2022 Italian Open – Men's singles

{{Infobox tennis tournament event|2022|Italian Open|

| champ = {{flagicon|SRB}} Novak Djokovic

| runner = {{flagicon|GRE}} Stefanos Tsitsipas

| score = 6–0, 7–6^(7–5)

|draw = 56 (7{{abbr| Q | Qualifiers}} / 4{{abbr| WC | Wild cards}})

| seeds = 16

}}

Novak Djokovic defeated Stefanos Tsitsipas in the final, 6–0, 7–6^(7–5) to win the men's singles tennis title at the 2022 Italian Open.{{cite web|url=https://www.atptour.com/en/news/djokovic-tsitsipas-rome-2022-sunday|title=Djokovic Downs Tsitsipas For Rome Title|date=15 May 2022|publisher=Association of Tennis Professionals}} It was his sixth Italian Open title and record-extending 38th Masters 1000 title overall. Djokovic did not lose a set during the tournament, and won his 1000th ATP Tour-level career match against Casper Ruud in the semifinals.{{cite web|url=https://www.atptour.com/en/news/djokovic-ruud-rome-2022-sf|title=Djokovic Scores 1,000th Career Win To Reach Rome Final|date=14 May 2022|publisher=Association of Tennis Professionals}}

Rafael Nadal was the defending champion,{{Cite web|date=16 May 2021|title=Nadal Fights Past Djokovic For Record-Extending 10th Rome Crown|url=https://www.atptour.com/en/news/djokovic-nadal-rome-2021-sunday-final|url-status=live|archive-url=https://web.archive.org/web/20220327183553/https://www.atptour.com/en/news/djokovic-nadal-rome-2021-sunday-final|archive-date=27 March 2022|access-date=27 April 2022|publisher=Association of Tennis Professionals}} but lost in the third round to Denis Shapovalov.

Djokovic and Daniil Medvedev were in contention for the ATP No. 1 singles ranking. Djokovic retained the top position by reaching the semifinals.

Seeds

The top eight seeds received a bye into the second round.

{{columns-list|colwidth=30em|

{{seeds|1|1}} {{flagicon|SRB}} Novak Djokovic (champion)

{{seeds|2|4}} {{flagicon|GER}} Alexander Zverev (semifinals)

{{seeds|3|2}} {{flagicon|ESP}} Rafael Nadal (third round)

{{seeds|4|3}} {{flagicon|GRE}} Stefanos Tsitsipas (final)

{{seeds|5|2}} {{flagicon|NOR}} Casper Ruud (semifinals)

{{seeds|6|3}} {{flagicon|}} Andrey Rublev (second round)

{{seeds|7}} {{flagicon|ESP}} Carlos Alcaraz (withdrew)

{{seeds|8|1}} {{flagicon|CAN}} Félix Auger-Aliassime (quarterfinals)

{{seeds|9|4}} {{flagicon|GBR}} Cameron Norrie (second round)

{{seeds|10|3}} {{flagicon|ITA}} Jannik Sinner (quarterfinals)

{{seeds|11|2}} {{flagicon|POL}} Hubert Hurkacz (first round)

{{seeds|12|1}} {{flagicon|ARG}} Diego Schwartzman (second round)

{{seeds|13|2}} {{flagicon|CAN}} Denis Shapovalov (quarterfinals)

{{seeds|14|1}} {{flagicon|USA}} Reilly Opelka (first round)

{{seeds|15|3}} {{flagicon|ESP}} Pablo Carreño Busta (second round)

{{seeds|16}} {{flagicon|ESP}} Roberto Bautista Agut (withdrew)

