2/49ers-Agree-to-Terms-with-LB-Brock-Coyle/eb716849-cc38-4295-a810-70c98fe4b7bd|archive-date=March 15, 2018|url-status=dead}}
style="background:#fbb"

| G

Brandon FuscoUFAMarch 14, 2018Atlanta FalconsSigned 3-year contract{{cite web|title=FALCONS AGREE TO TERMS WITH FORMER 49ERS LINEMAN BRANDON FUSCO ON THREE-YEAR CONTRACT|url=http://www.atlantafalcons.com/news/transactions/article-1/Falcons-agree-to-terms-with-former-49ers-lineman-Brandon-Fusco-on-three-year-contract/b41d23e1-ef0b-431d-9033-da2370993385|publisher=atlantafalcons.com|access-date=March 14, 2018|archive-url=https://web.archive.org/web/20180315011530/http://www.atlantafalcons.com/news/transactions/article-1/Falcons-agree-to-terms-with-former-49ers-lineman-Brandon-Fusco-on-three-year-contract/b41d23e1-ef0b-431d-9033-da2370993385|archive-date=March 15, 2018|url-status=dead}}
style="background:#fbb"

| CB

Leon HallUFAMarch 30, 2018Oakland Raiders
style="background:#fbb"

| RB

Carlos HydeUFAMarch 15, 2018Cleveland BrownsSigned 3-year contract{{cite web|last=Maks|first=Patrick|title=Browns sign RB Carlos Hyde as they continue to fortify offense|url=http://www.clevelandbrowns.com/news/article-5/Browns-sign-RB-Carlos-Hyde-as-they-continue-to-fortify-offense%E2%80%8B/1bd211ab-9c2b-44e8-b57d-c00411c46031|work=ClevelandBrowns.com|date=March 15, 2018|access-date=March 20, 2018|archive-url=https://web.archive.org/web/20180321181707/http://www.clevelandbrowns.com/news/article-5/Browns-sign-RB-Carlos-Hyde-as-they-continue-to-fortify-offense%E2%80%8B/1bd211ab-9c2b-44e8-b57d-c00411c46031|archive-date=March 21, 2018|url-status=dead}}
style="background:#bfb"

| OLB

Mark NzeochaUFAJanuary 26, 2018San Francisco 49ersSigned 1-year contract{{cite web|title=49ers Re-Sign LB Nzeocha|url=http://www.49ers.com/news/article-2/49ers-Re-Sign-LB-Nzeocha/689f0014-86fe-4080-8961-d26692f0ac8c|publisher=49ers.com|date=January 26, 2018|access-date=February 8, 2018}}
DTLeger DouzableUFA
WRLouis MurphyUFA
style="background:#bfb"

| QB

Jimmy GaroppoloUFAFebruary 8, 2018San Francisco 49ersSigned 5-year contract{{cite web|title=49ers Sign QB Jimmy Garoppolo to Five-year Extension|url=http://www.49ers.com/news/article-2/49ers-Sign-QB-Jimmy-Garoppolo-to-Five-year-Extension/0f0e08aa-0d42-4849-b97b-55a8d827fb4f|publisher=49ers.com|access-date=February 8, 2018}}{{cite web|last1=Patra|first1=Kevin|title=49ers sign Jimmy Garoppolo to record 5-year deal|url=https://www.nfl.com/news/jimmy-garoppolo-signs-record-5-year-deal-with-49ers-0ap3000000915489|publisher=NFL.com|access-date=February 8, 2018}}
CBAsa JacksonUFA
style="background:#fbb"

| TE

Logan PaulsenUFAMarch 21, 2018Atlanta FalconsSigned 1-year contract{{cite web|title=Falcons agree to terms with former 49ers tight end Logan Paulsen|url=http://www.atlantafalcons.com/news/transactions/article-1/NFL-free-agency-Falcons-agree-to-terms-with-former-49ers-tight-end-Logan-Paulsen/34f1e222-f787-4ed1-a108-a916b42e919c|author=McFadden, Will|website=AtlantaFalcons.com|date=March 21, 2018|access-date=March 24, 2018|archive-url=https://web.archive.org/web/20180504044851/http://www.atlantafalcons.com/news/transactions/article-1/NFL-free-agency-Falcons-agree-to-terms-with-former-49ers-tight-end-Logan-Paulsen/34f1e222-f787-4ed1-a108-a916b42e919c|archive-date=May 4, 2018|url-status=dead|df=mdy-all}}
CTim BarnesUFA
style="background:#bfb"

| FS

Antone ExumUFAJune 6, 2018San Francisco 49ersSigned 1-year contract{{cite web|title=49ers Sign DB Antone Exum Jr.|url=https://www.49ers.com/news/49ers-sign-db-antone-exum-jr?sf191233357=1|publisher=49ers.com|access-date=June 6, 2018}}
style="background:#bfb"

| OLB

Cassius MarshUFAFebruary 7, 2018San Francisco 49ersSigned 2-year contract{{cite web|title=49ers Re-sign DL Cassius Marsh to a Two-year Deal|url=http://www.49ers.com/news/article-2/49ers-Re-sign-DL-Cassius-Marsh-to-a-Two-year-Deal/d4fb86c3-e2af-4eda-8e10-49e0d6a8c935|publisher=49ers.com|date=February 7, 2018|access-date=February 8, 2018}}{{cite web|last1=Lewis|first1=Edward|title=Niners re-sign DL Cassius Marsh to two-year deal|url=http://www.nfl.com/news/story/0ap3000000915310/article/niners-resign-dl-cassius-marsh-to-twoyear-deal|archive-url=https://web.archive.org/web/20180208101810/http://www.nfl.com/news/story/0ap3000000915310/article/niners-resign-dl-cassius-marsh-to-twoyear-deal|url-status=dead|archive-date=February 8, 2018|publisher=NFL.com|date=February 7, 2018|access-date=February 8, 2018}}
style="background:#fbb"

| CB

Dontae JohnsonUFAApril 11, 2018Seattle Seahawks{{cite web|title=Seahawks Sign Cornerback Dontae Johnson|url=https://www.seahawks.com/news/seahawks-sign-cornerback-dontae-johnson|author=Boyle, John|website=Seahawks.com|date=April 11, 2018}}
style="background:#fbb"

| DE

Aaron LynchUFAMarch 15, 2018Chicago BearsSigned 1-year contract{{cite web|title=Chicago Bears sign Aaron Lynch|url=https://www.windycitygridiron.com/2018/3/15/17127372/chicago-bears-sign-aaron-lynch-free-agency-san-francisco-49ers-nfl-outside-linebacker-vic-fangio|website=WindyCityGridiron.com|date=March 15, 2018|access-date=March 24, 2018}}{{cite web|url=http://www.chicagobears.com/news/article-rostermoves/Bears-bolster-defense-by-signing-Lynch/35ed6945-c6cd-4171-8ce9-6b7facea0c92|title=Bears bolster defense by signing Lynch|work=ChicagoBears.com|first=Larry|last=Mayer|date=March 15, 2018|access-date=March 24, 2018}}
style="background:#bfb"

| RB

Raheem MostertRFAMarch 9, 2018San Francisco 49ersSigned 1-year contract{{cite web|title=49ers Announce a Pair of Roster Moves|url=http://www.49ers.com/news/article-2/49ers-Announce-a-Pair-of-Roster-Moves/c22fd2b8-acae-452c-ae4e-276a1685a4da?sf184318572=1|publisher=49ers.com|date=March 12, 2018|access-date=March 12, 2018|archive-url=https://web.archive.org/web/20180313092202/http://www.49ers.com/news/article-2/49ers-Announce-a-Pair-of-Roster-Moves/c22fd2b8-acae-452c-ae4e-276a1685a4da?sf184318572=1|archive-date=March 13, 2018|url-status=dead}}
colspan="6"|RFA: Restricted free agent, UFA: Unrestricted free agent, ERFA: Exclusive rights free agent

;LEGEND

:{{color box|#bfb|–|black}} Light green background indicates a player has been re-signed by the 49ers.

:{{color box|#fbb|–|black}} Light red background indicates a player has departed the 49ers.

==Signings==

class="sortable wikitable" style="text-align:center"

|+

style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Position

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Player

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| 2017 Team

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Date signed

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Notes

style="background:#ff9"

| CB

Richard ShermanSeattle SeahawksMarch 11, 2018Signed 3-year contract{{cite web|title=49ers Sign CB Richard Sherman|url=http://www.49ers.com/news/article-2/49ers-Sign-CB-Richard-Sherman/0563a9d0-bb31-4363-9ac1-eb3f07ba979d|website=49ers.com|date=March 11, 2018|access-date=March 12, 2018|archive-url=https://web.archive.org/web/20180312020046/http://www.49ers.com/news/article-2/49ers-Sign-CB-Richard-Sherman/0563a9d0-bb31-4363-9ac1-eb3f07ba979d|archive-date=March 12, 2018|url-status=dead}}{{cite web|last=Shook|first=Nick|title=Richard Sherman joining 49ers on 3-year, $39M deal|url=http://www.nfl.com/news/story/0ap3000000920544/article/richard-sherman-joining-49ers-on-3year-39m-deal|archive-url=https://web.archive.org/web/20180311035615/http://www.nfl.com/news/story/0ap3000000920544/article/richard-sherman-joining-49ers-on-3year-39m-deal|url-status=dead|archive-date=March 11, 2018|website=NFL.com|access-date=March 10, 2018}}
PJeff LockeMarch 12, 2018Signed 1-year contract
style="background:#ff9"

