202-CoV

{{short description|Vaccine candidate against COVID-19}}

{{Use dmy dates|date=August 2021}}

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| target = SARS-CoV-2

| vaccine_type = protein

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| routes_of_administration = Intramuscular

| CAS_number = 2699024-52-5

| CAS_number_Ref = {{cite web|url=https://www.wipo.int/edocs/pubdocs/en/wipo-pub-1075-en-covid-19-related-vaccines-and-therapeutics.pdf|title=Patent Landscape Report COVID-19-related vaccines and therapeutics}}

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202-CoV is a COVID-19 vaccine candidate developed by Shanghai Zerun Biotechnology Co., Ltd., Walvax Biotech.{{ClinicalTrialsGov|NCT04982068|Phase I Clinical Trial of Recombinant SARS-CoV-2 Spike Protein Vaccine (CHO Cell)}}{{ClinicalTrialsGov|NCT04990544|Phase II Clinical Trial of Recombinant SARS-CoV-2 Spike Protein Vaccine (CHO Cell)}}{{cite news |title=CEPI partners with Shanghai Zerun Biotech to develop COVID-19 variant vaccine |url=https://cepi.net/news_cepi/cepi-partners-with-shanghai-zerun-biotech-to-develop-covid-19-variant-vaccine/ |access-date=30 August 2021 |publisher=Coalition for Epidemic Preparedness Innovations |date=21 July 2021}} It is one of several candidates under development by Walvax.

Development

In May 2020, the Bill & Melinda Gates Foundation awarded Shanghai Zerun Biotechnology a $1,000,000 USD vaccine development grant to "support research and development for COVID-19 response".{{Cite web |date=May 2020 |title=Shanghai Zerun Biotechnology Co., Ltd. |url=https://www.gatesfoundation.org/about/committed-grants/2020/05/inv006445 |url-status=live |archive-url=https://web.archive.org/web/20221021073045/https://www.gatesfoundation.org/about/committed-grants/2020/05/inv006445 |archive-date=2022-10-21 |access-date=2022-10-21 |website=Bill & Melinda Gates Foundation |language=en}}

In July 2021, the Coalition for Epidemic Preparedness Innovations (CEPI) announced that it had partnered with Shanghai Zerun Biotechnology and its parent company, Walvax Biotech, to develop COVID-19 vaccine candidates against both the original strain of SARS-CoV-2 and its newer variants. As of October 2022, CEPI had provided up to $25.1 million USD towards 202-CoV, but had ceased further funding.{{Cite web |title=Our portfolio |url=https://cepi.net/research_dev/our-portfolio/ |url-status=live |archive-url=https://archive.today/20221021070715/https://cepi.net/research_dev/our-portfolio/ |archive-date=2022-10-21 |access-date=2022-10-21 |website=Coalition for Epidemic Preparedness Innovations (CEPI) |language=en-US}} The chimeric protein candidate remains in Phase I clinical trials.

References

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Category:Clinical trials related to COVID-19

Category:Chinese COVID-19 vaccines

Category:Science and technology in China

Category:Protein subunit vaccines

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