}}

Draw

=Finals=

{{8TeamBracket-Tennis3

| RD1=Quarterfinals

| RD2=Semifinals

| RD3=Final

| team-width=175

| RD1-seed1=1

| RD1-team1={{flagicon|SRB}} Novak Djokovic

| RD1-score1-1=7

| RD1-score1-2=7⁷

| RD1-score1-3=

| RD1-seed2=8

| RD1-team2={{flagicon|CAN}} Félix Auger-Aliassime

| RD1-score2-1=5

| RD1-score2-2=6¹

| RD1-score2-3=

| RD1-seed3=13

| RD1-team3={{flagicon|CAN}} Denis Shapovalov

| RD1-score3-1=6⁷

| RD1-score3-2=5

| RD1-score3-3=

| RD1-seed4=5

| RD1-team4={{flagicon|NOR}} Casper Ruud

| RD1-score4-1=7⁹

| RD1-score4-2=7

| RD1-score4-3=

| RD1-seed5=10

| RD1-team5={{flagicon|ITA}} Jannik Sinner

| RD1-score5-1=6⁵

| RD1-score5-2=2

| RD1-score5-3=

| RD1-seed6=4

| RD1-team6={{flagicon|GRE}} Stefanos Tsitsipas

| RD1-score6-1=7⁷

| RD1-score6-2=6

| RD1-score6-3=

| RD1-seed7=

| RD1-team7={{flagicon|CHI}} Cristian Garín

| RD1-score7-1=5

| RD1-score7-2=2

| RD1-score7-3=

| RD1-seed8=2

| RD1-team8={{flagicon|GER}} Alexander Zverev

| RD1-score8-1=7

| RD1-score8-2=6

| RD1-score8-3=

| RD2-seed1=1

| RD2-team1={{flagicon|SRB}} Novak Djokovic

| RD2-score1-1=6

| RD2-score1-2=6

| RD2-score1-3=

| RD2-seed2=5

| RD2-team2={{flagicon|NOR}} Casper Ruud

| RD2-score2-1=4

| RD2-score2-2=3

| RD2-score2-3=

| RD2-seed3=4

| RD2-team3={{flagicon|GRE}} Stefanos Tsitsipas

| RD2-score3-1=4

| RD2-score3-2=6

| RD2-score3-3=6

| RD2-seed4=2

| RD2-team4={{flagicon|GER}} Alexander Zverev

| RD2-score4-1=6

| RD2-score4-2=3

| RD2-score4-3=3

| RD3-seed1=1

| RD3-team1={{flagicon|SRB}} Novak Djokovic

| RD3-score1-1=6

| RD3-score1-2=7⁷

| RD3-score1-3=

| RD3-seed2=4

| RD3-team2={{flagicon|GRE}} Stefanos Tsitsipas

| RD3-score2-1=0

| RD3-score2-2=6⁵

| RD3-score2-3=

}}

=Top half=

==Section 1==

{{16TeamBracket-Compact-Tennis3-Byes

| RD1=First round

| RD2=Second round

| RD3=Third round

| RD4=Quarterfinals

| RD1-seed03=

| RD1-team03={{flagicon|RSA}} L Harris

| RD1-score03-1=6

| RD1-score03-2=3

| RD1-score03-3=6⁷

| RD1-seed04=

| RD1-team04={{flagicon|}} A Karatsev

| RD1-score04-1=3

| RD1-score04-2=6

| RD1-score04-3=7⁹

| RD1-seed05=Q

| RD1-team05={{flagicon|SRB}} L Đere

| RD1-score05-1=6

| RD1-score05-2=6³

| RD1-score05-3=6

| RD1-seed06=PR

| RD1-team06={{flagicon|CRO}} B Ćorić

| RD1-score06-1=2

| RD1-score06-2=7⁷

| RD1-score06-3=2

| RD1-seed07=PR

| RD1-team07={{flagicon|SUI}} S Wawrinka

| RD1-score07-1=3

| RD1-score07-2=7

| RD1-score07-3=6

| RD1-seed08=14

| RD1-team08={{flagicon|USA}} R Opelka

| RD1-score08-1=6

| RD1-score08-2=5

| RD1-score08-3=2

| RD1-seed09=12

| RD1-team09={{flagicon|ARG}} D Schwartzman

| RD1-score09-1=6

| RD1-score09-2=3

| RD1-score09-3=7⁷

| RD1-seed10=

| RD1-team10={{flagicon|SRB}} M Kecmanović

| RD1-score10-1=2

| RD1-score10-2=6

| RD1-score10-3=6³

| RD1-seed11=

| RD1-team11={{flagicon|KAZ}} A Bublik

| RD1-score11-1=6

| RD1-score11-2=4

| RD1-score11-3=3

| RD1-seed12=LL

| RD1-team12={{flagicon|USA}} M Giron

| RD1-score12-1=3

| RD1-score12-2=6

| RD1-score12-3=6

| RD1-seed13=

| RD1-team13={{flagicon|ESP}} A Davidovich Fokina

| RD1-score13-1=6

| RD1-score13-2=4

| RD1-score13-3=6

| RD1-seed14=

| RD1-team14={{flagicon|}} I Ivashka

| RD1-score14-1=2

| RD1-score14-2=6

| RD1-score14-3=4

| RD2-seed01=1

| RD2-team01={{flagicon|SRB}} N Djokovic

| RD2-score01-1=6

| RD2-score01-2=6

| RD2-score01-3=

| RD2-seed02=

| RD2-team02={{flagicon|}} A Karatsev

| RD2-score02-1=3

| RD2-score02-2=2

| RD2-score02-3=

| RD2-seed03=Q

| RD2-team03={{flagicon|SRB}} L Đere

| RD2-score03-1=6⁸

| RD2-score03-2=6

| RD2-score03-3=4

| RD2-seed04=PR

| RD2-team04={{flagicon|SUI}} S Wawrinka

| RD2-score04-1=7¹⁰

| RD2-score04-2=3

| RD2-score04-3=6

| RD2-seed05=12

| RD2-team05={{flagicon|ARG}} D Schwartzman

| RD2-score05-1=1

| RD2-score05-2=6⁴

| RD2-score05-3=

| RD2-seed06=LL

| RD2-team06={{flagicon|USA}} M Giron

| RD2-score06-1=6

| RD2-score06-2=7⁷

| RD2-score06-3=

| RD2-seed07=

| RD2-team07={{flagicon|ESP}} A Davidovich Fokina

| RD2-score07-1=6

| RD2-score07-2=6²

| RD2-score07-3=2

| RD2-seed08=8

| RD2-team08={{flagicon|CAN}} F Auger-Aliassime

| RD2-score08-1=4

| RD2-score08-2=7⁷

| RD2-score08-3=6