| RB

Jerick McKinnonMinnesota VikingsMarch 14, 2018Signed 4-year contract{{cite web|title=49ers Agree to Terms with RB Jerick McKinnon and G/C Weston Richburg|url=http://www.49ers.com/news/article-2/49ers-Agree-to-Terms-with-RB-Jerick-McKinnon-and-GC-Weston-Richburg/936ecc05-4c31-462c-a8ea-f474f56bf907|website=49ers.com|date=March 14, 2018|access-date=March 14, 2018|archive-url=https://web.archive.org/web/20180315041451/http://www.49ers.com/news/article-2/49ers-Agree-to-Terms-with-RB-Jerick-McKinnon-and-GC-Weston-Richburg/936ecc05-4c31-462c-a8ea-f474f56bf907|archive-date=March 15, 2018|url-status=dead}}
style="background:#ff9"

| C

Weston RichburgNew York GiantsMarch 14, 2018Signed 5-year contract
style="background:#ff9"

| DE

Jeremiah AttaochuLos Angeles ChargersMarch 15, 2018Signed 1-year contract{{cite web|title=49ers Sign DL Jeremiah Attaochu|url=http://www.49ers.com/news/article-2/49ers-Sign-DL-Jeremiah-Attaochu/7b1a4fbd-990c-43d6-86fb-0089e9d72c98|website=49ers.com|date=March 15, 2018|access-date=March 18, 2018|archive-url=https://web.archive.org/web/20180318141933/http://www.49ers.com/news/article-2/49ers-Sign-DL-Jeremiah-Attaochu/7b1a4fbd-990c-43d6-86fb-0089e9d72c98|archive-date=March 18, 2018|url-status=dead}}
style="background:#ff9"

| G

Jonathan CooperDallas CowboysMarch 20, 2018Signed 1-year contract{{cite web|title=49ers Sign G Jonathan Cooper|url=http://www.49ers.com/news/article-2/49ers-Sign-G-Jonathan-Cooper/36bc53b5-18fb-42cc-8109-6673e855a745|website=49ers.com|access-date=March 20, 2018|archive-url=https://web.archive.org/web/20180321002607/http://www.49ers.com/news/article-2/49ers-Sign-G-Jonathan-Cooper/36bc53b5-18fb-42cc-8109-6673e855a745|archive-date=March 21, 2018|url-status=dead}}
style="background:#ff9"

| LB

Korey ToomerLos Angeles ChargersApril 4, 2018Signed 1-year contract{{cite web|title=49ers Sign LB Toomer|url=https://www.49ers.com/news/49ers-sign-lb-toomer?sf186254147=1|website=49ers.com|access-date=April 4, 2018}}
style="background:#ff9"

| G

Mike PersonIndianapolis ColtsMay 9, 2018Signed 1-year contract{{cite web|title=49ers Sign OL Mike Person|url=https://www.49ers.com/news/49ers-sign-ol-mike-person|website=49ers.com|date=May 9, 2018|access-date=August 28, 2018}}
CBC. J. GoodwinNew York GiantsMay 15, 2018Claimed off waivers{{cite web|title=49ers Announce a Pair of Roster Moves|url=https://www.49ers.com/news/49ers-announce-a-pair-of-roster-moves|website=49ers.com|date=May 15, 2018|access-date=August 28, 2018}}
GJohn FlynnJuly 25, 2018Signed 2-year contract{{cite web|title=49ers Announce Several Roster Moves|url=http://www.49ers.com/news/article-2/49ers-Sign-CB-Will-Davis/8055c28a-2a21-4469-905a-e24f00a4a729|website=49ers.com|date=July 25, 2018|access-date=September 6, 2018}}
DTWill SuttonJuly 25, 2018Signed 1-year contract
style="background:#ff9"

| DT

Cedric ThorntonBuffalo BillsJuly 25, 2018Signed 1-year contract
TEWes SaxtonJuly 31, 2018Signed 1-year contract{{cite web|title=49ers Sign TE Wes Saxton|url=https://www.49ers.com/news/49ers-sign-te-wes-saxton|website=49ers.com|date=July 31, 2018|access-date=September 1, 2018}}
style="background:#ff9"

| G

Chris GonzalezAugust 5, 2018Signed 1-year contract{{cite web|title=49ers Sign G Chris Gonzalez, Waive Griffin|url=https://www.49ers.com/news/49ers-sign-g-chris-gonzalez|website=49ers.com|date=August 5, 2018|access-date=September 6, 2018}}
style="background:#ff9"

| RB

Alfred MorrisDallas CowboysAugust 14, 2018Signed 1-year contract{{cite web|title=49ers Sign RB Alfred Morris; Waive OL Alan Knott|url=https://www.49ers.com/news/49ers-sign-rb-morris-waive-ol-knott|website=49ers.com|date=August 14, 2018|access-date=September 1, 2018}}

style="background:#ff9; border:1px solid #aaa; width:2em"|

| Indicates that the player was a free agent at the end of his respective team's {{nfly|2017}} season.

==Departures==

class="sortable wikitable" style="text-align:center"
style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Position

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Player

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Date

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Notes

CDaniel KilgoreMarch 15, 2018Traded{{cite web|title=49ers Trade C Daniel Kilgore to the Dolphins|url=http://www.49ers.com/news/article-2/49ers-Trade-C-Daniel-Kilgore-to-the-Dolphins/424775c4-9d20-45d7-89dc-c9dbf73dfef8|website=49ers.com|date=March 15, 2018|access-date=March 19, 2018|archive-url=https://web.archive.org/web/20180319151748/http://www.49ers.com/news/article-2/49ers-Trade-C-Daniel-Kilgore-to-the-Dolphins/424775c4-9d20-45d7-89dc-c9dbf73dfef8|archive-date=March 19, 2018|url-status=dead}}
TTrent BrownApril 27, 2018Traded{{cite web|last1=Sessler|first1=Marc|title=Trent Brown traded by 49ers to New England Patriots|url=https://www.nfl.com/news/trent-brown-traded-by-49ers-to-new-england-patriots-0ap3000000929371|website=NFL.com|date=April 27, 2018|access-date=April 27, 2018}}
GZane BeadlesMay 7, 2018Released{{cite web|title=49ers Release G Zane Beadles|url=https://www.49ers.com/news/49ers-release-g-zane-beadles|website=49ers.com|access-date=May 7, 2018}}
WRDeAndre CarterMay 15, 2018Waived
SDon JonesJuly 25, 2018Waived
CBC. J. GoodwinJuly 31, 2018Waived
LBEli HaroldAugust 23, 2018Traded{{cite web|title=49ers Trade LB Eli Harold|url=https://www.49ers.com/news/49ers-trade-lb-eli-harold|website=49ers.com|date=August 23, 2018|access-date=August 27, 2018}}{{cite web|last1=Sessler|first1=Marc|title=Trade! Lions acquire LB Eli Harold from 49ers|url=https://www.nfl.com/news/trade-lions-acquire-lb-eli-harold-from-49ers-0ap3000000950252|website=NFL.com|date=August 23, 2018|access-date=August 27, 2018}}

Draft

{{main|2018 NFL draft}}

class="wikitable" style="text-align:center"

|+ style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| 2018 San Francisco 49ers Draft

style="{{NFLAltPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Roundstyle="{{NFLAltPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Selectionstyle="{{NFLAltPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Playerstyle="{{NFLAltPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Positionstyle="{{NFLAltPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Collegestyle="{{NFLAltPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Notes
1 || 9

| Mike McGlinchey || OT || Notre Dame ||

2 || 44

| Dante Pettis || WR || Washington || {{small|from Washington}}

rowspan="2" | 3 || 70

| Fred Warner || LB || BYU || {{small|from Chicago}}

95

| Tarvarius Moore || S || Southern Miss || {{small|from New England}}

4 || 128

| Kentavius Street || DE || NC State || {{small|from Pittsburgh}}

5 || 142

| D. J. Reed || CB || Kansas State || {{small|from Denver via Washington}}

6 || 184

| Marcell Harris || S || Florida ||

rowspan="2" | 7 || 233

| Jullian Taylor || DT || Temple || {{small|from Tampa Bay via Miami}}

240

| Richie James || WR || Middle Tennessee || {{small|from Kansas City}}

Notes

  • The 49ers finished with the same overall record and strength of schedule as the Oakland Raiders at the end of the {{nfly|2017}} season, and their selecting order was determined by way of a coin flip at the NFL Scouting Combine in early 2018. Both teams will then rotate with the Miami Dolphins, selecting 9th, 10th and 11th in each round. The 49ers won the coin toss.{{cite web | url=http://www.49ers.com/video/videos/49ers_Win_Coin_Toss_Over_Raiders_for_Ninthoverall_Pick/c2e85f80-9384-4856-8592-05d3b4026993 | title=49ers win coin toss | access-date=March 2, 2018 }}{{Dead link|date=June 2020 |bot=InternetArchiveBot |fix-attempted=yes }}

