2021 Southeastern Louisiana Lions football team

The Southland Conference released their preseason poll in July 2021. The Lions were picked to finish first in the conference.{{cite web |title=Southeastern Voted to Top Spot in 2021 Football Preseason Poll |url=https://www.southland.org/news/2021/7/22/southeastern-voted-to-top-spot-in-2021-football-preseason-poll.aspx |website=www.southland.org |access-date=8 August 2021 |language=en}} In addition, sixteen Lions were chosen to the Preseason All-Southland Team.{{cite web |title=Southland Announces 2021 Preseason All-Conference Football Teams |url=https://www.southland.org/news/2021/7/15/southland-announces-2021-preseason-all-conference-football-teams.aspx |website=www.southland.org |access-date=8 August 2021 |language=en}}

class="wikitable" {{CollegePrimaryHeader|team=Southeastern Louisiana Lions|Predicted finish|Team|Votes (1st place)}}
align="center" | 1	Southeastern Louisiana	48 (8)
align="center" | 2	Nicholls	43 (4)
align="center" | 3	Incarnate Word	32
align="center" | 4	McNeese State	26
align="center" | 5	Northwestern State	21
align="center" | 6	Houston Baptist	10

{{col-begin}}

{{col-break}}

Offense

1st Team

• Cole Kelley – Quarterback, SR
• CJ Turner – Wide Receiver, RS-JR
• Jalen Bell – Offensive Lineman, JR
• Mateo Rengifo – Kicker, SO
• Austin Dunlap – Punter, SO

2nd Team

• Damien Dawson – Tight End/Halfback, RS-SR
• Austin Mitchell – Wide Receiver, RS-SR
• Ethan McMullan – Offensive Lineman, SR
• Rendon Miles-Character – Offensive Lineman, SR
• Drew Jones – Offensive Lineman, SR

{{col-break}}

Defense

1st Team

• Darrius Harry – Defensive Lineman, RS-FR
• Alexis Ramos – Linebacker, SR
• Ferlando Jordan – Defensive Back, RS-JR
• Donnell Ward-McGee – Defensive Back, JR

2nd Team

• Herman Christophe – Linebacker, SO
• Jack Henderson – Defensive Back, FR

{{col-end}}

{{American football roster/Header|year=2021|team=Southeastern Louisiana Lions|teamcolors=y

|offensive_players=

{{American football roster/Player|first=Damien|last=Dawson|num=0|pos=RB|class=SR|rs=y}}

{{American football roster/Player|first=Brennon|last=Dingle|num=1|pos=WR|class=SR}}

{{American football roster/Player|first=Anthony|last=Spurlock|num=3|pos=WR|class=SO|rs=y}}

{{American football roster/Player|first=Austin|last=Mitchell|num=4|pos=WR|class=SR|rs=y}}

{{American football roster/Player|first=Cephus|last=Johnson III|num=5|pos=QB|class=JR|link=y|dab=Cephus Johnson}}

{{American football roster/Player|first=Nick|last=Kovacs|num=6|pos=WR|class=JR}}

{{American football roster/Player|first=Terrell|last=Carter|num=7|pos=WR|class=JR}}

{{American football roster/Player|first=Tim|last=Wilson Jr|num=9|pos=WR|class=JR}}

{{American football roster/Player|first=Maurice|last=Massey|num=10|pos=WR|class=FR|rs=y}}

{{American football roster/Player|first=Bauer|last=Sharp|num=12|pos=QB|class=FR|link=y}}

{{American football roster/Player|first=Jordan|last=Loving|num=13|pos=TE|class=SO|rs=y}}

{{American football roster/Player|first=Jacob|last=Switzer|num=14|pos=QB|class=FR}}

{{American football roster/Player|first=Cole|last=Kelley|num=15|pos=QB|class=SR|link=y}}

{{American football roster/Player|first=Justin|last=Wendt|num=16|pos=WR|class=JR|rs=y}}

{{American football roster/Player|first=Christian|last=Westcott|num=18|pos=QB|class=FR}}

{{American football roster/Player|first=Eli|last=Sawyer|num=19|pos=QB|class=FR}}

{{American football roster/Player|first=Jordan|last=Griffin|num=20|pos=RB|class=SO|rs=y}}

{{American football roster/Player|first=Taron|last=Jones|num=22|pos=RB|class=JR}}

{{American football roster/Player|first=Jett|last=Booker|num=23|pos=WR|class=FR}}

{{American football roster/Player|first=Calvin|last=Jones|num=24|pos=WR|class=FR}}

{{American football roster/Player|first=Jessie|last=Britt|num=25|pos=RB|class=JR}}

{{American football roster/Player|first=Corey|last=Lorio|num=27|pos=WR|class=FR}}

{{American football roster/Player|first=Joseph|last=Wilson|num=29|pos=RB|class=FR}}

{{American football roster/Player|first=Jahmon|last=McClendon|num=33|pos=RB|class=FR|rs=y}}

{{American football roster/Player|first=Ivan|last=Drobocky|num=38|pos=TE|class=FR}}

{{American football roster/Player|first=Connor|last=Briggs|num=44|pos=TE|class=FR}}

{{American football roster/Player|first=Javin|last=Turner|num=52|pos=OL|class=FR}}

{{American football roster/Player|first=Holden|last=Kareokowsky|num=53|pos=OL|class=FR}}

{{American football roster/Player|first=Tyree'|last=Rhodes|num=54|pos=OL|class=JR|rs=y}}

{{American football roster/Player|first=John|last=Allen|num=55|pos=OL|class=SO}}

{{American football roster/Player|first=Brockhim|last=Wicks|num=56|pos=OL|class=FR|rs=y}}

{{American football roster/Player|first=Rendon|last=Miles-Character|num=61|pos=OL|class=SR}}

{{American football roster/Player|first=William|last=Granville|num=62|pos=OL|class=SO|rs=y}}

{{American football roster/Player|first=Dom|last=Serapiglia III|num=63|pos=OL|class=FR|rs=y}}

{{American football roster/Player|first=Noah|last=Devlin|num=64|pos=OL|class=FR}}

{{American football roster/Player|first=Cayden|last=Guzzardo|num=68|pos=OL|class=FR}}

{{American football roster/Player|first=Ethan|last=McMullan|num=70|pos=OL|class=SR}}

{{American football roster/Player|first=Gavin|last=Burtchaell|num=71|pos=OL|class=FR}}

{{American football roster/Player|first=Brennan|last=Lanclos|num=72|pos=OL|class=SO|rs=y}}

{{American football roster/Player|first=Jhy|last=Orgeron|num=73|pos=OL|class=FR}}

{{American football roster/Player|first=Jalen|last=Bell|num=74|pos=OL|class=JR}}

{{American football roster/Player|first=Blakely|last=Miller|num=75|pos=OL|class=FR}}