| RD3-seed01=1

| RD3-team01={{flagicon|SRB}} N Djokovic

| RD3-score01-1=6

| RD3-score01-2=6

| RD3-score01-3=

| RD3-seed02=PR

| RD3-team02={{flagicon|SUI}} S Wawrinka

| RD3-score02-1=2

| RD3-score02-2=2

| RD3-score02-3=

| RD3-seed03=LL

| RD3-team03={{flagicon|USA}} M Giron

| RD3-score03-1=3

| RD3-score03-2=2

| RD3-score03-3=

| RD3-seed04=8

| RD3-team04={{flagicon|CAN}} F Auger-Aliassime

| RD3-score04-1=6

| RD3-score04-2=6

| RD3-score04-3=

| RD4-seed01=1

| RD4-team01={{flagicon|SRB}} N Djokovic

| RD4-score01-1=7

| RD4-score01-2=7⁷

| RD4-score01-3=

| RD4-seed02=8

| RD4-team02={{flagicon|CAN}} F Auger-Aliassime

| RD4-score02-1=5

| RD4-score02-2=6¹

| RD4-score02-3=

}}

==Section 2==

{{16TeamBracket-Compact-Tennis3-Byes

| RD1=First round

| RD2=Second round

| RD3=Third round

| RD4=Quarterfinals

| RD1-seed03=Q

| RD1-team03={{flagicon|ARG}} F Cerúndolo

| RD1-score03-1=4

| RD1-score03-2=3

| RD1-score03-3=

| RD1-seed04=

| RD1-team04={{flagicon|USA}} J Isner

| RD1-score04-1=6

| RD1-score04-2=6

| RD1-score04-3=

| RD1-seed05=

| RD1-team05={{flagicon|GEO}} N Basilashvili

| RD1-score05-1=7⁷

| RD1-score05-2=6

| RD1-score05-3=

| RD1-seed06=

| RD1-team06={{flagicon|GBR}} D Evans

| RD1-score06-1=6²

| RD1-score06-2=2

| RD1-score06-3=

| RD1-seed07=

| RD1-team07={{flagicon|ITA}} L Sonego

| RD1-score07-1=6⁵

| RD1-score07-2=6

| RD1-score07-3=3

| RD1-seed08=13

| RD1-team08={{flagicon|CAN}} D Shapovalov

| RD1-score08-1=7⁷

| RD1-score08-2=3

| RD1-score08-3=6

| RD1-seed09=11

| RD1-team09={{flagicon|POL}} H Hurkacz

| RD1-score09-1=6⁸

| RD1-score09-2=6²

| RD1-score09-3=

| RD1-seed10=

| RD1-team10={{flagicon|BEL}} D Goffin

| RD1-score10-1=7¹⁰

| RD1-score10-2=7⁷

| RD1-score10-3=

| RD1-seed11=

| RD1-team11={{flagicon|USA}} J Brooksby

| RD1-score11-1=6

| RD1-score11-2=6

| RD1-score11-3=

| RD1-seed12=WC

| RD1-team12={{flagicon|ITA}} F Cobolli

| RD1-score12-1=3

| RD1-score12-2=4

| RD1-score12-3=

| RD1-seed13=

| RD1-team13={{flagicon|USA}} S Korda

| RD1-score13-1=4

| RD1-score13-2=1

| RD1-score13-3=

| RD1-seed14=

| RD1-team14={{flagicon|NED}} B van de Zandschulp

| RD1-score14-1=6

| RD1-score14-2=6

| RD1-score14-3=

| RD2-seed01=3

| RD2-team01={{flagicon|ESP}} R Nadal

| RD2-score01-1=6

| RD2-score01-2=6

| RD2-score01-3=

| RD2-seed02=

| RD2-team02={{flagicon|USA}} J Isner

| RD2-score02-1=3

| RD2-score02-2=1

| RD2-score02-3=

| RD2-seed03=

| RD2-team03={{flagicon|GEO}} N Basilashvili

| RD2-score03-1=4

| RD2-score03-2=6⁵

| RD2-score03-3=

| RD2-seed04=13

| RD2-team04={{flagicon|CAN}} D Shapovalov

| RD2-score04-1=6

| RD2-score04-2=7⁷

| RD2-score04-3=

| RD2-seed05=

| RD2-team05={{flagicon|BEL}} D Goffin

| RD2-score05-1=0

| RD2-score05-2=6¹

| RD2-score05-3=

| RD2-seed06=

| RD2-team06={{flagicon|USA}} J Brooksby

| RD2-score06-1=6

| RD2-score06-2=7⁷

| RD2-score06-3=

| RD2-seed07=

| RD2-team07={{flagicon|NED}} B van de Zandschulp

| RD2-score07-1=7⁷

| RD2-score07-2=2

| RD2-score07-3=4

| RD2-seed08=5

| RD2-team08={{flagicon|NOR}} C Ruud

| RD2-score08-1=6⁴

| RD2-score08-2=6

| RD2-score08-3=6

| RD3-seed01=3

| RD3-team01={{flagicon|ESP}} R Nadal

| RD3-score01-1=6

| RD3-score01-2=5

| RD3-score01-3=2

| RD3-seed02=13

| RD3-team02={{flagicon|CAN}} D Shapovalov

| RD3-score02-1=1

| RD3-score02-2=7

| RD3-score02-3=6

| RD3-seed03=

| RD3-team03={{flagicon|USA}} J Brooksby

| RD3-score03-1=3

| RD3-score03-2=4

| RD3-score03-3=

| RD3-seed04=5

| RD3-team04={{flagicon|NOR}} C Ruud

| RD3-score04-1=6

| RD3-score04-2=6

| RD3-score04-3=

| RD4-seed01=13

| RD4-team01={{flagicon|CAN}} D Shapovalov

| RD4-score01-1=6⁷

| RD4-score01-2=5

| RD4-score01-3=

| RD4-seed02=5

| RD4-team02={{flagicon|NOR}} C Ruud

| RD4-score02-1=7⁹

| RD4-score02-2=7

| RD4-score02-3=

}}

=Bottom half=

==Section 3==

{{16TeamBracket-Compact-Tennis3-Byes

| RD1=First round

| RD2=Second round

| RD3=Third round

| RD4=Quarterfinals

| RD1-seed03=

| RD1-team03={{flagicon|SRB}} F Krajinović

| RD1-score03-1=7⁹

| RD1-score03-2=7⁷

| RD1-score03-3=

| RD1-seed04=

| RD1-team04={{flagicon|USA}} F Tiafoe

| RD1-score04-1=6⁷

| RD1-score04-2=6⁴

| RD1-score04-3=

