21S rRNA (uridine2791-2'-O)-methyltransferase

{{Short description|Class of enzymes}}

{{Infobox enzyme

| Name = 21S rRNA (uridine2791-2'-O)-methyltransferase

| EC_number = 2.1.1.168

| CAS_number =

| GO_code =

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21S rRNA (uridine²⁷⁹¹-2'-O)-methyltransferase ({{EC number|2.1.1.168}}, MRM2 (gene), mitochondrial 21S rRNA methyltransferase, mitochondrial rRNA MTase 2) is an enzyme with systematic name S-adenosyl-L-methionine:21S rRNA (uridine²⁷⁹¹-2'-O-)-methyltransferase.{{cite journal | vauthors = Pintard L, Bujnicki JM, Lapeyre B, Bonnerot C | title = MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase | journal = The EMBO Journal | volume = 21 | issue = 5 | pages = 1139–47 | date = March 2002 | pmid = 11867542 | pmc = 125888 | doi = 10.1093/emboj/21.5.1139 }} This enzyme catalyses the following chemical reaction

: S-adenosyl-L-methionine + uridine²⁷⁹1 in 21S rRNA $\backslash rightleftharpoons$ S-adenosyl-L-homocysteine + 2'-O-methyluridine²⁷⁹¹ in 21S rRNA

The enzyme catalyses the methylation of uridine²⁷⁹¹ of mitochondrial 21S rRNA.