Draft trades

  • The 49ers traded a second-round selection (43rd overall) to New England in exchange for quarterback Jimmy Garoppolo.
  • The 49ers traded their third-round selection in 2017 (67th overall) to New Orleans in exchange for New Orleans' second-round selection (59th overall) and their seventh-round selection in 2017 (229th overall).
  • The 49ers traded their first-round selection in 2017 (2nd overall) to Chicago in exchange for Chicago's third-round selection (70th overall), and their first-, third- and fourth-round selections in 2017 (3rd, 67th and 111th overall).
  • The 49ers traded their fourth-round selection (109th overall) to Denver in exchange for Denver's fifth-round selection in 2017 (177th overall) and running back Kapri Bibbs.
  • The 49ers traded their fifth-round selection (148th overall) and tight end Vance McDonald to Pittsburgh in exchange for Pittsburgh's fourth-round selection (128th overall).
  • The 49ers traded cornerback Rashard Robinson to the New York Jets in exchange for the Jets' fifth-round selection (143rd overall).
  • The 49ers traded their seventh-round selection (227th overall) and center Daniel Kilgore to Miami in exchange for the seventh-round selection Miami acquired from Tampa Bay (223rd overall).{{cite web|last=Wesseling|first=Chris|title=Trade! Dolphins replacing Pouncey with 49ers' Kilgore|url=https://www.nfl.com/news/trade-dolphins-replacing-pouncey-with-49ers-kilgore-0ap3000000921489|website=NFL.com|date=March 15, 2018|access-date=March 19, 2018}}
  • The 49ers traded cornerback Kenneth Acker to Kansas City in exchange for Kansas City's seventh-round selection (240th overall).
  • The 49ers traded their fifth-round selection (143rd overall) and OT Trent Brown to New England in exchange for the third-round selection (95th overall).{{cite web|title=49ers Trade Trent Brown to Patriots of 2018 Third-round Pick|url=https://www.49ers.com/news/49ers-trade-trent-brown-to-patriots-of-2018-third-round-pick?sf187990818=1&sf187993814=1|website=NFL.com|access-date=April 27, 2018}}

=Undrafted free agents=

class="wikitable" style="text-align:center"

|+ style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| 2018 San Francisco 49ers Undrafted Free Agents

style="{{NFLAltPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Position

! style="{{NFLAltPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Player

! style="{{NFLAltPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| College

! style="{{NFLAltPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Notes

WRSteven DunbarHouston
TERoss DwelleySan Diego
QBJack HeneghanDartmouth
OLAlan KnottSouth CarolinaWaived August 14
OTJamar McGlosterSyracuseWaived July 25
DLZach FranklinFrostburg State
STerrell WilliamsHouston
SCorey GriffinGeorgia TechWaived August 5
CBTarvarus McFaddenFlorida State
CBEmmanuel MoseleyTennessee
OLNajee ToranUCLA
OLColeman SheltonWashington
RBJeff WilsonNorth Texas
DLBlaine WoodsonDelawareWaived July 25

Staff

{{NFL final staff

|Year=2018

|TeamName=San Francisco 49ers

|Front Office=

|Head Coaches=

|Offensive Coaches=

|Defensive Coaches=

|Special Teams Coaches=

|Strength and Conditioning=

  • Head strength and conditioning – Ray Wright
  • Strength and conditioning assistant – Marquis Johnson
  • Strength and conditioning assistant – Dustin Perry

}}

Final roster

{{NFL final roster

|Year=2018

|TeamName=San Francisco 49ers

|Active=53

|Inactive=16

|PS=6

|Quarterbacks=

{{NFLplayer| 3|C. J. Beathard}}

{{NFLplayer| 4|Nick Mullens}}

|Running Backs=

{{NFLplayer|43|Matthew Dayes}}

{{NFLplayer|44|Kyle Juszczyk|FB}}

{{NFLplayer|46|Alfred Morris|d=American football}}

{{NFLplayer|41|Jeff Wilson|d=American football|rookie=y}}

|Wide Receivers=

{{NFLplayer|84|Kendrick Bourne}}

{{NFLplayer|19|Steven Dunbar|rookie=y}}

{{NFLplayer|11|Marquise Goodwin}}

{{NFLplayer|13|Richie James|rookie=y}}

{{NFLplayer|14|Max McCaffrey}}

{{NFLplayer|81|Trent Taylor}}

|Tight Ends=

{{NFLplayer|88|Garrett Celek}}

{{NFLplayer|82|Ross Dwelley|rookie=y}}

{{NFLplayer|85|George Kittle}}

|Offensive Linemen=

{{NFLplayer|78|Shon Coleman|T}}

{{NFLplayer|65|Joshua Garnett|G}}

{{NFLplayer|76|Garry Gilliam|T}}

{{NFLplayer|62|Erik Magnuson|C}}

{{NFLplayer|69|Mike McGlinchey|d=offensive lineman|rookie=y|T}}

{{NFLplayer|68|Mike Person|G}}

{{NFLplayer|58|Weston Richburg|C}}

{{NFLplayer|74|Joe Staley|T}}

{{NFLplayer|75|Laken Tomlinson|G}}

|Defensive Linemen=

{{NFLplayer|91|Arik Armstead|DE}}

{{NFLplayer|98|Ronald Blair|DE}}

{{NFLplayer|99|DeForest Buckner|DT}}

{{NFLplayer|96|Sheldon Day|DT}}

{{NFLplayer|92|Ryan Delaire|DE}}

{{NFLplayer|93|D. J. Jones|d=defensive lineman|DT}}

{{NFLplayer|54|Cassius Marsh|DE}}

{{NFLplayer|90|Earl Mitchell|DT}}

{{NFLplayer|77|Jullian Taylor|rookie=y|DT}}

{{NFLplayer|94|Solomon Thomas|DE}}

|Linebackers=

{{NFLplayer|47|Elijah Lee|OLB}}

{{NFLplayer|53|Mark Nzeocha|OLB}}

{{NFLplayer|57|James Onwualu|MLB}}

{{NFLplayer|51|Malcolm Smith|d=American football|OLB}}

{{NFLplayer|55|Pita Taumoepenu|OLB}}

{{NFLplayer|48|Fred Warner|d=American football|MLB|rookie=y}}

|Defensive Backs=

{{NFLplayer|38|Antone Exum|SS}}

{{NFLplayer|36|Marcell Harris|rookie=y|SS}}

{{NFLplayer|35|Godwin Igwebuike|rookie=y|FS}}

{{NFLplayer|26|Greg Mabin|CB}}

{{NFLplayer|33|Tarvarius Moore|rookie=y|CB/FS}}

{{NFLplayer|30|Tyvis Powell|SS}}

{{NFLplayer|32|D. J. Reed|rookie=y|FS/CB}}

{{NFLplayer|49|Tyree Robinson|rookie=y|FS}}

{{NFLplayer|25|Richard Sherman|d=American football|CB}}

{{NFLplayer|24|K'Waun Williams|CB}}

|Special Teams=

{{NFLplayer| 9|Robbie Gould|K}}

{{NFLplayer|40|Colin Holba|LS}}

{{NFLplayer| 5|Bradley Pinion|P}}

|Reserve Lists=

{{NFLplayer|22|Matt Breida|RB|IR}}

{{NFLplayer|27|Adrian Colbert|FS|IR}}

{{NFLplayer|50|Brock Coyle|OLB|IR}}

{{NFLplayer|60|JP Flynn|C/G|IR}}

{{NFLplayer|15|Pierre Garçon|WR|IR}}

{{NFLplayer|10|Jimmy Garoppolo|QB|IR}}

{{NFLplayer|28|Jerick McKinnon|RB|IR}}

{{NFLplayer|41|Emmanuel Moseley|rookie=y|CB|IR}}

{{NFLplayer|31|Raheem Mostert|RB|IR}}

{{NFLplayer|86|Kyle Nelson|d=American football|LS|Susp.}}

{{NFLplayer|18|Dante Pettis|rookie=y|WR|IR}}

{{NFLplayer|95|Kentavius Street|rookie=y|DE|NF-Inj.}}

{{NFLplayer|29|Jaquiski Tartt|SS|IR}}

{{NFLplayer|20|Jimmie Ward|CB/FS|IR}}

{{NFLplayer|97|Dekoda Watson|OLB|IR}}

{{NFLplayer|23|Ahkello Witherspoon|CB|IR}}

|Practice Squad=

{{NFLplayer|64|Christian DiLauro|rookie=y|T}}

{{NFLplayer|83|Marcus Lucas|TE}}

{{NFLplayer|45|Tarvarus McFadden|CB|rookie=y}}

{{NFLplayer|17|Jordan Smallwood|d=American football|WR|rookie=y}}

{{NFLplayer|66|Najee Toran|G|rookie=y}}

{{NFLplayer| 6|Terrell Williams|d=defensive back|FS|rookie=y}}

}}

Preseason

class="wikitable" style="text-align:center"

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Week

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Date

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Opponent

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Result

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Record

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Venue

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Recap

style="background:#cfc"

! 1

| {{dow tooltip|August 9, 2018}}

| Dallas Cowboys

| W 24–21

| 1–0

| Levi's Stadium

| [http://www.nfl.com/gamecenter/2018080961/2018/PRE1/cowboys@49ers Recap]

style="background:#fcc"

! 2

| {{dow tooltip|August 18, 2018}}

| at Houston Texans

| L 13–16

| 1–1

| NRG Stadium

| [http://www.nfl.com/gamecenter/2018081853/2018/PRE2/49ers@texans Recap]

style="background:#fcc"

! 3

| {{dow tooltip|August 25, 2018}}

| at Indianapolis Colts

| L 17–23

| 1–2

| Lucas Oil Stadium

| [http://www.nfl.com/gamecenter/2018082552/2018/PRE3/49ers@colts Recap]

style="background:#fcc"

! 4

| {{dow tooltip|August 30, 2018}}

| Los Angeles Chargers

| L 21–23

| 1–3

| Levi's Stadium

| [http://www.nfl.com/gamecenter/2018083063/2018/PRE4/chargers@49ers Recap]

Regular season

=Schedule=

class="wikitable" style="text-align:center"

