2022 Ghana Marburg virus disease outbreak
{{Short description|Disease outbreak in Ghana}}
{{Use dmy dates|date=June 2023}}
{{Infobox outbreak
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| caption = Micrograph of Marburg viruses
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| disease = Marburg virus
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| location = Ashanti Region, Ghana
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| date = July 2022
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| confirmed_cases = 4
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| deaths = 3
| fatality_rate = 75.00%
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In July 2022, an outbreak of Marburg virus disease occurred in Ghana.{{cite news|date=8 July 2022|title=Two test positive in Ghana for highly infectious Marburg virus|url=https://www.reuters.com/business/healthcare-pharmaceuticals/two-test-positive-ghana-highly-infectious-marburg-virus-2022-07-07|work=Reuters|access-date=10 July 2022|archive-date=8 July 2022|archive-url=https://web.archive.org/web/20220708153808/https://www.reuters.com/business/healthcare-pharmaceuticals/two-test-positive-ghana-highly-infectious-marburg-virus-2022-07-07/|url-status=live}} Two positive cases were reported by Ghana on 8 July. After confirmation by the World Health Organization, it is the first such outbreak in Ghana. Two men aged 26 and 51 years old were infected with the disease and both cases resulted in fatalities. An additional case was identified, bringing the total to three.{{Cite tweet |user=_GHSofficial |number=1552716814974689280 |title=Update on Marburg Virus Disease Outbreak in Ghana}}
Background
{{Main|Marburg virus disease}}
Marburg virus disease (MVD) is a highly virulent, epidemic-prone disease, associated with a high case-fatality ratio of 24–90%. In the early phase of the disease, it is hard to distinguish the disease from other diseases. There are no specific treatments or vaccine against the Marburg virus, though supportive care increases the likelihood of survival.{{cite news|date=10 August 2021|title=Marburg virus disease – Guinea|publisher=World Health Organization|url=https://www.who.int/emergencies/disease-outbreak-news/item/2021-DON331|access-date=10 August 2021|archive-date=10 August 2021|archive-url=https://web.archive.org/web/20210810003213/https://www.who.int/emergencies/disease-outbreak-news/item/2021-DON331|url-status=live}}{{cite web |title=Guinea declares end of Marburg virus outbreak |url=https://www.cnn.com/2021/09/17/africa/guinea-marburg-virus-over-intl/index.html |website=CNN |date=17 September 2021 |access-date=18 September 2021 |archive-date=18 September 2021 |archive-url=https://web.archive.org/web/20210918011900/https://www.cnn.com/2021/09/17/africa/guinea-marburg-virus-over-intl/index.html |url-status=live }} Fourteen outbreaks of the disease have been reported since 1967, when it was first detected, mostly in sub-Saharan Africa.{{Cite news |last1=Paweska |first1=Janusz |last2=Groome |first2=Michelle J. |date=12 September 2021 |title=Marburg in Guinea: the value of lessons from managing other haemorrhagic outbreaks |language=en |work=The Conversation |url=https://theconversation.com/marburg-in-guinea-the-value-of-lessons-from-managing-other-haemorrhagic-outbreaks-167392 |access-date=3 December 2021 |archive-date=3 December 2021 |archive-url=https://web.archive.org/web/20211203073959/https://theconversation.com/marburg-in-guinea-the-value-of-lessons-from-managing-other-haemorrhagic-outbreaks-167392 |url-status=live }}