| RD1-seed05=

| RD1-team05={{flagicon|ITA}} F Fognini

| RD1-score05-1=6

| RD1-score05-2=7⁷

| RD1-score05-3=

| RD1-seed06=PR

| RD1-team06={{flagicon|AUT}} D Thiem

| RD1-score06-1=4

| RD1-score06-2=6⁵

| RD1-score06-3=

| RD1-seed07=

| RD1-team07={{flagicon|ESP}} P Martínez

| RD1-score07-1=4

| RD1-score07-2=3

| RD1-score07-3=

| RD1-seed08=10

| RD1-team08={{flagicon|ITA}} J Sinner

| RD1-score08-1=6

| RD1-score08-2=6

| RD1-score08-3=

| RD1-seed09=15

| RD1-team09={{flagicon|ESP}} P Carreño Busta

| RD1-score09-1=6

| RD1-score09-2=6

| RD1-score09-3=

| RD1-seed10=

| RD1-team10={{flagicon|ARG}} F Delbonis

| RD1-score10-1=3

| RD1-score10-2=2

| RD1-score10-3=

| RD1-seed11=

| RD1-team11={{flagicon|}} K Khachanov

| RD1-score11-1=6

| RD1-score11-2=6

| RD1-score11-3=

| RD1-seed12=Q

| RD1-team12={{flagicon|ITA}} G Zeppieri

| RD1-score12-1=3

| RD1-score12-2=4

| RD1-score12-3=

| RD1-seed13=

| RD1-team13={{flagicon|BUL}} G Dimitrov

| RD1-score13-1=6

| RD1-score13-2=6

| RD1-score13-3=

| RD1-seed14=Q

| RD1-team14={{flagicon|USA}} B Nakashima

| RD1-score14-1=3

| RD1-score14-2=4

| RD1-score14-3=

| RD2-seed01=6

| RD2-team01={{flagicon|}} A Rublev

| RD2-score01-1=2

| RD2-score01-2=4

| RD2-score01-3=

| RD2-seed02=

| RD2-team02={{flagicon|SRB}} F Krajinović

| RD2-score02-1=6

| RD2-score02-2=6

| RD2-score02-3=

| RD2-seed03=

| RD2-team03={{flagicon|ITA}} F Fognini

| RD2-score03-1=2

| RD2-score03-2=6

| RD2-score03-3=3

| RD2-seed04=10

| RD2-team04={{flagicon|ITA}} J Sinner

| RD2-score04-1=6

| RD2-score04-2=3

| RD2-score04-3=6

| RD2-seed05=15

| RD2-team05={{flagicon|ESP}} P Carreño Busta

| RD2-score05-1=4

| RD2-score05-2=6

| RD2-score05-3=1

| RD2-seed06=

| RD2-team06={{flagicon|}} K Khachanov

| RD2-score06-1=6

| RD2-score06-2=2

| RD2-score06-3=6

| RD2-seed07=

| RD2-team07={{flagicon|BUL}} G Dimitrov

| RD2-score07-1=3

| RD2-score07-2=7

| RD2-score07-3=6⁴

| RD2-seed08=4

| RD2-team08={{flagicon|GRE}} S Tsitsipas

| RD2-score08-1=6

| RD2-score08-2=5

| RD2-score08-3=7⁷

| RD3-seed01=

| RD3-team01={{flagicon|SRB}} F Krajinović

| RD3-score01-1=2

| RD3-score01-2=6⁶

| RD3-score01-3=

| RD3-seed02=10

| RD3-team02={{flagicon|ITA}} J Sinner

| RD3-score02-1=6

| RD3-score02-2=7⁸

| RD3-score02-3=

| RD3-seed03=

| RD3-team03={{flagicon|}} K Khachanov

| RD3-score03-1=6

| RD3-score03-2=0

| RD3-score03-3=3

| RD3-seed04=4

| RD3-team04={{flagicon|GRE}} S Tsitsipas

| RD3-score04-1=4

| RD3-score04-2=6

| RD3-score04-3=6

| RD4-seed01=10

| RD4-team01={{flagicon|ITA}} J Sinner

| RD4-score01-1=6⁵

| RD4-score01-2=2

| RD4-score01-3=

| RD4-seed02=4

| RD4-team02={{flagicon|GRE}} S Tsitsipas

| RD4-score02-1=7⁷

| RD4-score02-2=6

| RD4-score02-3=

}}

==Section 4==

{{16TeamBracket-Compact-Tennis3-Byes

| RD1=First round

| RD2=Second round

| RD3=Third round

| RD4=Quarterfinals

| RD1-seed03=WC

| RD1-team03={{flagicon|ITA}} F Passaro

| RD1-score03-1=3

| RD1-score03-2=2

| RD1-score03-3=

| RD1-seed04=

| RD1-team04={{flagicon|CHI}} C Garín

| RD1-score04-1=6

| RD1-score04-2=6

| RD1-score04-3=

| RD1-seed05=

| RD1-team05={{flagicon|CRO}} M Čilić

| RD1-score05-1=6

| RD1-score05-2=6

| RD1-score05-3=

| RD1-seed06=WC

| RD1-team06={{flagicon|ITA}} M Arnaldi

| RD1-score06-1=1

| RD1-score06-2=4

| RD1-score06-3=

| RD1-seed07=WC

| RD1-team07={{flagicon|ITA}} L Nardi

| RD1-score07-1=4

| RD1-score07-2=4

| RD1-score07-3=

| RD1-seed08=9

| RD1-team08={{flagicon|GBR}} C Norrie

| RD1-score08-1=6

| RD1-score08-2=6

| RD1-score08-3=

| RD1-seed09=Q

| RD1-team09={{flagicon|SRB}} D Lajović

| RD1-score09-1=4

| RD1-score09-2=1

| RD1-score09-3=

| RD1-seed10=

| RD1-team10={{flagicon|AUS}} A de Minaur

| RD1-score10-1=6

| RD1-score10-2=6

| RD1-score10-3=

| RD1-seed11=

| RD1-team11={{flagicon|ESP}} A Ramos Viñolas

| RD1-score11-1=4

| RD1-score11-2=4

| RD1-score11-3=

| RD1-seed12=

| RD1-team12={{flagicon|USA}} T Paul

| RD1-score12-1=6

| RD1-score12-2=6

| RD1-score12-3=

| RD1-seed13=Q

| RD1-team13={{flagicon|NED}} T Griekspoor

| RD1-score13-1=3

| RD1-score13-2=7⁹

| RD1-score13-3=2

| RD1-seed14=Q

| RD1-team14={{flagicon|ARG}} S Báez