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Week

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Date

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Opponent

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Result

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Record

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Venue

! style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"| Recap

style="background:#fcc"

! 1

| September 9

| at Minnesota Vikings

| L 16–24

| 0–1

| U.S. Bank Stadium

| [http://www.nfl.com/gamecenter/2018090904/2018/REG1/49ers@vikings Recap]

style="background:#cfc"

! 2

| September 16

| Detroit Lions

| W 30–27

| 1–1

| Levi's Stadium

| [http://www.nfl.com/gamecenter/2018091610/2018/REG2/lions@49ers Recap]

style="background:#fcc"

! 3

| September 23

| at Kansas City Chiefs

| L 27–38

| 1–2

| Arrowhead Stadium

| [http://www.nfl.com/gamecenter/2018092305/2018/REG3/49ers@chiefs Recap]

style="background:#fcc"

! 4

| September 30

| at Los Angeles Chargers

| L 27–29

| 1–3

| StubHub Center

| [http://www.nfl.com/gamecenter/2018093010/2018/REG4/49ers@chargers Recap]

style="background:#fcc"

! 5

| October 7

| Arizona Cardinals

| L 18–28

| 1–4

| Levi's Stadium

| [http://www.nfl.com/gamecenter/2018100710/2018/REG5/cardinals@49ers Recap]

style="background:#fcc"

! 6

| {{dow tooltip|October 15, 2018}}

| at Green Bay Packers

| L 30–33

| 1–5

| Lambeau Field

| [http://www.nfl.com/gamecenter/2018101500/2018/REG6/49ers@packers Recap]

style="background:#fcc"

! 7

| October 21

| Los Angeles Rams

| L 10–39

| 1–6

| Levi's Stadium

| [http://www.nfl.com/gamecenter/2018102111/2018/REG7/rams@49ers Recap]

style="background:#fcc"

! 8

| October 28

| at Arizona Cardinals

| L 15–18

| 1–7

| State Farm Stadium

| [http://www.nfl.com/gamecenter/2018102809/2018/REG8/49ers@cardinals Recap]

style="background:#cfc"

! 9

| {{dow tooltip|November 1, 2018}}

| Oakland Raiders

| W 34–3

| 2–7

| Levi's Stadium

| [http://www.nfl.com/gamecenter/2018110100/2018/REG9/raiders@49ers Recap]

style="background:#fcc"

! 10

| {{dow tooltip|November 12, 2018}}

| New York Giants

| L 23–27

| 2–8

| Levi's Stadium

| [http://www.nfl.com/gamecenter/2018111200/2018/REG10/giants@49ers Recap]

11

| colspan="6" |Bye

style="background:#fcc"

! 12

| November 25

| at Tampa Bay Buccaneers

| L 9–27

| 2–9

| Raymond James Stadium

| [http://www.nfl.com/gamecenter/2018112507/2018/REG12/49ers@buccaneers Recap]

style="background:#fcc"

! 13

| December 2

| at Seattle Seahawks

| L 16–43

| 2–10

| CenturyLink Field

| [http://www.nfl.com/gamecenter/2018120213/2018/REG13/49ers@seahawks Recap]

style="background:#cfc"

! 14

| December 9

| Denver Broncos

| W 20–14

| 3–10

| Levi's Stadium

| [http://www.nfl.com/gamecenter/2018120910/2018/REG14/broncos@49ers Recap]

style="background:#cfc"

! 15

| December 16

| Seattle Seahawks

| W 26–23 {{small|(OT)}}

| 4–10

| Levi's Stadium

| [http://www.nfl.com/gamecenter/2018121609/2018/REG15/seahawks@49ers Recap]

style="background:#fcc"

! 16

| December 23

| Chicago Bears

| L 9–14

| 4–11

| Levi's Stadium

| [http://www.nfl.com/gamecenter/2018122312/2018/REG16/bears@49ers Recap]

style="background:#fcc"

! 17

| December 30

| at Los Angeles Rams

| L 32–48

| 4–12

| Los Angeles Memorial Coliseum

| [http://www.nfl.com/gamecenter/2018123014/2018/REG17/49ers@rams Recap]

style="{{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}}"

|colspan="8"| Note: Intra-division opponents are in bold text.

=Game summaries=

==Week 1: at Minnesota Vikings==

{{Americanfootballbox

|titlestyle={{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}};text-align:center;

|state=autocollapse

|title=Week One: San Francisco 49ers at Minnesota Vikings – Game summary

|date=September 9

|time=12:00 p.m. CDT/10:00 a.m. PDT

|road=49ers

|R1=0|R2=3|R3=10|R4=3

|home=Vikings

|H1=3|H2=7|H3=14|H4=0

|stadium=U.S. Bank Stadium, Minneapolis, Minnesota

|attendance=66,673

|weather=Played indoors (dome stadium)

|referee=Clay Martin

|TV=Fox

|TVAnnouncers=Kevin Burkhardt, Charles Davis and Pam Oliver

|reference=[http://www.nfl.com/gamecenter/2018090904/2018/REG1/49ers@vikings Recap]

|scoring=

First quarter

  • MIN – Daniel Carlson 48-yard field goal, 3:56. Vikings 3–0. Drive: 7 plays, 40 yards, 3:21.

Second quarter

  • MIN – Stefon Diggs 22-yard pass from Kirk Cousins (Daniel Carlson kick), 13:39. Vikings 10–0. Drive: 6 plays, 53 yards, 2:32.
  • SF – Robbie Gould 42-yard field goal, 11:42. Vikings 10–3. Drive: 7 plays, 51 yards, 1:57.

Third quarter

  • MIN – Mike Hughes 28-yard interception return (Daniel Carlson kick), 10:41. Vikings 17–3.
  • SF – Robbie Gould 33-yard field goal, 9:15. Vikings 17–6. Drive: 5 plays, 60 yards, 1:26.
  • MIN – Kyle Rudolph 11-yard pass from Kirk Cousins (Daniel Carlson kick), 4:22. Vikings 24–6. Drive: 9 plays, 75 yards, 4:53.
  • SF – Dante Pettis 22-yard pass from Jimmy Garoppolo (Robbie Gould kick), 0:31. Vikings 24–13. Drive: 7 plays, 75 yards, 3:51.

Fourth quarter

  • SF – Robbie Gould 22-yard field goal, 8:09. Vikings 24–16. Drive: 11 plays, 82 yards, 5:34.

|stats=

Top passers

Top rushers

Top receivers

}}

Three interceptions by Jimmy Garoppolo, who earned his first loss as an NFL starter, would hurt the 49ers in the end. The 49ers lost 24–16, with the difference being a Garoppolo pick-six as well several key drops by receivers. With the Loss, the 49ers started their season 0-1 for the second consecutive season.

==Week 2: vs. Detroit Lions==

{{Americanfootballbox

|titlestyle={{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}};text-align:center;

|state=autocollapse

|title=Week Two: Detroit Lions at San Francisco 49ers – Game summary

|date=September 16

|time=1:05 pm. PDT

|road=Lions

|R1=7|R2=3|R3=3|R4=14

|home=49ers

|H1=3|H2=10|H3=14|H4=3

|stadium=Levi's Stadium, Santa Clara, California

|attendance=70,164

|weather={{convert|73|F|C}}, clear

|referee=Shawn Hochuli

|TV=Fox

|TVAnnouncers=Thom Brennaman, Chris Spielman and Shannon Spake

|reference=[http://www.nfl.com/gamecenter/2018091610/2018/REG2/lions@49ers Recap]

|scoring=

First quarter

Second quarter

  • SF – Kendrick Bourne 4-yard pass from Jimmy Garoppolo (Robbie Gould kick), 12:07. 49ers 10–7. Drive: 13 plays, 88 yards, 5:38.
  • SF – Robbie Gould 42-yard field goal, 4:55. 49ers 13–7. Drive: 4 plays, -8 yards, 1:35.
  • DET – Matt Prater 27-yard field goal, 0:03. 49ers 13–10. Drive: 9 plays, 57 yards, 0:46.

Third quarter

  • SF – Garrett Celek 11-yard pass from Jimmy Garoppolo (Robbie Gould kick), 13:17. 49ers 20–10. Drive: 4 plays, 26 yards, 1:43.
  • DET – Matt Prater 43-yard field goal, 8:46. 49ers 20–13. Drive: 8 plays, 27 yards, 4:31.
  • SF – Matt Breida 66-yard run (Robbie Gould kick), 0:52. 49ers 27–13. Drive: 3 plays, 97 yards, 1:13.

Fourth quarter

  • SF – Robbie Gould 36-yard field goal, 11:21. 49ers 30–13. Drive: 7 plays, 35 yards, 3:22.
  • DET – Marvin Jones 5-yard pass from Matthew Stafford (Matt Prater kick), 8:36. 49ers 30–20. Drive: 5 plays, 80 yards, 2:45.
  • DET - Michael Roberts 15-yard pass from Matthew Stafford (Matt Prater kick), 3:27. 49ers 30–27. Drive: 12 plays, 79 yards, 2:41.

|stats=

Top passers

Top rushers

Top receivers

}} Despite the Lions' attempted comeback in the fourth quarter, the 49ers would hang on to win 30-27 as the team earns their first win of the season behind 2 TDs from Garoppolo and Matt Breida's 138 yards rushing. With the win, the 49ers evened their record to 1-1

==Week 3: at Kansas City Chiefs==

{{Americanfootballbox

|titlestyle={{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}};text-align:center;

|state=autocollapse

|title=Week Three: San Francisco 49ers at Kansas City Chiefs – Game summary

|date=September 23

|time=12:00 pm. CDT/10:00 am. PDT

|road=49ers

|R1=0|R2=10|R3=14|R4=3

|home=Chiefs

|H1=14|H2=21|H3=0|H4=3

|stadium=Arrowhead Stadium, Kansas City, Missouri

|attendance=76,023

|weather={{convert|70|F|C}}, clear and sunny

|referee=Tony Corrente

|TV=Fox

|TVAnnouncers=Thom Brennaman, Chris Spielman and Shannon Spake

|reference=[http://www.nfl.com/gamecenter/2018092305/2018/REG3/49ers@chiefs Recap]

|scoring=

First quarter

  • KC – Kareem Hunt 1-yard run (Harrison Butker kick), 8:24. Chiefs 7–0. Drive: 11 plays, 57 yards, 4:55.
  • KC – Kareem Hunt 1-yard run (Harrison Butker kick), 2:20. Chiefs 14–0. Drive: 8 plays, 84 yards, 3:26.