{{American football roster/Player|first=Drew|last=Jones|num=79|pos=OL|class=SR}}

{{American football roster/Player|first=Da'Shun|last=Hughley|num=80|pos=WR|class=FR}}

{{American football roster/Player|first=Malik|last=Hillard|num=81|pos=WR|class=FR}}

{{American football roster/Player|first=Gage|last=Larvadain|num=82|pos=WR|class=FR}}

{{American football roster/Player|first=CJ|last=Turner|num=83|pos=WR|class=JR|rs=y}}

{{American football roster/Player|first=Spencer|last=Owens|num=84|pos=TE|class=JR|rs=y}}

{{American football roster/Player|first=Tanner|last=Olsen|num=85|pos=TE|class=SO|rs=y}}

{{American football roster/Player|first=Ed|last=Magee|num=86|pos=WR|class=SO}}

{{American football roster/Player|first=Reginald|last=Patterson Jr.|num=87|pos=WR|class=FR}}

{{American football roster/Player|first=Nolan|last=Givan|num=88|pos=TE|class=SR}}

{{American football roster/Player|first=Cade|last=Collier|num=89|pos=TE|class=FR}}

|defensive_players=

{{American football roster/Player|first=Ferlando|last=Jordan|num=2|pos=DB|class=JR|rs=y}}

{{American football roster/Player|first=Coryell|last=Pierce|num=6|pos=DB|class=FR}}

{{American football roster/Player|first=Donniel|last=Ward-Magee|num=8|pos=DB|class=JR}}

{{American football roster/Player|first=Matt|last=Wright|num=11|pos=DB|class=SR|rs=y}}

{{American football roster/Player|first=Champ|last=Craven|num=12|pos=DB|class=FR|rs=y}}

{{American football roster/Player|first=Markell|last=Linzer|num=13|pos=DB|class=FR}}

{{American football roster/Player|first=Zy|last=Alexander|num=14|pos=DB|class=FR|link=y}}

{{American football roster/Player|first=Justin|last=Dumas|num=16|pos=DB|class=FR}}

{{American football roster/Player|first=Chinedu|last=Ogbonna|num=17|pos=LB|class=SR}}

{{American football roster/Player|first=Jack|last=Henderson|num=20|pos=DB|class=FR}}

{{American football roster/Player|first=Brandon|last=Barbee|num=21|pos=DB|class=JR}}

{{American football roster/Player|first=Blayne|last=Delahoussaye|num=23|pos=DB|class=FR}}

{{American football roster/Player|first=Alphonso|last=Taylor|num=24|pos=DB|class=SO}}

{{American football roster/Player|first=Taquan|last=Thomas|num=25|pos=DB|class=FR}}

{{American football roster/Player|first=Mark|last=Clement|num=26|pos=DB|class=FR}}

{{American football roster/Player|first=Justin|last=Douglas|num=27|pos=DB|class=SO}}

{{American football roster/Player|first=Tyrone|last=Legette|num=28|pos=DB|class=SO}}

{{American football roster/Player|first=Alexis|last=Ramos|num=30|pos=LB|class=SR}}

{{American football roster/Player|first=Robert|last=Buquoi|num=31|pos=DB|class=FR|rs=y}}

{{American football roster/Player|first=Mike|last=Mason|num=32|pos=LB|class=SR|rs=y}}

{{American football roster/Player|first=Max|last=Jubenville|num=33|pos=LB|class=FR}}

{{American football roster/Player|first=Arlen|last=Williams|num=34|pos=LB|class=SO|rs=y}}

{{American football roster/Player|first=Calvin|last=Watson Jr.|num=38|pos=DB|class=FR|rs=y}}

{{American football roster/Player|first=Gerald|last=Henderson|num=39|pos=LB|class=FR|rs=y}}

{{American football roster/Player|first=Gerald|last=Nathan|num=40|pos=LB|class=SO}}

{{American football roster/Player|first=Kevin|last=Bickham|num=41|pos=LB|class=FR}}

{{American football roster/Player|first=Taylor|last=Martin|num=41|pos=DB|class=FR}}

{{American football roster/Player|first=Edward|last=Wilson|num=42|pos=DB|class=FR}}

{{American football roster/Player|first=Donte'|last=Daniels|num=43|pos=LB|class=FR}}

{{American football roster/Player|first=Garrett|last=Crawford|num=45|pos=DL|class=SO}}

{{American football roster/Player|first=Herman|last=Christophe|num=46|pos=LB|class=SO}}

{{American football roster/Player|first=David|last=Ellis|num=47|pos=LB|class=FR}}

{{American football roster/Player|first=Dominic|last=Lamm|num=48|pos=LB|class=SO}}

{{American football roster/Player|first=Sci|last=Martin|num=49|pos=DL|class=SR}}

{{American football roster/Player|first=Tommy|last=Lee|num=50|pos=LB|class=FR}}

{{American football roster/Player|first=Josh|last=Cook|num=57|pos=LB|class=SO|rs=y}}

{{American football roster/Player|first=Rodney|last=Sopsher|num=58|pos=DL|class=SO}}

{{American football roster/Player|first=Kaleb|last=Hogg|num=65|pos=DL|class=SO|rs=y}}

{{American football roster/Player|first=Brendon|last=Kelley|num=78|pos=DL|class=SO|rs=y}}

{{American football roster/Player|first=Bryce|last=Cage|num=90|pos=DL|class=FR}}

{{American football roster/Player|first=Darrius|last=Harry|num=91|pos=LB|class=FR|rs=y}}

{{American football roster/Player|first=Nelson|last=Jenkins III|num=92|pos=DL|class=SO}}

{{American football roster/Player|first=Kam|last=Johnson|num=93|pos=DL|class=FR}}

{{American football roster/Player|first=Cherif|last=Seye|num=94|pos=DL|class=SO}}

{{American football roster/Player|first=Dalton|last=Allen|num=96|pos=DL|class=FR}}

{{American football roster/Player|first=Tyrik|last=Mitchell|num=97|pos=DL|class=FR|rs=y}}

{{American football roster/Player|first=Cullan|last=Scott|num=98|pos=DL|class=FR}}

{{American football roster/Player|first=John|last=Graves III|num=99|pos=DL|class=SO}}

|special_teams_players=

{{American football roster/Player|first=Austin|last=Dunlap|num=26|pos=P|class=SO}}

{{American football roster/Player|first=Nathan|last=Holliday|num=33|pos=K|pos2=P|class=SO|rs=y}}

{{American football roster/Player|first=Mateo|last=Rengifo|num=36|pos=K|class=SO}}

{{American football roster/Player|first=Aubrey|last=Bishop|num=42|pos=P|pos2=K|class=FR}}

{{American football roster/Player|first=Korey|last=Karbowsky|num=51|pos=LS|class=FR}}

{{American football roster/Player|first=Jake|last=Rotenberry|num=59|pos=LS|class=JR|rs=y}}