| RD1-score14-1=6

| RD1-score14-2=6⁷

| RD1-score14-3=6

| RD2-seed01=LL

| RD2-team01={{flagicon|FIN}} E Ruusuvuori

| RD2-score01-1=4

| RD2-score01-2=4

| RD2-score01-3=

| RD2-seed02=

| RD2-team02={{flagicon|CHI}} C Garín

| RD2-score02-1=6

| RD2-score02-2=6

| RD2-score02-3=

| RD2-seed03=

| RD2-team03={{flagicon|CRO}} M Čilić

| RD2-score03-1=5

| RD2-score03-2=6

| RD2-score03-3=6

| RD2-seed04=9

| RD2-team04={{flagicon|GBR}} C Norrie

| RD2-score04-1=7

| RD2-score04-2=2

| RD2-score04-3=1

| RD2-seed05=

| RD2-team05={{flagicon|AUS}} A de Minaur

| RD2-score05-1=7

| RD2-score05-2=6

| RD2-score05-3=

| RD2-seed06=

| RD2-team06={{flagicon|USA}} T Paul

| RD2-score06-1=5

| RD2-score06-2=4

| RD2-score06-3=

| RD2-seed07=Q

| RD2-team07={{flagicon|ARG}} S Báez

| RD2-score07-1=6⁶

| RD2-score07-2=3

| RD2-score07-3=

| RD2-seed08=2

| RD2-team08={{flagicon|GER}} A Zverev

| RD2-score08-1=7⁸

| RD2-score08-2=6

| RD2-score08-3=

| RD3-seed01=

| RD3-team01={{flagicon|CHI}} C Garín

| RD3-score01-1=6

| RD3-score01-2=4

| RD3-score01-3=6

| RD3-seed02=

| RD3-team02={{flagicon|CRO}} M Čilić

| RD3-score02-1=3

| RD3-score02-2=6

| RD3-score02-3=4

| RD3-seed03=

| RD3-team03={{flagicon|AUS}} A de Minaur

| RD3-score03-1=3

| RD3-score03-2=6⁵

| RD3-score03-3=

| RD3-seed04=2

| RD3-team04={{flagicon|GER}} A Zverev

| RD3-score04-1=6

| RD3-score04-2=7⁷

| RD3-score04-3=

| RD4-seed01=

| RD4-team01={{flagicon|CHI}} C Garín

| RD4-score01-1=5

| RD4-score01-2=2

| RD4-score01-3=

| RD4-seed02=2

| RD4-team02={{flagicon|GER}} A Zverev

| RD4-score02-1=7

| RD4-score02-2=6

| RD4-score02-3=

}}

Seeded players

The following are the seeded players. Seedings are based on ATP rankings as of 2 May 2022. Rankings and points before are as of 9 May 2022.

As a result of special ranking adjustment rules due to the COVID-19 pandemic, players are defending the higher of (i) their points from the 2021 tournament or (ii) the remaining 50% of their points from the 2020 tournament. Those points were not mandatory and are included in the table below only if they counted towards the player's ranking as of May 9, 2022. Players who are not defending points from the 2021 or 2020 tournaments will instead have their 19th best result replaced by their points from the 2022 tournament.

class="wikitable sortable"

! style="width:30px;" |Seed

! style="width:30px;" |Rank

! style="width:185px;" |Player

! style="width:75px;" |Points before

! style="width:75px;" |Points defending (or 19th best result)^†

! style="width:75px;" |Points won

! style="width:75px;" |Points after

! style="width:320px;" |Status

bgcolor=#cfc

| style="text-align:center;" | 1

| {{flagicon|SRB}} Novak Djokovic

| style="text-align:center;" | 8,260

| style="text-align:center;" | 600

| style="text-align:center;" | 1,000

| style="text-align:center;" | 8,660

| Champion, defeated {{flagicon|GRE}} Stefanos Tsitsipas [4]

style="text-align:center;" | 2

| style="text-align:center;" | 3

| {{flagicon|GER}} Alexander Zverev

| style="text-align:center;" | 7,020

| style="text-align:center;" | 180

| style="text-align:center;" | 360

| style="text-align:center;" | 7,200

| Semifinals lost to {{flagicon|GRE}} Stefanos Tsitsipas [4]

style="text-align:center;" | 3

| style="text-align:center;" | 4

| {{flagicon|ESP}} Rafael Nadal

| style="text-align:center;" | 6,435

| style="text-align:center;" | 1,000

| style="text-align:center;" | 90

| style="text-align:center;" | 5,525

| Third round lost to {{flagicon|CAN}} Denis Shapovalov [13]

bgcolor=#fcc

| style="text-align:center;" | 4

| style="text-align:center;" | 5

| {{flagicon|GRE}} Stefanos Tsitsipas

| style="text-align:center;" | 5,750

| style="text-align:center;" | 180

| style="text-align:center;" | 600

| style="text-align:center;" | 6,170

| Runner-up, lost to {{flagicon|SRB}} Novak Djokovic [1]

style="text-align:center;" | 5

| style="text-align:center;" | 10

| {{flagicon|NOR}} Casper Ruud

| style="text-align:center;" | 3,760

| style="text-align:center;" | 180

| style="text-align:center;" | 360

| style="text-align:center;" | 3,940

| Semifinals lost to {{flagicon|SRB}} Novak Djokovic [1]