Second quarter

  • SF – Kyle Juszczyk 35-yard pass from Jimmy Garoppolo (Robbie Gould kick), 11:52. Chiefs 14–7. Drive: 8 plays, 75 yards, 5:28.
  • KC – Chris Conley 4-yard pass from Patrick Mahomes (Harrison Butker kick), 8:54. Chiefs 21–7. Drive: 5 plays, 75 yards, 2:58.
  • KC – Demetrius Harris 13-yard pass from Patrick Mahomes (Harrison Butker kick), 3:37. Chiefs 28–7. Drive: 8 plays, 72 yards, 3:35.
  • KC – Sammy Watkins 12-yard pass from Patrick Mahomes (Harrison Butker kick), 0:34. Chiefs 35–7. Drive: 9 plays, 68 yards, 1:26.
  • SF – Robbie Gould 39-yard field goal, 0:00. Chiefs 35–10. Drive: 6 plays, 54 yards, 0:34.

Third quarter

  • SF – Marquise Goodwin 11-yard pass from Jimmy Garoppolo (kick failed), 8:59. Chiefs 35–16. Drive: 7 plays, 87 yards, 2:37.
  • SF – Alfred Morris 3-yard run (Jimmy Garoppolo-George Kittle pass), 2:43. Chiefs 35–24. Drive: 11 plays, 77 yards, 5:12.

Fourth quarter

  • KC – Harrison Butker 37-yard field goal, 13:47. Chiefs 38–24. Drive: 9 plays, 56 yards, 3:56.
  • SF – Robbie Gould 35-yard field goal, 5:17. Chiefs 38–27. Drive: 17 plays, 58 yards, 8:30.

|stats=

Top passers

  • SF – Jimmy Garoppolo – 20/30, 251 yards, 2 TD
  • KC – Patrick Mahomes – 24/38, 314 yards, 3 TD

Top rushers

  • SF – Matt Breida – 10 carries, 90 yards
  • KC – Kareem Hunt – 18 carries, 44 yards, 2 TD

Top receivers

  • SF – George Kittle – 5 receptions, 79 yards
  • KC – Travis Kelce – 8 receptions, 114 yards

}} Not only did the 49ers lose the game, Jimmy Garoppolo got carted off in the fourth quarter with a serious knee injury. The next day, an MRI further revealed that Garoppolo had torn his ACL, ruling him out for the rest of the season. The devastating loss dropped the 49ers to 1-2 on the season.

These two teams would meet again the following season in Super Bowl LIV, with the 49ers falling short 31–20.

==Week 4: at Los Angeles Chargers==

{{Americanfootballbox

|titlestyle={{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}};text-align:center;

|state=autocollapse

|title=Week Four: San Francisco 49ers at Los Angeles Chargers – Game summary

|date=September 30

|time=1:25 pm. PDT

|road=49ers

|R1=14|R2=3|R3=7|R4=3

|home=Chargers

|H1=6|H2=11|H3=9|H4=3

|stadium=StubHub Center, Carson, California

|attendance=25,397

|weather={{convert|78|F|C}}, sunny

|referee=Ronald Torbert

|TV=CBS

|TVAnnouncers=Andrew Catalon and James Lofton

|reference=[http://www.nfl.com/gamecenter/2018093010/2018/REG4/49ers@chargers Recap]

|scoring=

First quarter

Second quarter

  • SF – Robbie Gould 21-yard field goal, 4:59. 49ers 17–6. Drive: 21 plays, 72 yards, 10:44.
  • LAC – Austin Ekeler 22-yard pass from Philip Rivers (Philip Rivers-Melvin Gordon pass), 0:47. 49ers 17–14. Drive: 9 plays, 75 yards, 4:12.
  • LAC – Caleb Sturgis 48-yard field goal, 0:00. Tied 17–17. Drive: 3 plays, 2 yards, 0:13.

Third quarter

  • LAC – Melvin Gordon 6-yard pass from Philip Rivers (kick failed), 10:35. Chargers 23–17. Drive: 6 plays, 51 yards, 2:48.
  • LAC – Caleb Sturgis 25-yard field goal, 7:44. Chargers 26–17. Drive: 4 plays, 5 yards, 0:58.
  • SF – George Kittle 82-yard pass from C. J. Beathard (Robbie Gould kick), 2:50. Chargers 26–24. Drive: 2 plays, 84 yards, 0:47.

Fourth quarter

  • SF – Robbie Gould 33-yard field goal, 12:39. 49ers 27–26. Drive: 9 plays, 49 yards, 3:28.
  • LAC – Caleb Sturgis 21-yard field goal, 7:41. Chargers 29–27. Drive: 9 plays, 72 yards, 4:58.

|stats=

Top passers

  • SF – C. J. Beathard – 23/37, 298 yards, 2 TD, 2 INT
  • LAC – Philip Rivers – 25/39, 250 yards, 3 TD, 1 INT

Top rushers

  • SF – Matt Breida – 9 carries, 39 yards
  • LAC – Melvin Gordon – 15 carries, 104 yards

Top receivers

  • SF – George Kittle – 6 receptions, 125 yards, 1 TD
  • LAC – Keenan Allen – 7 receptions, 63 yards

}}

The first post-Garoppolo game of the season was a surprisingly competitive game, mostly due to safety Antone Exum getting a pick-six in the first quarter, but the 49ers still lost 29–27 and dropped to 1–3 on the season and 0–1 after Garoppolo's injury.

==Week 5: vs. Arizona Cardinals==

{{Americanfootballbox

|titlestyle={{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}};text-align:center;

|state=autocollapse

|title=Week Five: Arizona Cardinals at San Francisco 49ers – Game summary

|date=October 7

|time=1:25 pm. PDT

|road=Cardinals

|R1=7|R2=7|R3=0|R4=14

|home=49ers

|H1=6|H2=0|H3=0|H4=12

|stadium=Levi's Stadium, Santa Clara, California

|attendance=68,337

|weather={{convert|79|F|C}}, clear

|referee=Shawn Smith

|TV=Fox

|TVAnnouncers=Dick Stockton, Mark Schlereth and Jennifer Hale

|reference=[http://www.nfl.com/gamecenter/2018100710/2018/REG5/cardinals@49ers Recap]

|scoring=

First quarter

Second quarter

  • ARI – David Johnson 2-yard run (Phil Dawson kick), 11:00. Cardinals 14–6. Drive: 4 plays, 18 yards, 2:18.

Third quarter

  • No scoring plays

Fourth quarter

  • SF – Trent Taylor 1-yard pass from C. J. Beathard (two-point conversion failed), 6:51. Cardinals 14–12. 14 plays, 83 yards, 5:46.
  • ARI – Josh Bynes 23-yard fumble return (Phil Dawson kick), 4:33. Cardinals 21–12.
  • ARI – David Johnson 6-yard run (Phil Dawson kick), 3:21. Cardinals 28–12. Drive: 5 plays, 26 yards, 0:27.
  • SF – C. J. Beathard 1-yard run (two-point conversion failed), 1:29. Cardinals 28–18. Drive: 10 plays, 76 yards, 1:52.

|stats=

Top passers

Top rushers

Top receivers

}}

Playing a winless Cardinals team desperately seeking a win, the 49ers held rookie QB Josh Rosen in check, but were hurt by five offensive turnovers, one of which resulted in a defensive touchdown for Arizona. The 49ers drop to 1–4 (0–2 since Garoppolo's injury) heading into a Monday Night road game against the Packers.

==Week 6: at Green Bay Packers==

{{Americanfootballbox

|titlestyle={{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}};text-align:center;

|state=autocollapse

|title=Week Six: San Francisco 49ers at Green Bay Packers – Game summary

|date={{dow tooltip|October 15, 2018}}

|time=7:15 pm. CDT/5:15 pm. PDT

|road=49ers

|R1=14|R2=10|R3=3|R4=3

|home=Packers

|H1=17|H2=3|H3=3|H4=10

|stadium=Lambeau Field, Green Bay, Wisconsin

|attendance=77,642

|weather={{convert|37|F|C}}, clear

|referee=John Parry

|TV=ESPN/KGO

|TVAnnouncers=Joe Tessitore, Jason Witten, Booger McFarland and Lisa Salters

|reference=[http://www.nfl.com/gamecenter/2018101500/2018/REG6/49ers@packers Recap]

|scoring=

;First quarter

  • SF – Matt Breida 3-yard run (Robbie Gould kick), 11:04. 49ers 7–0. Drive: 7 plays, 75 yards, 4:01.
  • GB – Ty Montgomery 2-yard run (Mason Crosby kick), 9:20. Tied 7–7. Drive: 4 plays, 77 yards, 1:42.
  • GB – Mason Crosby 29-yard field goal, 7:42. Packers 10–7. Drive: 5 plays, 23 yards, 1:29.
  • GB – Davante Adams 9-yard pass from Aaron Rodgers (Mason Crosby kick), 2:02. Packers 17–7. Drive: 5 plays, 79 yards, 2:54.
  • SF – Marquise Goodwin 67-yard pass from C. J. Beathard (Robbie Gould kick), 0:36. Packers 17–14. Drive: 3 plays, 78 yards, 1:31.