}}

{{American football roster/Footer|roster_url=https://lionsports.net/sports/football/roster/2021|accessdate=8 August 2021

|head_coach=

• Frank Scelfo (Northeast Louisiana)

|asst_coach=

• Greg Stevens (Eastern Oregon)
  Offensive coordinator/qb
  
• Raymond Monica (North Alabama)
  Defensive coordinator/lb
  
• Ross Jenkins ({{college|Louisiana Tech}})
  Special teams coordinator
  
• A. J. Hopp (Slippery Rock)
  Run game coordinator/ol
  
• Anthony Scelfo ({{college|Tulane}})
  Pass game coordinator/recruiting coordinator/te
  
• Giovanni Vizza ({{college|Texas A&M}})
  Wide receivers
  
• Albert Poree ({{college|Georgia Tech}})
  Running backs
  
• Bill D'Ottavio (Millersville)
  Safeties
  
• Del Lee-Collins (McNeese State)
  Cornerbacks
  
• Antonio Baker ({{college|Louisiana Tech}})
  Nickelbacks
  

}}

{{CFB schedule

| rankyear = 2021

| rankdivision = NCAA Division I FCS

| poll = STATS

| timezone = Central

|{{CFB schedule entry

| date = September 4

| time = 6:00 p.m.

| w/l = w

| away = y

| nonconf = y

| rank = 15

| opponent = North Alabama

| site_stadium = Braly Municipal Stadium

| site_cityst = Florence, AL{{efn|Southeastern Louisiana's game against North Alabama was originally scheduled to be played as a home game, in Hammond, but the game was moved to Florence, Alabama on August 31, 2021, due to safety concerns related to Hurricane Ida.{{cite web |last1=Kelley |first1=Kevin |title=North Alabama-SLU football game moved to Florence due to Hurricane Ida |url=https://fbschedules.com/north-alabama-slu-football-game-moved-to-florence-due-to-hurricane-ida/ |website=FBSchedules.com |access-date=August 31, 2021 |date=31 August 2021}}}}

| tv = ESPN3

| score = 49–28

| attend = 3,433

}}

|{{CFB schedule entry

| date = September 11

| time = 6:00 p.m.

| w/l = l

| nonconf = y

| away = y

| rank = 13

| opponent = Louisiana Tech

| opprank =

| site_stadium = Joe Aillet Stadium

| site_cityst = Ruston, LA

| tv = ESPN3

| score = 42–45

| attend = 15,328

}}

|{{CFB schedule entry

| date = September 18

| time = 11:00 a.m.

| w/l = w

| nonconf = y

| away = y

| rank = 15

| opponent = Central Connecticut

| opprank =

| site_stadium = Arute Field

| site_cityst = New Britain, CT

| score = 56–10

| attend = 3,117

}}

|{{CFB schedule entry

| date = October 2

| time = 12:00 p.m.

| w/l = w

| away = y

| rank = 14

| opponent = McNeese State

| site_stadium = Cowboy Stadium

| site_cityst = Lake Charles, LA

| tv = ESPN+

| score = 38–35

| attend = 6,044

}}

|{{CFB schedule entry

| date = October 9

| time = 12:00 p.m.

| w/l = w

| away = y

| rank = 14

| opponent = Nicholls

| opprank = 25

| site_stadium = John L. Guidry Stadium

| site_cityst = Thibodaux, LA

| gamename = River Bell Classic

| tv = ESPN+

| score = 58–48

| attend =7,402

}}

|{{CFB schedule entry

| date = October 16

| time = 4:00 p.m.

| w/l = w

| homecoming = y

| rank = 11

| opponent = Houston Baptist

| site_stadium = Strawberry Stadium

| site_cityst = Hammond, LA

| tv = ESPN+

| score = 61–24

| attend = 7,389

}}

|{{CFB schedule entry

| date = October 23

| time = 3:00 p.m.

| w/l = w

| away = y

| rank = 9

| opponent = Northwestern State

| opprank =

| site_stadium = Harry Turpin Stadium

| site_cityst = Natchitoches, LA

| gamename = rivalry

| tv = ESPN+

| score = 51–14

| attend = 6,523

}}

|{{CFB schedule entry

| date = October 30

| time = 6:00 p.m.

| w/l = w

| rank = 8

| opponent = McNeese State

| opprank =

| site_stadium = Strawberry Stadium

| site_cityst = Hammond, LA

| tv = ESPN+

| score = 23–20

| overtime =

| attend = 4,185

}}

|{{CFB schedule entry

| date = November 6

| time = 2:00 p.m.

| w/l = l

| away = y

| rank = 6

| opponent = No. 22 Incarnate Word

| site_stadium = Gayle and Tom Benson Stadium

| site_cityst = San Antonio, TX

| tv = ESPN+

| score = 52–55

| attend = 3,220

}}

|{{CFB schedule entry

| date = November 13{{efn|Southeastern Louisiana's home game against Northwestern State was originally scheduled to be played on September 25, but the game was moved on November 13, 2021, due to safety concerns related to Hurricane Ida.{{cite web|url=https://www.bogalusadailynews.com/2021/09/09/northwestern-slu-postponed/|title=Northwestern-SLU postponed|newspaper=Bogalusa Daily News|publisher=Boone Newspapers|date=September 9, 2021|access-date=March 16, 2025}}}}

| time = 6:00 p.m.

| w/l = w

| rank = 14

| opponent = Northwestern State

| site_stadium = Strawberry Stadium

| site_cityst = Hammond, LA

| gamename = rivalry

| tv = ESPN+

| score = 56–28

| attend =4,137

}}

|{{CFB schedule entry

| date = {{tooltip|November 18|Thursday}}

| time = 6:00 p.m.

| w/l = l

| rank = 15

| opponent = Nicholls

| site_stadium = Strawberry Stadium

| site_cityst = Hammond, LA

| gamename = River Bell Classic

| tv = ESPN+

| score = 42–45

| attend = 6,057

}}

|{{CFB schedule entry

| date = November 27

| time = 7:00 p.m.

| w/l = w

| rank = 18

| opprank = 22

| home = y

| nonconf = y

| opponent = Florida A&M

| gamename = FCS Playoffs First Round

| site_stadium = Strawberry Stadium

| site_cityst = Hammond, LA

| tv = ESPN+

| score = 38–14

| attend = 4,125

}}

|{{CFB schedule entry

| date = December 4

| time = 1:00 p.m.

| w/l = l

| rank = 18

| score = 20–59

| opprank = 2

| away = y

| nonconf = y

| opponent = James Madison

| gamename = FCS Playoffs Second Round

| site_stadium = Bridgeforth Stadium

| site_cityst = Harrisonburg, VA

| tv = ESPN+

| attend = 11,743

}}

}}

{{Cite web|title=2021 Southeastern Louisiana Lions Football Schedule|url=https://lionsports.net/sports/football/schedule/2021}}{{Cite web|title=2021 Southeastern Louisiana Lions Football Schedule|url=https://fbschedules.com/southeastern-louisiana-football-schedule/|website=FBSchedules.com}}{{Cite web|title=2021 SE Louisiana Lions Schedule|url=https://espn.com/college-football/team/schedule/_/id/2545/season/2021|website=ESPN.com}}