style="text-align:center;" | 6

| style="text-align:center;" | 7

| {{flagicon

} Andrey Rublev

| style="text-align:center;" | 4,115

| style="text-align:center;" | 180

| style="text-align:center;" | 10

| style="text-align:center;" | 3,945

| Second round lost to {{flagicon|SRB}} Filip Krajinović

| style="text-align:center;" | 7

| style="text-align:center;" | 6

| ~~{{flagicon|ESP}} Carlos Alcaraz~~

| style="text-align:center;" | 4,773

| style="text-align:center;" | (3)

| style="text-align:center;" | 0

| style="text-align:center;" | 4,770

| Withdrew due to ankle injury

| style="text-align:center;" | 8

| style="text-align:center;" | 9

| {{flagicon|CAN}} Félix Auger-Aliassime

| style="text-align:center;" | 3,760

| style="text-align:center;" | 90

| style="text-align:center;" | 180

| style="text-align:center;" | 3,850

| Quarterfinals lost to {{flagicon|SRB}} Novak Djokovic [1]

| style="text-align:center;" | 9

| style="text-align:center;" | 11

| {{flagicon|GBR}} Cameron Norrie

| style="text-align:center;" | 3,380

| style="text-align:center;" | 70

| style="text-align:center;" | 45

| style="text-align:center;" | 3,355

| Second round lost to {{flagicon|CRO}} Marin Čilić

| style="text-align:center;" | 10

| style="text-align:center;" | 13

| {{flagicon|ITA}} Jannik Sinner

| style="text-align:center;" | 3,060

| style="text-align:center;" | 45

| style="text-align:center;" | 180

| style="text-align:center;" | 3,195

| Quarterfinals lost to {{flagicon|GRE}} Stefanos Tsitsipas [4]

| style="text-align:center;" | 11

| style="text-align:center;" | 12

| {{flagicon|POL}} Hubert Hurkacz

| style="text-align:center;" | 3,130

| style="text-align:center;" | 45

| style="text-align:center;" | 10

| style="text-align:center;" | 3,095

| First round lost to {{flagicon|BEL}} David Goffin

| style="text-align:center;" | 12

| style="text-align:center;" | 15

| {{flagicon|ARG}} Diego Schwartzman

| style="text-align:center;" | 2,760

| style="text-align:center;" | 300

| style="text-align:center;" | 45

| style="text-align:center;" | 2,505

| Second round lost to {{flagicon|USA}} Marcos Giron [LL]

| style="text-align:center;" | 13

| style="text-align:center;" | 16

| {{flagicon|CAN}} Denis Shapovalov

| style="text-align:center;" | 2,671

| style="text-align:center;" | 180

| style="text-align:center;" | 2,671

| Quarterfinals lost to {{flagicon|NOR}} Casper Ruud [5]

| style="text-align:center;" | 14

| style="text-align:center;" | 17

| {{flagicon|USA}} Reilly Opelka

| style="text-align:center;" | 2,440

| style="text-align:center;" | 360

| style="text-align:center;" | 10

| style="text-align:center;" | 2,090

| First round lost to {{flagicon|SUI}} Stan Wawrinka [PR]

| style="text-align:center;" | 15

| style="text-align:center;" | 18

| {{flagicon|ESP}} Pablo Carreño Busta

| style="text-align:center;" | 2,135

| style="text-align:center;" | 45

| style="text-align:center;" | 2,135

| Second round lost to {{flagicon|}} Karen Khachanov

| style="text-align:center;" | 16

| style="text-align:center;" | 19

| ~~{{flagicon|ESP}} Roberto Bautista Agut~~

| style="text-align:center;" | 1,993

| style="text-align:center;" | 90

| style="text-align:center;" | 0

| style="text-align:center;" | 1,903

| Withdrew due to right wrist injury

† This column shows either (a) the higher of the player's points from the 2021 tournament or 50% of his points from the 2020 tournament, or (b) his 19th best result (shown in brackets). Only ranking points counting towards the player's ranking as of May 9, 2022, are reflected in the column.

= Withdrawn players =

The following players would have been seeded, but withdrew before the tournament began.

class="wikitable sortable"
Rank ! style="width:185px;" \|Player ! Points before ! style="width:75px;" \|Points defending ! Points after ! Withdrawal reason
style="text-align:center;" \| 2 \| {{flagicon

class="wikitable sortable"

Rank

! style="width:185px;" |Player

! Points before

! style="width:75px;" |Points defending

! Points after

! Withdrawal reason

style="text-align:center;" | 2

| {{flagicon

} Daniil Medvedev

| style="text-align:center;" | 7,990

| style="text-align:center;" | 10

| style="text-align:center;" | 7,980

| Hernia surgery

| style="text-align:center;" | 8

| {{flagicon|ITA}} Matteo Berrettini

| style="text-align:center;" | 3,895

| style="text-align:center;" | 90

| style="text-align:center;" | 3,805

| Right hand injury

| style="text-align:center;" | 14

| {{flagicon|USA}} Taylor Fritz

| style="text-align:center;" | 2,965

| style="text-align:center;" | 45

| style="text-align:center;" | 2,920

| Left foot injury

Other entry information

=Wildcards=

{{columns-list|colwidth=30em|

{{flagicon|ITA}} Matteo Arnaldi
{{flagicon|ITA}} Flavio Cobolli
{{flagicon|ITA}} Luca Nardi
{{flagicon|ITA}} Francesco Passaro

}}

=Protected ranking=

{{columns-list|colwidth=30em|

{{flagicon|CRO}} Borna Ćorić
{{flagicon|AUT}} Dominic Thiem
{{flagicon|SUI}} Stan Wawrinka