;Second quarter

  • GB – Mason Crosby 39-yard field goal, 7:38. Packers 20–14. Drive: 9 plays, 23 yards, 4:38.
  • SF – Marquise Goodwin 30-yard pass from C. J. Beathard (Robbie Gould kick), 6:13. 49ers 21–20. Drive: 3 plays, 65 yards, 1:29.
  • SF – Robbie Gould 39-yard field goal, 0:04. 49ers 24–20. Drive: 11 plays, 32 yards, 5:07.

;Third quarter

  • GB – Mason Crosby 51-yard field goal, 11:21. 49ers 24–23. Drive: 7 plays, 42 yards, 3:43.
  • SF – Robbie Gould 44-yard field goal, 7:04. 49ers 27–23. Drive: 9 plays, 49 yards, 4:18.

;Fourth quarter

  • SF – Robbie Gould 43-yard field goal, 13:12. 49ers 30–23. Drive: 10 plays, 58 yards, 5:12.
  • GB – Davante Adams 16-yard pass from Aaron Rodgers (Mason Crosby kick), 2:00. Tied 30–30. Drive: 4 plays, 58 yards, 1:05.
  • GB – Mason Crosby 27-yard field goal, 0:03. Packers 33–30. Drive: 10 plays, 81 yards, 1:07.

|stats=

;Top passers

  • SF – C. J. Beathard – 16/23, 245 yards, 2 TD, INT
  • GB – Aaron Rodgers – 25/46, 425 yards, 2 TD

;Top rushers

;Top receivers

  • SF – Marquise Goodwin – 4 receptions, 126 yards, 2 TD
  • GB – Davante Adams – 10 receptions, 132 yards, 2 TD

}}

The 49ers held a 30–23 lead in the final three minutes, but Aaron Rodgers threw a touchdown pass to Davante Adams to tie the game with less than 2 minutes left. On the 49ers' next drive, a critical C. J. Beathard interception plus an illegal contact penalty on Richard Sherman in the final minute led to a 27-yard game-winning field goal by Mason Crosby to send the 49ers to a 33–30 loss and a 1–5 record heading into next week's home game against the undefeated Rams.

==Week 7: vs. Los Angeles Rams==

{{Americanfootballbox

|titlestyle={{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}};text-align:center;

|state=autocollapse

|title=Week Seven: Los Angeles Rams at San Francisco 49ers – Game summary

|date=October 21

|time=1:25 pm. PDT

|road=Rams

|R1=3|R2=19|R3=10|R4=7

|home=49ers

|H1=0|H2=7|H3=3|H4=0

|stadium=Levi's Stadium, Santa Clara, California

|attendance=66,597

|weather={{convert|62|F|C}}, clear

|referee=Walt Anderson

|TV=CBS

|TVAnnouncers=Kevin Harlan, Rich Gannon and Steve Tasker

|reference=[http://www.nfl.com/gamecenter/2018102111/2018/REG7/rams@49ers Recap]

|scoring=

First quarter

  • LAR – Greg Zuerlein 35-yard field goal, 6:34. Rams 3–0. Drive: 7 plays, 27 yards, 3:24.

Second quarter

  • LAR – Todd Gurley 7-yard run (Greg Zuerlein kick), 14:23. Rams 10–0. Drive: 4 plays, 21 yards, 1:37.
  • LAR – Punt blocked by Cory Littleton out of bounds in end zone for a safety, 12:59. Rams 12–0.
  • LAR – Greg Zuerlein 37-yard field goal, 10:05. Rams 15–0. Drive: 5 plays, 34 yards, 2:54.
  • LAR – Brandin Cooks 19-yard pass from Jared Goff (Greg Zuerlein kick), 2:30. Rams 22–0. Drive: 8 plays, 60 yards, 3:47.
  • SF – George Kittle 10-yard pass from C. J. Beathard (Robbie Gould kick), 0:13. Rams 22–7. Drive: 8 plays, 75 yards, 2:17.

Third quarter

  • LAR – Greg Zuerlein 33-yard field goal, 8:06. Rams 25–7. Drive: 11 plays, 60 yards, 4:46.
  • LAR – Todd Gurley 1-yard run (Greg Zuerlein kick), 6:04. Rams 32–7. Drive: 3 plays, 27 yards, 0:55.
  • SF – Robbie Gould 51-yard field goal, 2:37. Rams 32–10. Drive: 8 plays, 42 yards, 3:27.

Fourth quarter

  • LAR – Todd Gurley 12-yard pass from Jared Goff (Greg Zuerlein kick), 11:35. Rams 39–10. Drive: 2 plays, 13 yards, 0:38.

|stats=

Top passers

  • LAR – Jared Goff – 18/24, 202 yards, 2 TD
  • SF – C. J. Beathard – 15/27, 170 yards, 1 TD, 2 INT

Top rushers

Top receivers

  • LAR – Robert Woods – 5 receptions, 78 yards
  • SF – George Kittle – 5 receptions, 98 yards, 1 TD

}}

The loss to their NFC West and interstate rivals had the 49ers fall to 1-6 and 0-3 since Jimmy G's injury

==Week 8: at Arizona Cardinals==

{{Americanfootballbox

|titlestyle={{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}};text-align:center;

|state=autocollapse

|title=Week Eight: San Francisco 49ers at Arizona Cardinals – Game summary

|date=October 28

|time=1:25 p.m. MST & PDT

|road=49ers

|R1=2|R2=3|R3=7|R4=3

|home=Cardinals

|H1=0|H2=3|H3=0|H4=15

|stadium=State Farm Stadium, Glendale, Arizona

|attendance=61,923

|weather=Played indoors (retractable roof closed)

|referee=Brad Allen

|TV=Fox

|TVAnnouncers=Dick Stockton, Mark Schlereth and Jennifer Hale

|reference=[http://www.nfl.com/gamecenter/2018102809/2018/REG8/49ers@cardinals Recap]

|scoring=

First quarter

  • SF – Penalty on Josh Rosen enforced in ARI end zone for a safety, 4:17. 49ers 2–0.

Second quarter

  • ARI – Phil Dawson 31-yard field goal, 10:27. Cardinals 3–2. Drive: 12 plays, 78 yards, 6:33.
  • SF – Robbie Gould 27-yard field goal, 4:36. 49ers 5–3. Drive: 4 plays, 3 yards, 1:41.

Third quarter

Fourth quarter

  • SF – Robbie Gould 20-yard field goal, 13:37. 49ers 15–3. Drive: 11 plays, 73 yards, 6:14.
  • ARI – Larry Fitzgerald 13-yard pass from Josh Rosen (Phil Dawson kick), 11:11. 49ers 15–10. Drive: 6 plays, 75 yards, 2:27.
  • ARI – Christian Kirk 9-yard pass from Josh Rosen (Josh Rosen-Larry Fitzgerald pass), 0:39. Cardinals 18–15. Drive: 12 plays, 73 yards, 1:42.

|stats=

Top passers

Top rushers

Top receivers

}}

With the loss, the Niners dropped to 1–7 and last place in the NFC West. They were also swept by the Cardinals for the 4th consecutive year.

==Week 9: vs. Oakland Raiders==

{{Americanfootballbox

|titlestyle={{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}};text-align:center;

|state=autocollapse

|title=Week Nine: Oakland Raiders at San Francisco 49ers – Game summary

|date={{dow tooltip|November 1, 2018}}

|time=5:20 pm. PDT

|road=Raiders

|R1=3|R2=0|R3=0|R4=0

|home=49ers

|H1=7|H2=10|H3=14|H4=3

|stadium=Levi's Stadium, Santa Clara, California

|attendance=69,592

|weather={{convert|82|F|C}}, clear

|referee=Carl Cheffers

|TV=Fox/NFLN

|TVAnnouncers=Joe Buck, Troy Aikman, Erin Andrews and Kristina Pink

|reference=[http://www.nfl.com/gamecenter/2018110100/2018/REG9/raiders@49ers Recap]

|scoring=

First quarter

Second quarter

  • SF – Kendrick Bourne 4-yard pass from Nick Mullens (Robbie Gould kick), 12:40. 49ers 14–3. Drive: 13 plays, 66 yards, 7:24.
  • SF – Robbie Gould 39-yard field goal, 0:16. 49ers 17–3. Drive: 7 plays, 59 yards, 1:38.

Third quarter

  • SF – George Kittle 5-yard pass from Nick Mullens (Robbie Gould kick), 12:36. 49ers 24–3. Drive: 4 plays, 75 yards, 2:24.
  • SF – Raheem Mostert 52-yard run (Robbie Gould kick), 9:17. 49ers 31–3. Drive: 3 plays, 68 yards, 1:16.

Fourth quarter

  • SF – Robbie Gould 25-yard field goal, 3:59. 49ers 34–3. Drive: 8 plays, 22 yards, 5:32.

|stats=

Top passers

Top rushers

Top receivers

}}

This was the first start for Nick Mullens at QB, who replaced C. J. Beathard. The game was incredibly one-sided, with the 49ers winning by over 30 points. The Win was the final Battle of the Bay tying up the overall series at 5 but the victory put the 49ers at 2-7 for the season.

