22

• Titanium, a transition metal in the periodic table
• 22 Kalliope, an asteroid in the asteroid belt
• (22) Kalliope I Linus, a large asteroid moon orbiting 22 Kalliope

• 22 (album), a 2022 album by Craig David
• 22, a 2003 album by Parva
• "22" (Lily Allen song), 2009
• "22" (Taylor Swift song), 2013
• "22" (Sarah McTernan song), 2019 song that represented Ireland in the Eurovision Song Contest 2019
• "22", a song by Gavin James from the album Bitter Pill, 2015
• 22 (also known as "Marsha Hunt's 22"), an early 1970s British rock band fronted by Marsha Hunt
• "Twenty Two" (Millencolin song), 1997
• "Intentions (22)", a 2019 song by Ziggy Alberts

• "Twenty Two" (The Twilight Zone), a 1961 episode of The Twilight Zone
• Revista 22 or 22 Magazine, a Romanian weekly
• 22, a fictional character in the 2020 animated film Soul
• 22, main character in the cartoon series Calling Cat-22
• .22 caliber, a family of firearms and firearm cartridges
• the 22, the 1922 Committee, association of Conservative MPs in the United Kingdom parliament
• Daimler Twenty-Two, a luxury car
• Lockheed Martin F-22 Raptor, American stealth air superiority fighter jet

• 22, A Million, a 2016 album by Bon Iver
• Twenty Plus Two, a 1961 American film noir
• List of highways numbered 22

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