{{notelist}}

{{AFB game box start

|Title=Southeastern Louisiana at North Alabama

|Visitor=No. 15 SLU Lions

|Host=UNA Lions

|V1=7|V2=7|V3=13|V4=22

|H1=0|H2=14|H3=7|H4=7

|Date=September 4, 2021

|Location=Braly Municipal Stadium
Florence, AL

|TimeZone=CDT

|StartTime=6:00 p.m.

|ElapsedTime=3 hours and 36 minutes

|Attendance=3,433

|Weather={{Convert|NNNN|°F|°C}} • Weather: TBD • Wind: TBD

|Referee=Drew Myers

|TVAnnouncers=  

|TVStation=ESPN3

}}

{{AFB Game Box Scoring Entry|FirstEntry=yes|Quarter=1|Time=0:43|Team=SLU|Event=Nolan Givan 4-yard pass from Cole Kelley (Mateo Rengifo kick)
{{Small|(7 plays, 67 yards, 3:24)}}|Score=SLU 7–0}}

{{AFB Game Box Scoring Entry|Quarter=2|QuarterEntries=3|Time=13:03|Team=UNA|Event=Corson Swan 29-yard pass from Jaylen Gipson (Sam Contorno kick)
{{Small|(1 play, 29 yards, 0:13)}}|Score=TIED 7–7}}

{{AFB Game Box Scoring Entry|Time=6:12|Team=SLU|Event=Cephus Johnson III 13-yard pass from Cole Kelley (Mateo Rengifo kick)
{{Small|(17 plays, 68 yards, 6:51)}}|Score=SLU 14–7}}

{{AFB Game Box Scoring Entry|Time=1:39|Team=UNA|Event=Kennebrew Tak. 40-yard pass from Jaylen Gipson (Easterling Gra. kick)
{{Small|(8 plays, 75 yards, 4:33)}}|Score=TIED 14–14}}

{{AFB Game Box Scoring Entry|Quarter=3|QuarterEntries=3|Time=11:40|Team=SLU|Event=Austi Mitchell 1-yard pass from Cole Kelley (Mateo Rengifo kick failed)
{{Small|(7 plays, 61 yards, 3:20)}}|Score=SLU 20–14}}

{{AFB Game Box Scoring Entry|Time=9:37|Team=UNA|Event=Takairee Kennebrew 47-yard pass from Jaylen Gipson (Easterling Gra. kick)
{{Small|(4 plays, 75 yards, 2:03)}}|Score=UNA 21–20}}

{{AFB Game Box Scoring Entry|Time=6:37|Team=SLU|Event=Taron Jones 3-yard run (Mateo Rengifo kick)
{{Small|(7 plays, 75 yards, 3:00)}}|Score=SLU 27–21}}

{{AFB Game Box Scoring Entry|Quarter=4|QuarterEntries=4|Time=13:07|Team=SLU|Event=Cole Kelley 9-yard run (Nolan Givan pass)
{{Small|(13 plays, 99 yards, 6:29)}}|Score=SLU 35–21}}

{{AFB Game Box Scoring Entry|Time=12:38|Team=SLU|Event=Ferland Jordan 41-yard interception (Mateo Rengifo kick)|Score=SLU 42–21}}

{{AFB Game Box Scoring Entry|Time=10:21|Team=UNA|Event=Takairee Kennebrew 24-yard pass from Jaylen Gipson (Easterling Gra. kick)
{{Small|(8 plays, 75 yards, 2:17)}}|Score=SLU 42–28}}

{{AFB Game Box Scoring Entry|Time=0:44|Team=SLU|Event=Cephus Johnson III 15-yard run (Mateo Rengifo kick)
{{Small|(6 plays, 79 yards, 3:38)}}|Score=SLU 49–28|LastEntry=yes}}

{{AFB game box end}}

{{see also|2021 North Alabama Lions football team}}

class="wikitable"
align="center" ! style={{CollegeSecondaryStyle|Southeastern Louisiana Lions|color=white}}|Pregame line!!style={{CollegeSecondaryStyle|Southeastern Louisiana Lions|color=white}}|Over/under
align="center" |

class="wikitable" ! Statistics !! style="{{NCAA secondary color cell|Southeastern Louisiana Lions}}"|Southeastern Louisiana!!style="{{NCAA color cell|North Alabama Lions}}"|North Alabama
First downs	30	23
Total yards	495	404
Rushing yards	232	54
Passing yards	263	350
Turnovers	2	1
Time of possession	36:49	23:11

class="wikitable" style="float: left;" ! Team !! Category !! Player !! Statistics
rowspan=3 style="{{NCAA secondary color cell|Southeastern Louisiana Lions}}; text-align:center;"|Southeastern Louisiana	Passing	Cole Kelley	30/41, 263 yards, 3 TD
Rushing	Taron Jones	11 carries, 85 yards, 1 TD
Receiving	CJ Turner	3 receptions, 52 yards
rowspan=3 style="{{NCAA color cell|North Alabama Lions}}; text-align:center;"|North Alabama	Passing	Jaylen Gipson	23/46, 350 yards, 4 TD, 1 INT
Rushing	Jaylen Gipson	7 carries, 22 yards
Receiving	Takairee Kennebrew	7 receptions, 132 yards, 3 TD

{{Clear}}

{{AFB game box start

|Title=Southeastern Louisiana at Louisiana Tech

|Visitor=No. 13 Lions

|Host=Bulldogs

|V1=7|V2=14|V3=14|V4=7

|H1=14|H2=10|H3=14|H4=7

|Date=September 11, 2021

|Location=Joe Aillet Stadium
Ruston, LA

|TimeZone=CDT

|StartTime=6:00 p.m.

|ElapsedTime= 

|Attendance= 15,328

|Weather={{Convert|NNNN|°F|°C}} • Weather: Sunny • Wind: TBD

|Referee=Kevin Vicknair

|TVAnnouncers= Lyn Rollins and Chris Mycoskie

|TVStation=ESPN3

}}

{{AFB Game Box Scoring Entry|FirstEntry=yes|Quarter=1|QuarterEntries=3|Time=8:16|Team=LT|Event=BeeJay Williamson 45-yard interceptions return (Jacob Barnes kick)|Score=LT 7–0}}

{{AFB Game Box Scoring Entry|Time=4:06|Team=SELA|Event=Tim Wilson Jr. 4-yard pass from Cole Kelley (Mateo Rengifo kick)
{{Small|(12 plays, 91 yards, 4:02)}}|Score=TIED 7–7}}

{{AFB Game Box Scoring Entry|Time=0:33|Team=LT|Event=Greg Garner 4-yard run (Jacob Barnes kick)
{{Small|(12 plays, 86 yards, 3:27)}}|Score=LT 14–7}}