==Week 10: vs. New York Giants==

{{Americanfootballbox

|titlestyle={{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}};text-align:center;

|state=autocollapse

|title=Week Ten: New York Giants at San Francisco 49ers – Game summary

|date={{dow tooltip|November 12, 2018}}

|time=5:15 pm. PST

|road=Giants

|R1=7|R2=3|R3=10|R4=7

|home=49ers

|H1=3|H2=10|H3=7|H4=3

|stadium=Levi's Stadium, Santa Clara, California

|attendance=69,409

|weather={{convert|62|F|C}}, hazy

|referee= Shawn Hochuli

|TV=ESPN/KGO

|TVAnnouncers= Joe Tessitore, Jason Witten, Booger McFarland, and Lisa Salters

|reference=[http://www.nfl.com/gamecenter/2018111200/2018/REG10/giants@49ers Recap]

|scoring=

First quarter

Second quarter

  • SF – Matt Breida 3-yard run (Robbie Gould kick), 13:05. 49ers 10–7. Drive: 7 plays, 65 yards, 4:38.
  • NYG – Aldrick Rosas 20-yard field goal, 1:50. Tied 10–10. Drive: 14 plays, 55 yards, 6:45.
  • SF – Robbie Gould 36-yard field goal, 0:02. 49ers 13–10. Drive: 11 plays, 52 yards, 1:48.

Third quarter

  • SF – Matt Breida 11-yard pass from Nick Mullens (Robbie Gould kick), 8:09. 49ers 20–10. Drive: 11 plays, 65 yards, 6:51.
  • NYG – Odell Beckham Jr. 20-yard pass from Eli Manning (Aldrick Rosas kick), 6:36. 49ers 20–17. Drive: 4 plays, 53 yards, 1:33.
  • NYG – Aldrick Rosas 31-yard field goal, 2:10. Tied 20–20. Drive: 5 plays, 34 yards, 2:05.

Fourth quarter

  • SF – Robbie Gould 30-yard field goal, 2:46. 49ers 23–20. Drive: 11 plays, 54 yards, 6:11.
  • NYG – Sterling Shepard 3-yard pass from Eli Manning (Aldrick Rosas kick), 0:53. Giants 27–23. Drive: 9 plays, 69 yards, 1:53.

|stats=

Top passers

  • NYG – Eli Manning – 19/31, 188 yards, 3 TD
  • SF – Nick Mullens – 27/39, 250 yards, TD, 2 INT

Top rushers

  • NYG – Saquon Barkley – 20 carries, 67 yards
  • SF – Matt Breida – 17 carries, 101 yards, TD

Top receivers

  • NYG – Odell Beckham Jr. – 4 receptions, 73 yards, 2 TD
  • SF – George Kittle – 9 receptions, 83 yards

}}

With the loss, the 49ers fall to 2-8 this would secure their 5th consecutive season without a winning record.

==Week 12: at Tampa Bay Buccaneers==

{{Americanfootballbox

|titlestyle={{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}};text-align:center;

|state=autocollapse

|title=Week Twelve: San Francisco 49ers at Tampa Bay Buccaneers – Game summary

|date=November 25

|time=1:00 p.m. EST/10:00 am. PST

|road=49ers

|R1=0|R2=6|R3=3|R4=0

|home=Buccaneers

|H1=7|H2=6|H3=7|H4=7

|stadium=Raymond James Stadium, Tampa, Florida

|attendance=50,436

|weather={{convert|77|F|C}}, cloudy

|referee=John Parry

|TV=Fox

|TVAnnouncers=Kenny Albert, Ronde Barber and Jennifer Hale

|reference=[http://www.nfl.com/gamecenter/2018112507/2018/REG12/49ers@buccaneers Recap]

|scoring=

;First quarter

;Second quarter

  • SF – Dante Pettis 13-yard pass from Nick Mullens (kick failed), 8:32. Buccaneers 7–6. Drive: 9 plays, 79 yards, 5:42.
  • TB – Cairo Santos 41-yard field goal, 3:21. Buccaneers 10–6. Drive: 12 plays, 53 yards, 5:11.
  • TB – Cairo Santos 39-yard field goal, 0:06. Buccaneers 13–6. Drive: 8 plays, 38 yards, 1:37.

;Third quarter

  • SF – Robbie Gould 23-yard field goal, 11:02. Buccaneers 13–9. Drive: 10 plays, 78 yards, 3:58.

;Fourth quarter

  • TB – Peyton Barber 2-yard rush (Cairo Santos kick), 8:25. Buccaneers 20–9. Drive: 6 plays, 75 yards, 2:37.
  • TB – Adam Humphries 28-yard pass from Jameis Winston (Cairo Santos kick), 14:10. Buccaneers 27–9. Drive: 10 plays, 85 yards, 5:00.

|stats=

Top passers

  • SF – Nick Mullens – 18/32, 221 yards, 1 TD, 2 INT
  • TB – Jameis Winston – 29/38, 312 yards, 2 TD

Top rushers

  • SF – Matt Breida – 14 carries, 106 yards
  • TB – Peyton Barber – 18 carries, 47 yards, 1 TD

Top receivers

  • SF – Dante Pettis – 4 receptions, 77 yards, 1 TD
  • TB – Mike Evans – 6 receptions, 116 yards

}}

With the loss, the 49ers fall to 2-9, securing their 4th consecutive losing season.

==Week 13: at Seattle Seahawks==

{{Americanfootballbox

|titlestyle={{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}};text-align:center;

|state=autocollapse

|title=Week Thirteen: San Francisco 49ers at Seattle Seahawks – Game summary

|date=December 2

|time=1:25 pm. PST

|road=49ers

|R1=0|R2=3|R3=7|R4=6

|home=Seahawks

|H1=6|H2=14|H3=7|H4=16

|stadium=CenturyLink Field, Seattle, Washington

|attendance=69,009

|weather={{convert|45|F|C}}, cloudy

|referee=Clete Blakeman

|TV=Fox

|TVAnnouncers=Dick Stockton, Mark Schlereth and Jennifer Hale

|reference=[http://www.nfl.com/gamecenter/2018120213/2018/REG13/49ers@seahawks Recap]

|scoring=

First quarter

Second quarter

  • SEA – Tyler Lockett 52-yard pass from Russell Wilson (Sebastian Janikowski kick), 13:41. Seahawks 13–0. Drive: 2 plays, 57 yards, 1:12.
  • SEA – Doug Baldwin 1-yard pass from Russell Wilson (Sebastian Janikowski kick), 1:17. Seahawks 20–0. Drive: 5 plays, 33 yards, 0:34.
  • SF – Robbie Gould 45-yard field goal, 0:00. Seahawks 20–3. Drive: 7 plays, 30 yards, 1:17.

Third quarter

  • SEA – Rashaad Penny 20-yard rush (Sebastian Janikowski kick), 14:44. Seahawks 27–3. Drive: 1 plays, 20 yards, 0:16.
  • SF – Dante Pettis 17-yard pass from Nick Mullens (Robbie Gould kick), 11:24. Seahawks 27–10. Drive: 7 plays, 58 yards, 3:20.

Fourth quarter

  • SEA – Jaron Brown 18-yard pass from Russell Wilson (Sebastian Janikowski kick), 14:17. Seahawks 34–10. Drive: 6 plays, 88 yards, 3:23.
  • SF – Dante Pettis 75-yard pass from Nick Mullens (run failed), 14:06. Seahawks 34–16. Drive: 1 plays, 75 yards, 0:11.
  • SEA – Sebastian Janikowski 40-yard field goal, 7:46. Seahawks 37–16. Drive: 11 plays, 53 yards, 6:20.
  • SEA – Bobby Wagner 98-yard interception return (kick failed), 4:04. Seahawks 43–16.

|stats=

Top passers

  • SF – Nick Mullens – 30/48, 414 yards, 2 TD, 1 INT
  • SEA – Russell Wilson – 11/17, 185 yards, 4 TD

Top rushers

Top receivers

  • SF – Dante Pettis – 5 receptions, 129 yards, 2 TD
  • SEA – Jaron Brown – 3 receptions, 67 yards, 2 TD

}}

With the loss, The 49ers fall to 2-10 and 0-4 in the NFC West Division

==Week 14: vs. Denver Broncos==

{{Americanfootballbox

|titlestyle={{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}};text-align:center;

|state=autocollapse

|title=Week Fourteen: Denver Broncos at San Francisco 49ers – Game summary

|date=December 9

|time=1:05 pm. PST

|road=Broncos

|R1=0|R2=0|R3=7|R4=7

|home=49ers

|H1=3|H2=17|H3=0|H4=0

|stadium=Levi's Stadium, Santa Clara, California

|attendance=69,449

|weather={{convert|54|F|C}}, overcast

|referee=Shawn Smith

|TV=CBS

|TVAnnouncers=Andrew Catalon and James Lofton

|reference=[http://www.nfl.com/gamecenter/2018120910/2018/REG14/broncos@49ers Recap]

|scoring=

First quarter

  • SF – Robbie Gould 40-yard field goal, 10:23. 49ers 3–0. Drive: 9 plays, 56 yards, 4:37.

Second quarter

  • SF – Robbie Gould 29-yard field goal, 13:01. 49ers 6–0. Drive: 7 plays, 69 yards, 4:09.
  • SF – George Kittle 85-yard pass from Nick Mullens (Robbie Gould kick), 9:47. 49ers 13–0. Drive: 1 play, 85 yards, 0:13.
  • SF – Dante Pettis 1-yard pass from Nick Mullens (Robbie Gould kick), 0:08. 49ers 20–0. Drive: 7 plays, 72 yards, 0:59.