The disease's usual reservoir species is the Egyptian fruit bat.{{cite news |last1=Markotter |first1=Wanda |title=The first human case of Marburg virus in West Africa is no surprise: here's why |url=https://theconversation.com/the-first-human-case-of-marburg-virus-in-west-africa-is-no-surprise-heres-why-166694 |access-date=3 December 2021 |work=The Conversation |date=20 August 2021 |language=en |archive-date=3 December 2021 |archive-url=https://web.archive.org/web/20211203073957/https://theconversation.com/the-first-human-case-of-marburg-virus-in-west-africa-is-no-surprise-heres-why-166694 |url-status=live }} Among humans, it is transmitted via direct contact with the bodily fluids of an infected individual.{{cite journal |last1=Aborode |first1=Abdullahi Tunde |last2=Wireko |first2=Andrew Awuah |last3=Bel-Nono |first3=Katerina Namaal |last4=Quarshie |first4=Louisa Sowah |last5=Allison |first5=Mariam |last6=Bello |first6=Munira Aminu |title=Marburg virus amidst COVID-19 pandemic in Guinea: Fighting within the looming cases |journal=The International Journal of Health Planning and Management |year=2021 |volume=37 |issue=1 |pages=553–555 |doi=10.1002/hpm.3332 |pmid=34525245 |pmc=8653112 |doi-access=free }}
Outbreak
Two individuals in the southern Ashanti Region of Ghana developed Marburg disease-like symptoms—including diarrhea, fever, nausea, and emesis—before dying in a hospital. The two victims were unrelated. Tests for Marburg virus conducted in Ghana were positive for both. This was revealed on 8 July 2022. According to the United Nations, the cases, if confirmed by the World Health Organization (WHO), will be the first such cases of Marburg in Ghana.{{cite web|url=https://news.un.org/en/story/2022/07/1122242|title=Ghana prepares for possible first-ever Marburg virus outbreak|website=UN News|date=8 July 2022 |publisher=United Nations|access-date=|archive-date=9 July 2022|archive-url=https://web.archive.org/web/20220709194058/https://news.un.org/en/story/2022/07/1122242|url-status=live}} Samples have been sent to the Pasteur Institute of Dakar, Senegal for further testing.{{cite news|last=Associated Press|date=8 July 2022|title=WHO: Ghana reports 2 suspected cases of Marburg virus|url=https://abcnews.go.com/Health/wireStory/ghana-reports-suspected-cases-marburg-virus-86435554|work=ABC News|access-date=10 July 2022|archive-date=9 July 2022|archive-url=https://web.archive.org/web/20220709162621/https://abcnews.go.com/Health/wireStory/ghana-reports-suspected-cases-marburg-virus-86435554|url-status=live}} Two more cases of the virus were confirmed in Ghana by the WHO on 27 July 2022, with a third victim succumbing to the virus.{{Cite news |date=27 July 2022 |title=WHO confirms two more Marburg virus cases in Ghana, says official |language=en |work=National Post |url=https://nationalpost.com/pmn/health-pmn/who-confirms-two-more-marburg-virus-cases-in-ghana-says-official-2 |access-date=27 July 2022}}
The outbreak was confirmed by the World Health Organization on 17 July 2022, making it the first such outbreak in Ghana.{{cite news|date=17 July 2022|title=Ghana confirms its first outbreak of highly infectious Marburg virus|url=https://www.reuters.com/world/africa/ghana-confirms-two-cases-highly-infectious-marburg-virus-2022-07-17/|work=Reuters|location=Dakar|publisher=Thomson Reuters|publication-place=Toronto|access-date=18 July 2022|archive-date=18 July 2022|archive-url=https://web.archive.org/web/20220718122312/https://www.reuters.com/world/africa/ghana-confirms-two-cases-highly-infectious-marburg-virus-2022-07-17/|url-status=live}} The outbreak follows another that occurred in Guinea the previous year.{{cite news|date=8 July 2022|title=Two test positive in Ghana for highly infectious Marburg virus|url=https://www.aljazeera.com/news/2022/7/8/two-test-positive-in-ghana-for-highly-infectious-marburg-virus|work=Al Jazeera|access-date=18 July 2022|archive-date=18 July 2022|archive-url=https://web.archive.org/web/20220718093837/https://www.aljazeera.com/news/2022/7/8/two-test-positive-in-ghana-for-highly-infectious-marburg-virus|url-status=live}}