{{AFB Game Box Scoring Entry|Quarter=2|QuarterEntries=4|Time=12:11|Team=SELA|Event=Taron Jones 2-yard run (Mateo Rengifo)
{{Small|(6 plays, 75 yards, 3:22)}}|Score=TIED 14–14}}

{{AFB Game Box Scoring Entry|Time=8:04|Team=LT|Event=Austin Kendall 2-yard run (Jacob Barnes kick)
{{Small|(10 plays, 75 yards, 4:07)}}|Score=LT 21–14}}

{{AFB Game Box Scoring Entry|Time=4:33|Team=LT|Event=Jacob Barnes 44-yard field goal
{{Small|(6 plays, 9 yards, 2:19)}}|Score=LT 24–14}}

{{AFB Game Box Scoring Entry|Time=0:22|Team=SELA|Event=Cole Kelley 1-yard run (Mateo Rengifo kick)
{{Small|(14 plays, 91 yards, 4:07)}}|Score=LT 24–21}}

{{AFB Game Box Scoring Entry|Quarter=3|QuarterEntries=4|Time=12:19|Team=LT|Event=Greg Garner 33-yard pass from Kyle Maxwell (Jacob Barnes kick)
{{Small|(8 plays, 84 yards, 2:34)}}|Score=LT 31–21}}

{{AFB Game Box Scoring Entry|Time=11:12|Team=SELA|Event=C. J. Turner 47-yard pass from Cole Kelley (Mateo Rengifo kick)
{{Small|(3 plays, 75 yards, 1:07)}}|Score=LT 31–28}}

{{AFB Game Box Scoring Entry|Time=8:10|Team=LT|Event=Greg Garner 1-yard run (Jacob Barnes kick)
{{Small|(9 plays, 75 yards, 3:02)}}|Score=LT 38–28}}

{{AFB Game Box Scoring Entry|Time=1:33|Team=SELA|Event=Austin Mitchell 9-yard pass from Cole Kelley (Mateo Rengifo kick)
{{Small|(12 plays, 75 yards, 6:37)}}|Score=LT 38–35}}

{{AFB Game Box Scoring Entry|Quarter=4|QuarterEntries=2|Time=9:51|Team=LT|Event=Tre Harris 21-yard pass from Austin Kendall (Jacob Barnes kick)
{{Small|(9 plays, 93 yards, 4:17)}}|Score=LT 45–35}}

{{AFB Game Box Scoring Entry|Time=4:22|Team=SELA|Event=Cole Kelley 4-yard run (Mateo Rengifo kick)
{{Small|(14 plays, 75 yards, 5:29)}}|Score=LT 45–42|LastEntry=yes}}

{{AFB game box end}}

{{see also|2021 Louisiana Tech Bulldogs football team}}

class="wikitable"
align="center" ! style={{CollegeSecondaryStyle|Southeastern Louisiana Lions|color=black}}|Pregame line!!style={{CollegeSecondaryStyle|Southeastern Louisiana Lions|color=black}}|Over/under
align="center" |

class="wikitable" ! Statistics !! style="{{NCAA secondary color cell|Southeastern Louisiana Lions}}"|Southeastern Louisiana!!style="{{NCAA color cell|Louisiana Tech Bulldogs}}"|Louisiana Tech
First downs	32	23
Total yards	598	448
Rushing yards	103	198
Passing yards	495	250
Turnovers	3	1
Time of possession	32:48	27:12

class="wikitable" style="float: left;" ! Team !! Category !! Player !! Statistics
rowspan=3 style="{{NCAA secondary color cell|Southeastern Louisiana Lions}}; text-align:center;"|Southeastern Louisiana	Passing	Cole Kelley	44/59, 495 yards, 3 TD, 2 INT
Rushing	Cole Kelley	14 carries, 42 yards, 2 TD
Receiving	C. J. Turner	8 receptions, 131 yards, TD
rowspan=3 style="{{NCAA color cell|Louisiana Tech Bulldogs}}; text-align:center;"|Louisiana Tech	Passing	Austin Kendall	19/27, 217 yards, TD, INT
Rushing	Marcus Williams Jr.	18 carries, 99 yards
Receiving	Tre Harris	4 receptions, 72 yards, TD

{{Clear}}

{{AFB game box start

|Title=Southeastern Louisiana at Central Connecticut State

|Visitor=No. 15 Lions

|Host=Blue Devils

|V1=|V2=|V3=|V4=

|H1=|H2=|H3=|H4=

|Date=September 18, 2021

|Location=Arute Field
New Britain, CT

|TimeZone=CDT

|StartTime=11:00 a.m.

|ElapsedTime= 

|Attendance= 3,117

|Weather={{Convert|NNNN|°F|°C}} • Weather: TBD • Wind: TBD

|Referee= 

|TVAnnouncers=  

|TVStation= 

}}

{{AFB Game Box Scoring Entry|FirstEntry=yes|Quarter=1|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=2|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=3|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=4|Time=|Team=|Event=|Score=|LastEntry=yes}}

{{AFB game box end}}

{{see also|2021 Central Connecticut Blue Devils football team}}

class="wikitable"
align="center" ! style={{CollegeSecondaryStyle|Southeastern Louisiana Lions|color=black}}|Pregame line!!style={{CollegeSecondaryStyle|Southeastern Louisiana Lions|color=black}}|Over/under
align="center" |

class="wikitable" ! Statistics !! style="{{NCAA secondary color cell|Southeastern Louisiana Lions}}"|Southeastern Louisiana!!style="{{NCAA color cell|Central Connecticut Blue Devils}}"|Central Connecticut
First downs
Total yards
Rushing yards
Passing yards
Turnovers
Time of possession

class="wikitable" style="float: left;" ! Team !! Category !! Player !! Statistics
rowspan=3 style="{{NCAA secondary color cell|Southeastern Louisiana Lions}}; text-align:center;"|Southeastern Louisiana	Passing
Rushing
Receiving
rowspan=3 style="{{NCAA color cell|Central Connecticut Blue Devils}}; text-align:center;"|Central Connecticut	Passing
Rushing
Receiving

{{Clear}}

{{AFB game box start

|Title=Southeastern Louisiana at McNeese State

|Visitor=No. 14 Lions

|Host=Cowboys

|V1=14|V2=10|V3=7|V4=7

|H1=7|H2=0|H3=14|H4=14

|Date=October 2, 2021

|Location=Cowboys Stadium
Lake Charles, LA

|TimeZone=CDT

|StartTime=12:00 p.m.

|ElapsedTime= 3:36

|Attendance= 6,044

|Weather={{Convert|79|°F|°C}} • Weather: Cloudy • Wind: SE 9

|Referee= Ed Bourgeois

|TVAnnouncers=  

|TVStation=CST/ESPN+

}}

{{AFB Game Box Scoring Entry|FirstEntry=yes|Quarter=1|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=2|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=3|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=4|Time=|Team=|Event=|Score=|LastEntry=yes}}