}}

=Withdrawals=

{{columns-list|colwidth=30em|

{{flagicon|ESP}} Carlos Alcaraz → replaced by {{flagicon|FIN}} Emil Ruusuvuori
{{flagicon|ESP}} Roberto Bautista Agut → replaced by {{flagicon|USA}} Marcos Giron
{{flagicon|ITA}} Matteo Berrettini → replaced by {{flagicon|USA}} Sebastian Korda
{{flagicon|USA}} Taylor Fritz → replaced by {{flagicon|ESP}} Pedro Martínez
{{flagicon|}} Daniil Medvedev → replaced by {{flagicon|}} Ilya Ivashka
{{flagicon|FRA}} Gaël Monfils → replaced by {{flagicon|ESP}} Alejandro Davidovich Fokina

}}

Qualifying

=Seeds=

{{columns-list|colwidth=30em|

{{flagicon|ARG}} Sebastián Báez (qualified)
{{flagicon|DEN}} Holger Rune (first round)
{{flagicon|FRA}} Ugo Humbert (first round)
{{flagicon|SVK}} Alex Molčan (first round)
{{flagicon|ARG}} Francisco Cerúndolo (qualified)
{{flagicon|HUN}} Márton Fucsovics (qualifying competition, retired)
{{flagicon|USA}} Marcos Giron (qualifying competition, lucky loser)
{{flagicon|SRB}} Laslo Đere (qualified)
{{flagicon|USA}} Mackenzie McDonald (first round)
{{flagicon|NED}} Tallon Griekspoor (qualified)
{{flagicon|ARG}} Federico Coria (first round)
{{flagicon|FIN}} Emil Ruusuvuori (qualifying competition, lucky loser)
{{flagicon|FRA}} Benoît Paire (first round)
{{flagicon|USA}} Maxime Cressy (qualifying competition)

}}

=Qualifiers=

{{columns-list|colwidth=30em|

{{flagicon|ARG}} Sebastián Báez
{{flagicon|SRB}} Laslo Đere
{{flagicon|USA}} Brandon Nakashima
{{flagicon|ITA}} Giulio Zeppieri
{{flagicon|ARG}} Francisco Cerúndolo
{{flagicon|SRB}} Dušan Lajović
{{flagicon|NED}} Tallon Griekspoor