Third quarter

Fourth quarter

|stats=

Top passers

  • DEN – Case Keenum – 24/42, 186 yards, TD
  • SF – Nick Mullens – 20/33, 332 yards, 2 TD, INT

Top rushers

Top receivers

  • DEN – Tim Patrick – 7 receptions, 85 yards
  • SF – George Kittle – 7 receptions, 210 yards, TD

}}

With the victory, the 49ers snapped a 3 game losing streak and go up to 3-10 on the season.

==Week 15: vs. Seattle Seahawks==

{{Americanfootballbox

|titlestyle={{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}};text-align:center;

|state=autocollapse

|title=Week Fifteen: Seattle Seahawks at San Francisco 49ers – Game summary

|date=December 16

|time=1:05 pm. PST

|road=Seahawks

|R1=6|R2=7|R3=0|R4=10|R5=0

|home=49ers

|H1=7|H2=10|H3=3|H4=3|H5=3

|stadium=Levi's Stadium, Santa Clara, California

|attendance=68,836

|weather={{convert|61|F|C}}, cloudy

|referee=Pete Morelli

|TV=Fox

|TVAnnouncers=Thom Brennaman, Chris Spielman and Shannon Spake

|reference=[http://www.nfl.com/gamecenter/2018121609/2018/REG15/seahawks@49ers Recap]

|scoring=

First quarter

Second quarter

  • SF – Garrett Celek 41-yard pass from Nick Mullens (Robbie Gould kick), 9:29. 49ers 14–6. Drive: 10 plays, 98 yards, 5:22.
  • SEA – Doug Baldwin 35-yard pass from Russell Wilson (Sebastian Janikowski kick), 5:19. 49ers 14–13. Drive: 8 plays, 79 yards, 4:10.
  • SF – Robbie Gould 28-yard field goal, 1:05. 49ers 17–13. Drive: 9 plays, 66 yards, 4:14.

Third quarter

  • SF – Robbie Gould 33-yard field goal, 2:54. 49ers 20–13. Drive: 8 plays, 51 yards, 3:54.

Fourth quarter

  • SEA – Chris Carson 1-yard rush (Sebastian Janikowski kick), 13:51. Tied 20–20. Drive: 10 plays, 75 yards, 4:03.
  • SF – Robbie Gould 45-yard field goal, 9:51. 49ers 23–20. Drive: 7 plays, 48 yards, 4:00.
  • SEA – Sebastian Janikowski 48-yard field goal, 5:21. Tied 23–23. Drive: 7 plays, 45 yards, 4:30.

Overtime

  • SF – Robbie Gould 36-yard field goal, 3:06. 49ers 26–23. Drive: 7 plays, 44 yards, 4:19.

|stats=

Top passers

  • SEA – Russell Wilson – 23/31, 237 yards, 2 TD
  • SF – Nick Mullens – 20/29, 275 yards, TD

Top rushers

  • SEA – Chris Carson – 22 carries, 119 yards, TD
  • SF – Matt Breida – 17 carries, 50 yards

Top receivers

  • SEA – Doug Baldwin – 4 receptions, 77 yards, 2 TD
  • SF – Dante Pettis – 5 receptions, 83 yards

}}

This was the first time since 2013 that the 49ers beat the Seahawks, snapping a 10-game losing streak which dates back to the 2013 NFC Championship Game. This also prevented the Seahawks from clinching a Wild-Card Berth that week. The win would be the final win of the season putting the 49ers at 4-10.

==Week 16: vs. Chicago Bears==

{{Americanfootballbox

|titlestyle={{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}};text-align:center;

|state=autocollapse

|title=Week Sixteen: Chicago Bears at San Francisco 49ers – Game summary

|date=December 23

|time=1:05 pm. PST

|road=Bears

|R1=0|R2=7|R3=7|R4=0

|home=49ers

|H1=0|H2=9|H3=0|H4=0

|stadium=Levi's Stadium, Santa Clara, California

|attendance=70,806

|weather={{convert|50|F|C}}, partly cloudy

|referee=Alex Kemp

|TV=Fox

|TVAnnouncers=Thom Brennaman, Chris Spielman, and Shannon Spake

|reference=[http://www.nfl.com/gamecenter/2018122312/2018/REG16/bears@49ers Recap]

|scoring=

First quarter

  • No scoring plays.

Second quarter

  • SF- Robbie Gould 33-yard field goal, 10:54. 49ers 3-0. Drive: 12 plays, 48 yards, 6:26.
  • SF- Robbie Gould 30-yard field goal, 5:49. 49ers 6-0. Drive: 7 plays, 14 yards, 3:00.
  • CHI- Anthony Miller 4-yard pass from Mitchell Trubisky (Cody Parkey kick), 1:52. Bears 7-6. Drive: 8 plays, 75 yards, 3:57
  • SF- Robbie Gould 23-yard field goal, 0:00. 49ers 9-7. Drive: 8 plays, 63 yards, 1:52.

Third quarter

  • CHI- Jordan Howard 2-yard run (Cody Parkey kick), 4:14. Bears 14-9. Drive: 12 plays, 90 yards, 7:43.

Fourth quarter

  • No scoring plays.

|stats=

Top passers

Top rushers

Top receivers

}}

The 49ers fall in the Levi's season finale, dropping them to 4-11 on the season.

==Week 17: at Los Angeles Rams==

{{Americanfootballbox

|titlestyle={{NFLPrimaryStyle|San Francisco 49ers|year=2018|border=2}};text-align:center;

|state=autocollapse

|title=Week Seventeen: San Francisco 49ers at Los Angeles Rams – Game summary

|date=December 30

|time=1:25 pm. PST

|road=49ers

|R1=3|R2=7|R3=7|R4=15

|home=Rams

|H1=14|H2=17|H3=14|H4=3

|stadium=Los Angeles Memorial Coliseum, Los Angeles, California

|attendance=72,161

|weather={{convert|65|F|C}}, sunny

|referee=Jerome Boger

|TV=Fox

|TVAnnouncers=Thom Brennaman, Chris Spielman and Shannon Spake

|reference=[http://www.nfl.com/gamecenter/2018123014/2018/REG17/49ers@rams Recap]

|scoring=

First quarter

  • LAR – Brandin Cooks 3-yard pass from Jared Goff (Greg Zuerlein kick), 11:57. Rams 7–0. Drive: 3 plays, 7 yards, 1:08.
  • LAR – C. J. Anderson 1-yard run (Greg Zuerlein kick), 10:42. Rams 14–0. Drive: 2 plays, 13 yards, 0:19.
  • SF – Robbie Gould 30-yard field goal, 2:11. Rams 14–3. Drive: 5 plays, 58 yards, 2:29.

Second quarter

  • LAR – Cory Littleton 19-yard interception return (Greg Zuerlein kick), 12:37. Rams 21–3.
  • LAR – Brandin Cooks 18-yard pass from Jared Goff (Greg Zuerlein kick), 6:00. Rams 28–3. Drive: 11 plays, 86 yards, 5:10.
  • SF – Richie James 9-yard pass from Nick Mullens (Robbie Gould kick), 2:07. Rams 28–10. Drive: 8 plays, 75 yards, 3:53.
  • LAR – Greg Zuerlein 28-yard field goal, 0:00. Rams 31–10. Drive: 13 plays, 65 yards, 2:07.

Third quarter

  • LAR – Josh Reynolds 29-yard pass from Jared Goff (Greg Zuerlein kick), 12:19. Rams 38–10. Drive: 5 plays, 75 yards, 2:41.
  • SF – Alfred Morris 1-yard run (Greg Zuerlein kick), 8:23. Rams 38–17. Drive: 8 plays, 75 yards, 3:56.
  • LAR – Josh Reynolds 2-yard pass from Jared Goff (Greg Zuerlein kick), 11:57. Rams 45–17. Drive: 9 plays, 75 yards, 5:25.

Fourth quarter

  • LAR – Greg Zuerlein 51-yard field goal, 11:44. Rams 48–17. Drive: 7 plays, 19 yards, 3:41.
  • SF – Kendrick Bourne 2-yard pass from Nick Mullens (Robbie Gould kick), 6:54. Rams 48–24. Drive: 9 plays, 75 yards, 4:50.
  • SF – George Kittle 43-yard pass from Nick Mullens (Nick Mullens-Trent Taylor pass), 2:20. Rams 48–32. Drive: 2 plays, 49 yards, 0:17.

|stats=

Top passers

  • SF – Nick Mullens – 23/33, 282 yards, 3 TD, 3 INT
  • LAR – Jared Goff – 15/26, 199 yards, 4 TD

Top rushers

  • SF – Alfred Morris – 16 carries, 111 yards, TD
  • LAR – C. J. Anderson – 23 carries, 132 yards, TD

Top receivers

  • SF – George Kittle – 9 receptions, 149 yards, TD
  • LAR – Brandin Cooks – 5 receptions, 62 yards, 2 TD

}}

With the loss, the 49ers finished 0–8 on the road for the first time since 1979. The 49ers were swept by the Rams for the first time since 2004. During the season finale against the Rams, Kittle broke Travis Kelce's single-season receiving yards record for a tight end, less than an hour after Kelce broke the record, on a 43-yard touchdown and finished the season with 1,377 yards. The 49ers would end their season at 4-12.

=Standings=

==Division==

{{2018 NFC West standings|team=SF}}

==Conference==

{{2018 NFC standings|team=SF}}

References

{{reflist}}