{{AFB game box end}}

{{see also|2021 McNeese State Cowboys football team}}

class="wikitable"
align="center" ! style={{CollegeSecondaryStyle|Southeastern Louisiana Lions|color=black}}|Pregame line!!style={{CollegeSecondaryStyle|Southeastern Louisiana Lions|color=black}}|Over/under
align="center" |

class="wikitable" ! Statistics !! style="{{NCAA secondary color cell|Southeastern Louisiana Lions}}"|Southeastern Louisiana!!style="{{NCAA color cell|McNeese State Cowboys}}"|McNeese State
First downs
Total yards
Rushing yards
Passing yards
Turnovers
Time of possession

class="wikitable" style="float: left;" ! Team !! Category !! Player !! Statistics
rowspan=3 style="{{NCAA secondary color cell|Southeastern Louisiana Lions}}; text-align:center;"|Southeastern Louisiana	Passing
Rushing
Receiving
rowspan=3 style="{{NCAA color cell|McNeese State Cowboys}}; text-align:center;"|McNeese State	Passing
Rushing
Receiving

{{Clear}}

{{AFB game box start

|Title=Southeastern Louisiana at Nicholls

|Visitor=No. 14 Lions

|Host=No. 25 Colonels

|V1=7|V2=24|V3=14|V4=13

|H1=7|H2=7|H3=21|H4=13

|Date=October 9, 2021

|Location=Manning Field at John L. Guidry Stadium
Thibodaux, LA

|TimeZone=CDT

|StartTime=12:00 p.m.

|ElapsedTime= 3:17

|Attendance= 7,402

|Weather={{Convert|83|°F|°C}} • Weather: Clear and sunny • Wind: 2mph NNE

|Referee= Gary Leeper

|TVAnnouncers=  

|TVStation=ESPN+

}}

{{AFB Game Box Scoring Entry|FirstEntry=yes|Quarter=1|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=2|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=3|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=4|Time=|Team=|Event=|Score=|LastEntry=yes}}

{{AFB game box end}}

{{see also|2021 Nicholls Colonels football team|River Bell Classic}}

class="wikitable"
align="center" ! style={{CollegeSecondaryStyle|Southeastern Louisiana Lions|color=black}}|Pregame line!!style={{CollegeSecondaryStyle|Southeastern Louisiana Lions|color=black}}|Over/under
align="center" |  NSU-1	72.5

class="wikitable" ! Statistics !! style="{{NCAA secondary color cell|Southeastern Louisiana Lions}}"|Southeastern Louisiana!!style="{{NCAA color cell|Nicholls Colonels}}"|Nicholls
First downs	32	26
Total yards	573	507
Rushing yards	167	209
Passing yards	406	298
Turnovers	1	0
Time of possession	37:51	22:09

class="wikitable" style="float: left;" ! Team !! Category !! Player !! Statistics
rowspan=3 style="{{NCAA secondary color cell|Southeastern Louisiana Lions}}; text-align:center;"|Southeastern Louisiana	Passing
Rushing
Receiving
rowspan=3 style="{{NCAA color cell|Nicholls Colonels}}; text-align:center;"|Nicholls	Passing
Rushing
Receiving

{{Clear}}

{{AFB game box start

|Title=Houston Baptist at Southeastern Louisiana

|Visitor=Huskies

|Host=No. 11 Lions

|V1=|V2=|V3=|V4=

|H1=|H2=|H3=|H4=

|Date=October 16, 2021

|Location=Strawberry Stadium
Hammond, LA

|TimeZone=CDT

|StartTime=4:00 p.m.

|ElapsedTime= 

|Attendance= 7,389

|Weather={{Convert|NNNN|°F|°C}} • Weather: TBD • Wind: TBD

|Referee= 

|TVAnnouncers=  

|TVStation=ESPN+

}}

{{AFB Game Box Scoring Entry|FirstEntry=yes|Quarter=1|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=2|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=3|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=4|Time=|Team=|Event=|Score=|LastEntry=yes}}

{{AFB game box end}}

{{see also|2021 Houston Baptist Huskies football team}}

class="wikitable"
align="center" ! style={{CollegePrimaryStyle|Southeastern Louisiana Lions|color=white}}|Pregame line!!style={{CollegePrimaryStyle|Southeastern Louisiana Lions|color=white}}|Over/under
align="center" |

class="wikitable" ! Statistics !! style="{{NCAA secondary color cell|Houston Baptist Huskies}}"|Houston Baptist!!style="{{NCAA color cell|Southeastern Louisiana Lions}}"|Southeastern Louisiana
First downs
Total yards
Rushing yards
Passing yards
Turnovers
Time of possession

class="wikitable" style="float: left;" ! Team !! Category !! Player !! Statistics
rowspan=3 style="{{NCAA secondary color cell|Houston Baptist Huskies}}; text-align:center;"|Houston Baptist	Passing
Rushing
Receiving
rowspan=3 style="{{NCAA color cell|Southeastern Louisiana Lions}}; text-align:center;"|Southeastern Louisiana	Passing
Rushing
Receiving

{{Clear}}

{{AFB game box start

|Title=Southeastern Louisiana at Northwestern State

|Visitor=No. 9 Lions

|Host=Demons

|V1=|V2=|V3=|V4=

|H1=|H2=|H3=|H4=

|Date=October 23, 2021

|Location=Harry Turpin Stadium
Natchitoches, LA

|TimeZone=CDT

|StartTime=3:00 p.m.

|ElapsedTime= 

|Attendance= 6,523

|Weather={{Convert|NNNN|°F|°C}} • Weather: TBD • Wind: TBD

|Referee= 

|TVAnnouncers=  

|TVStation=ESPN+

}}

{{AFB Game Box Scoring Entry|FirstEntry=yes|Quarter=1|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=2|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=3|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=4|Time=|Team=|Event=|Score=|LastEntry=yes}}

{{AFB game box end}}

{{see also|2021 Northwestern State Demons football team|Northwestern State–Southeastern Louisiana football rivalry}}

class="wikitable"
align="center" ! style={{CollegeSecondaryStyle|Southeastern Louisiana Lions|color=black}}|Pregame line!!style={{CollegeSecondaryStyle|Southeastern Louisiana Lions|color=black}}|Over/under
align="center" |

class="wikitable" ! Statistics !! style="{{NCAA secondary color cell|Southeastern Louisiana Lions}}"|Southeastern Louisiana!!style="{{NCAA color cell|Northwestern State Demons}}"|Northwestern State
First downs
Total yards
Rushing yards
Passing yards
Turnovers
Time of possession

class="wikitable" style="float: left;" ! Team !! Category !! Player !! Statistics
rowspan=3 style="{{NCAA secondary color cell|Southeastern Louisiana Lions}}; text-align:center;"|Southeastern Louisiana	Passing
Rushing
Receiving
rowspan=3 style="{{NCAA color cell|Northwestern State Demons}}; text-align:center;"|Northwestern State	Passing
Rushing
Receiving