}}

=Lucky losers=

{{columns-list|colwidth=30em|

{{flagicon|USA}} Marcos Giron
{{flagicon|FIN}} Emil Ruusuvuori

}}

=Draw=

==First qualifier==

{{4TeamBracket-Tennis3

| RD1=First round

| RD2=Qualifying competition

| team-width=175

| RD1-seed1=1

| RD1-team1={{flagicon|ARG}} Sebastián Báez

| RD1-score1-1=6

| RD1-score1-2=6

| RD1-score1-3=

| RD1-seed2=

| RD1-team2={{flagicon|KOR}} Kwon Soon-woo

| RD1-score2-1=4

| RD1-score2-2=4

| RD1-score2-3=

| RD1-seed3=WC

| RD1-team3={{flagicon|ITA}} Giovanni Fonio

| RD1-score3-1=4

| RD1-score3-2=7⁹

| RD1-score3-3=3

| RD1-seed4=12

| RD1-team4={{flagicon|FIN}} Emil Ruusuvuori

| RD1-score4-1=6

| RD1-score4-2=6⁷

| RD1-score4-3=6

| RD2-seed1=1

| RD2-team1={{flagicon|ARG}} Sebastián Báez

| RD2-score1-1=6³

| RD2-score1-2=6

| RD2-score1-3=7

| RD2-seed2=12

| RD2-team2={{flagicon|FIN}} Emil Ruusuvuori

| RD2-score2-1=7⁷

| RD2-score2-2=4

| RD2-score2-3=5

}}

==Second qualifier==

{{4TeamBracket-Tennis3

| RD1=First round

| RD2=Qualifying competition

| team-width=175

| RD1-seed1=2

| RD1-team1={{flagicon|DEN}} Holger Rune

| RD1-score1-1=1

| RD1-score1-2=6

| RD1-score1-3=3

| RD1-seed2=

| RD1-team2={{flagicon|BOL}} Hugo Dellien

| RD1-score2-1=6

| RD1-score2-2=1

| RD1-score2-3=6

| RD1-seed3=

| RD1-team3={{flagicon|AUS}} Thanasi Kokkinakis

| RD1-score3-1=4

| RD1-score3-2=4

| RD1-score3-3=

| RD1-seed4=8

| RD1-team4={{flagicon|SRB}} Laslo Đere

| RD1-score4-1=6

| RD1-score4-2=6

| RD1-score4-3=

| RD2-seed1=

| RD2-team1={{flagicon|BOL}} Hugo Dellien

| RD2-score1-1=4

| RD2-score1-2=2

| RD2-score1-3=

| RD2-seed2=8

| RD2-team2={{flagicon|SRB}} Laslo Đere

| RD2-score2-1=6

| RD2-score2-2=6

| RD2-score2-3=

}}

==Third qualifier==

{{4TeamBracket-Tennis3

| RD1=First round

| RD2=Qualifying competition

| team-width=175

| RD1-seed1=3

| RD1-team1={{flagicon|FRA}} Ugo Humbert

| RD1-score1-1=3

| RD1-score1-2=3

| RD1-score1-3=

| RD1-seed2=

| RD1-team2={{flagicon|USA}} Brandon Nakashima

| RD1-score2-1=6

| RD1-score2-2=6

| RD1-score2-3=

| RD1-seed3=

| RD1-team3={{flagicon|POL}} Kamil Majchrzak

| RD1-score3-1=6

| RD1-score3-2=6

| RD1-score3-3=

| RD1-seed4=11

| RD1-team4={{flagicon|ARG}} Federico Coria

| RD1-score4-1=4

| RD1-score4-2=2

| RD1-score4-3=

| RD2-seed1=

| RD2-team1={{flagicon|USA}} Brandon Nakashima

| RD2-score1-1=6

| RD2-score1-2=7⁷

| RD2-score1-3=

| RD2-seed2=

| RD2-team2={{flagicon|POL}} Kamil Majchrzak

| RD2-score2-1=4

| RD2-score2-2=6⁵

| RD2-score2-3=

}}

==Fourth qualifier==

{{4TeamBracket-Tennis3

| RD1=First round

| RD2=Qualifying competition

| team-width=175

| RD1-seed1=4

| RD1-team1={{flagicon|SVK}} Alex Molčan

| RD1-score1-1=7⁷

| RD1-score1-2=3

| RD1-score1-3=2

| RD1-seed2=WC

| RD1-team2={{flagicon|ITA}} Giulio Zeppieri

| RD1-score2-1=6³

| RD1-score2-2=6

| RD1-score2-3=6

| RD1-seed3=WC

| RD1-team3={{flagicon|ITA}} Francesco Forti

| RD1-score3-1=1

| RD1-score3-2=3

| RD1-score3-3=

| RD1-seed4=14

| RD1-team4={{flagicon|USA}} Maxime Cressy

| RD1-score4-1=6

| RD1-score4-2=6

| RD1-score4-3=

| RD2-seed1=WC

| RD2-team1={{flagicon|ITA}} Giulio Zeppieri

| RD2-score1-1=4

| RD2-score1-2=6

| RD2-score1-3=7⁷

| RD2-seed2=14

| RD2-team2={{flagicon|USA}} Maxime Cressy

| RD2-score2-1=6

| RD2-score2-2=4

| RD2-score2-3=6⁵

}}

==Fifth qualifier==

{{4TeamBracket-Tennis3

| RD1=First round

| RD2=Qualifying competition

| team-width=175

| RD1-seed1=5

| RD1-team1={{flagicon|ARG}} Francisco Cerúndolo

| RD1-score1-1=7⁷

| RD1-score1-2=6

| RD1-score1-3=

| RD1-seed2=

| RD1-team2={{flagicon|JPN}} Yoshihito Nishioka

| RD1-score2-1=6⁵

| RD1-score2-2=3

| RD1-score2-3=

| RD1-seed3=

| RD1-team3={{flagicon|POR}} João Sousa

| RD1-score3-1=6

| RD1-score3-2=6

| RD1-score3-3=

| RD1-seed4=9

| RD1-team4={{flagicon|USA}} Mackenzie McDonald

| RD1-score4-1=2

| RD1-score4-2=4

| RD1-score4-3=

| RD2-seed1=5

| RD2-team1={{flagicon|ARG}} Francisco Cerúndolo

| RD2-score1-1=6

| RD2-score1-2=7⁷

| RD2-score1-3=

| RD2-seed2=

| RD2-team2={{flagicon|POR}} João Sousa

| RD2-score2-1=2

| RD2-score2-2=6⁴

| RD2-score2-3=

}}

==Sixth qualifier==

{{4TeamBracket-Tennis3

| RD1=First round

| RD2=Qualifying competition

| team-width=175

| RD1-seed1=6

| RD1-team1={{flagicon|HUN}} Márton Fucsovics

| RD1-score1-1=4

| RD1-score1-2=6

| RD1-score1-3=6

| RD1-seed2=

| RD1-team2={{flagicon|USA}} Denis Kudla

| RD1-score2-1=6

| RD1-score2-2=1

| RD1-score2-3=4

| RD1-seed3=

| RD1-team3={{flagicon|SRB}} Dušan Lajović

| RD1-score3-1=6

| RD1-score3-2=7

| RD1-score3-3=

| RD1-seed4=13

| RD1-team4={{flagicon|FRA}} Benoît Paire

| RD1-score4-1=2

| RD1-score4-2=5

| RD1-score4-3=

| RD2-seed1=6

| RD2-team1={{flagicon|HUN}} Márton Fucsovics

| RD2-score1-1=0^r

| RD2-score1-2=

| RD2-score1-3=

| RD2-seed2=

| RD2-team2={{flagicon|SRB}} Dušan Lajović

| RD2-score2-1=4

| RD2-score2-2=

| RD2-score2-3=

}}

==Seventh qualifier==

{{4TeamBracket-Tennis3

| RD1=First round

| RD2=Qualifying competition

| team-width=175

| RD1-seed1=7

| RD1-team1={{flagicon|USA}} Marcos Giron

| RD1-score1-1=6⁷

| RD1-score1-2=6

| RD1-score1-3=6

| RD1-seed2=WC

| RD1-team2={{flagicon|ITA}} Gianmarco Ferrari

| RD1-score2-1=7⁹

| RD1-score2-2=3

| RD1-score2-3=2

| RD1-seed3=

| RD1-team3={{flagicon|FRA}} Adrian Mannarino

| RD1-score3-1=4

| RD1-score3-2=4

| RD1-score3-3=

| RD1-seed4=10

| RD1-team4={{flagicon|NED}} Tallon Griekspoor

| RD1-score4-1=6

| RD1-score4-2=6

| RD1-score4-3=

| RD2-seed1=7

| RD2-team1={{flagicon|USA}} Marcos Giron

| RD2-score1-1=6⁷

| RD2-score1-2=2

| RD2-score1-3=

| RD2-seed2=10

| RD2-team2={{flagicon|NED}} Tallon Griekspoor

| RD2-score2-1=7⁹

| RD2-score2-2=6

| RD2-score2-3=

}}

References

External links

[https://www.protennislive.com/posting/2022/416/qs.pdf Qualifying draw]
[https://www.protennislive.com/posting/2022/416/MDS.pdf Main draw]

Singles men

Italian Open - Singles