{{Clear}}

{{AFB game box start

|Title=McNeese State at Southeastern Louisiana

|Visitor=Cowboys

|Host=No. 8 Lions

|V1=7|V2=0|V3=0|V4=13

|H1=3|H2=0|H3=7|H4=13

|Date=October 30, 2021

|Location=Strawberry Stadium
Hammond, LA

|TimeZone=CDT

|StartTime=6:00 p.m.

|ElapsedTime= 3:20

|Attendance= 4,185

|Weather={{Convert|65|°F|°C}} • Weather: Clear • Wind: NW 7

|Referee= Craig Heiser

|TVAnnouncers=  

|TVStation=ESPN+

}}

{{AFB Game Box Scoring Entry|FirstEntry=yes|Quarter=1|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=2|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=3|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=4|Time=|Team=|Event=|Score=|LastEntry=yes}}

{{AFB game box end}}

{{see also|2021 McNeese State Cowboys football team}}

class="wikitable"
align="center" ! style={{CollegePrimaryStyle|Southeastern Louisiana Lions|color=white}}|Pregame line!!style={{CollegePrimaryStyle|Southeastern Louisiana Lions|color=white}}|Over/under
align="center" |

class="wikitable" ! Statistics !! style="{{NCAA secondary color cell|McNeese State Cowboys}}"|McNeese State!!style="{{NCAA color cell|Southeastern Louisiana Lions}}"|Southeastern Louisiana
First downs
Total yards
Rushing yards
Passing yards
Turnovers
Time of possession

class="wikitable" style="float: left;" ! Team !! Category !! Player !! Statistics
rowspan=3 style="{{NCAA secondary color cell|McNeese State Cowboys}}; text-align:center;"|McNeese State	Passing
Rushing
Receiving
rowspan=3 style="{{NCAA color cell|Southeastern Louisiana Lions}}; text-align:center;"|Southeastern Louisiana	Passing
Rushing
Receiving

{{Clear}}

{{AFB game box start

|Title=Southeastern Louisiana at Incarnate Word

|Visitor=No. 6 Lions

|Host=No. 22 Cardinals

|V1=7|V2=10|V3=21|V4=14

|H1=7|H2=21|H3=14|H4=13

|Date=November 6, 2021

|Location=Gayle and Tom Benson Stadium
San Antonio, TX

|TimeZone=CDT

|StartTime=2:00 p.m.

|ElapsedTime=3 hours and 53 minutes

|Attendance=3,220

|Weather={{Convert|68|°F|°C}} • Weather: Clear, Sunny • Wind: SE 2 mph

|Referee=Ed Bourgeois

|TVAnnouncers=David Saltzman (play-by-play), Taylor McHargue (analyst), Lainie Fritz (sideline)

|TVStation=ESPN+

}}

{{AFB Game Box Scoring Entry|FirstEntry=yes|Quarter=1|QuarterEntries=2|Time=5:10|Team=UIW|Event=Taylor Grimes 16-yard pass from Cameron Ward (Carson Mohr kick)
{{Small|(3 plays, 79 yards, 0:58)}}|Score=UIW 7–7}}

{{AFB Game Box Scoring Entry|Time=0:07|Team=SLU|Event=Cole Kelley 4-yard run (Mateo Rengifo kick)
{{Small|(11 plays, 77 yards, 4:56)}}|Score=TIED 7–7}}

{{AFB Game Box Scoring Entry|Quarter=2|QuarterEntries=5|Time=14:18|Team=UIW|Event=Darion Chafin 31-yard pass from Cameron Ward (Carson Mohr kick)
{{Small|(7 plays, 75 yards, 0:49)}}|Score=UIW 14–7}}

{{AFB Game Box Scoring Entry|Time=10:52|Team=SLU|Event=Mateo Rengifo 36-yard field goal
{{Small|(10 plays, 60 yards, 3:20)}}|Score=UIW 14–10}}

{{AFB Game Box Scoring Entry|Time=4:58|Team=UIW|Event=Robert Ferrel 2-yard pass from Cameron Ward (Carson Mohr kick)
{{Small|(9 plays, 79 yards, 2:58)}}|Score=UIW 21–10}}

{{AFB Game Box Scoring Entry|Time=1:31|Team=SLU|Event=Nolan Givan 7-yard pass from Cole Kelley (Mateo Rengifo kick)
{{Small|(10 plays, 65 yards, 3:27)}}|Score=UIW 21–17}}

{{AFB Game Box Scoring Entry|Time=0:20|Team=UIW|Event=Darion Chafin 6-yard pass form Cameron Ward (Carson Mohr kick)
{{Small|(8 plays, 75 yards, 2:46)}}|Score=UIW 28–17}}

{{AFB Game Box Scoring Entry|Quarter=3|QuarterEntries=5|Time=12:14|Team=SLU|Event=Cole Kelley 3-yard run (Mateo Rengifo kick)
{{Small|(6 plays, 75 yards, 2:46)}}|Score=UIW 28–24}}

{{AFB Game Box Scoring Entry|Time=10:27|Team=UIW|Event=Taylor Grimes 25-yard pass from Cameron Ward (Carson Mohr kick)
{{Small|(6 plays, 82 yards, 1:40)}}|Score=UIW 35–24}}

{{AFB Game Box Scoring Entry|Time=7:30|Team=SLU|Event=Austin Mitchell 49-yard pass from Cole Kelley (Mateo Rengifo kick)
{{Small|(7 plays, 75 yards, 2:57)}}|Score=UIW 35–31}}

{{AFB Game Box Scoring Entry|Time=6:40|Team=UIW|Event=CJ Hardy 37-yard pass from Cameron Ward (Carson Mohr kick)
{{Small|(5 plays, 73 yards, 0:50)}}|Score=UIW 42–31}}

{{AFB Game Box Scoring Entry|Time=2:36|Team=SLU|Event=Gage Larvadain 10-yard pass from Cole Kelley (Mateo Rengifo kick)
{{Small|(11 plays, 75 yards, 4:04)}}|Score=UIW 42–38}}

{{AFB Game Box Scoring Entry|Quarter=4|QuarterEntries=4|Time=11:22|Team=SLU|Event=Taron Jones 2-yard run (Mateo Rengifo kick)
{{Small|(11 plays, 87 yards, 4:12)}}|Score=SLU 45–42}}

{{AFB Game Box Scoring Entry|Time=4:05|Team=UIW|Event=Kevin Brown 80-yard pass from Cameron Ward (Carson Mohr kick)
{{Small|(4 plays, 91 yards, 1:14)}}|Score=UIW 49–45}}

{{AFB Game Box Scoring Entry|Time=1:55|Team=SLU|Event=Cole Kelley 4-yard run (Mateo Rengifo kick)
{{Small|(5 plays, 75 yards, 2:10)}}|Score=SLU 52–49}}

{{AFB Game Box Scoring Entry|Time=0:25|Team=UIW|Event=Robert Ferrel 24-yard pass from Cameron Ward (Carson Mohr kick failed)
{{Small|(9 plays, 75 yards, 1:30)}}|Score=UIW 55–52|LastEntry=yes}}

{{AFB game box end}}

{{see also|2021 Incarnate Word Cardinals football team}}

class="wikitable"
align="center" ! style={{CollegeSecondaryStyle|Southeastern Louisiana Lions|color=black}}|Pregame line!!style={{CollegeSecondaryStyle|Southeastern Louisiana Lions|color=black}}|Over/under
align="center" |

class="wikitable" ! Statistics !! style="{{NCAA secondary color cell|Southeastern Louisiana Lions}}"|Southeastern Louisiana!!style="{{NCAA color cell|Incarnate Word Cardinals}}"|Incarnate Word
First downs	44	29
Total yards	774	711
Rushing yards	127	95
Passing yards	647	616
Turnovers	0	2
Time of possession	42:22	17:38

class="wikitable" style="float: left;" ! Team !! Category !! Player !! Statistics
rowspan=3 style="{{NCAA secondary color cell|Southeastern Louisiana Lions}}; text-align:center;"|Southeastern Louisiana	Passing	Cole Kelley	50/68, 647 yards, 3 TD
Rushing	Taron Jones	10 carries, 56 yards, 1 TD
Receiving	Austin Mitchell	9 receptions, 169 yards, 1 TD
rowspan=3 style="{{NCAA color cell|Incarnate Word Cardinals}}; text-align:center;"|Incarnate Word	Passing	Cam Ward	34/52, 610 yards, 7 TD, 1 INT
Rushing	Kevin Brown	6 carries, 65 yards
Receiving	Taylor Grimes	12 receptions, 193 yards, 2 TD

{{Clear}}

{{AFB game box start

|Title=Northwestern State at Southeastern Louisiana

|Visitor=Demons

|Host=No. 16 Lions

|V1=|V2=|V3=|V4=

|H1=|H2=|H3=|H4=

|Date=November 13, 2021

|Location=Strawberry Stadium
Hammond, LA

|TimeZone=CDT

|StartTime=6:00 p.m.

|ElapsedTime= 

|Attendance= 4,137

|Weather={{Convert|NNNN|°F|°C}} • Weather: TBD • Wind: TBD

|Referee= 

|TVAnnouncers=  

|TVStation=ESPN+

}}

{{AFB Game Box Scoring Entry|FirstEntry=yes|Quarter=1|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=2|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=3|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=4|Time=|Team=|Event=|Score=|LastEntry=yes}}

{{AFB game box end}}

{{see also|2021 Northwestern State Demons football team|Northwestern State–Southeastern Louisiana football rivalry}}

class="wikitable"
align="center" ! style={{CollegePrimaryStyle|Southeastern Louisiana Lions|color=white}}|Pregame line!!style={{CollegePrimaryStyle|Southeastern Louisiana Lions|color=white}}|Over/under
align="center" |

class="wikitable" ! Statistics !! style="{{NCAA secondary color cell|Northwestern State Demons}}"|Northwestern State!!style="{{NCAA color cell|Southeastern Louisiana Lions}}"|Southeastern Louisiana
First downs
Total yards
Rushing yards
Passing yards
Turnovers
Time of possession

class="wikitable" style="float: left;" ! Team !! Category !! Player !! Statistics
rowspan=3 style="{{NCAA secondary color cell|Northwestern State Demons}}; text-align:center;"|Northwestern State	Passing
Rushing
Receiving
rowspan=3 style="{{NCAA color cell|Southeastern Louisiana Lions}}; text-align:center;"|Southeastern Louisiana	Passing
Rushing
Receiving

{{Clear}}

{{AFB game box start

|Title=Nicholls at Southeastern Louisiana

|Visitor=Colonels

|Host=No. 15 Lions

|V1=21|V2=0|V3=17|V4=7

|H1=14|H2=14|H3=0|H4=14

|Date={{tooltip|November 18, 2021|Thursday}}

|Location=Strawberry Stadium
Hammond, LA

|TimeZone=CST

|StartTime=6:00 p.m.

|ElapsedTime= 3:45

|Attendance= 6,057

|Weather={{Convert|59|°F|°C}} • Weather: Cloudy • Wind: N13mph

|Referee= Gary Leeper

|TVAnnouncers=  

|TVStation=ESPN+

}}

{{AFB Game Box Scoring Entry|FirstEntry=yes|Quarter=1|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=2|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=3|Time=|Team=|Event=|Score=}}

{{AFB Game Box Scoring Entry|Quarter=4|Time=|Team=|Event=|Score=|LastEntry=yes}}

{{AFB game box end}}

{{see also|2021 Nicholls Colonels football team|River Bell Classic}}

class="wikitable"
align="center" ! style={{CollegePrimaryStyle|Southeastern Louisiana Lions|color=white}}|Pregame line!!style={{CollegePrimaryStyle|Southeastern Louisiana Lions|color=white}}|Over/under
align="center" |  SEL –7.5	78

class="wikitable" ! Statistics !! style="{{NCAA secondary color cell|Nicholls Colonels}}"|Nicholls!!style="{{NCAA color cell|Southeastern Louisiana Lions}}"|Southeastern Louisiana
First downs	28	26
Total yards	556	496
Rushing yards	292	111
Passing yards	264	385
Turnovers	2	1
Time of possession	33:29	26:31

class="wikitable" style="float: left;" ! Team !! Category !! Player !! Statistics
rowspan=3 style="{{NCAA secondary color cell|Nicholls Colonels}}; text-align:center;"|Nicholls	Passing
Rushing
Receiving
rowspan=3 style="{{NCAA color cell|Southeastern Louisiana Lions}}; text-align:center;"|Southeastern Louisiana	Passing
Rushing
Receiving

{{Clear}}

{{Linescore Amfootball|

|Road=No. 22 Florida A&M

|R1=0

|R2=0

|R3=0

|R4=14

|Home=No. 18 Lions

|H1=7

|H2=17

|H3=7

|H4=7

}}

{{See also|2021 Florida A&M Rattlers football team|2021 NCAA Division I FCS football season}}

{{Clear}}

{{Linescore Amfootball|

|Road=No. 18 Lions

|R1=10

|R2=3

|R3=0

|R4=7

|Home=No. 3 Dukes

|H1=14

|H2=24

|H3=21

|H4=0

}}

{{See also|2021 James Madison Dukes football team|2021 NCAA Division I FCS football season}}

{{Clear}}

{{Reflist}}

{{Southeastern Louisiana Lions football navbox}}

Southeastern Louisiana

Category:Southeastern Louisiana Lions football seasons

Category:2021 NCAA Division I FCS playoff participants

Southeastern Louisiana Lions football