2C-T-8

The full name of the chemical is 2,5-dimethoxy-4-cyclopropylmethylthiophenethylamine. The compound is reported to have a bad taste and smell.{{citation needed|date=November 2012}}

In his book PiHKAL, Shulgin lists the dosage range as 30 to 50 mg.{{CitePiHKAL}} [http://www.erowid.org/library/books_online/pihkal/pihkal044.shtml 2C-T-8 Entry in PiHKAL] 2C-T-8 is generally taken orally and effects typically last 10 to 15 hours. Experiences have varied between insight and creativity at low doses to hypersensitivity and paranoia at higher doses. A "thinking-connection" that is characteristic of the 2C-T group is evident in this chemical in stark contrast to the "pure euphoria" of phenethylamines such as MDMA.

2C-T-8 is unscheduled and uncontrolled in the United States, but possession and sales of 2C-T-8 will probably be prosecuted under the Federal Analog Act because of its structural similarities to 2C-T-7. However, 2C-T-8, unlike many other phenethylamines has not been sold by internet retailers. In the wake of Operation Web Tryp in July 2004, the issue of possession and sales of 2C-T-8 and other similar chemicals will probably be resolved in the courtroom as will the fate of this rare but unique psychedelic.{{needs update|date=June 2019}}

As of October 31, 2016, 2C-T-8 is a controlled substance (Schedule III) in Canada.{{Cite web|url=http://gazette.gc.ca/rp-pr/p2/2016/2016-05-04/html/sor-dors72-eng.php|title=Canada Gazette – Regulations Amending the Food and Drug Regulations (Part J — 2C-phenethylamines)|date=4 May 2016}}

{{original research|date=September 2019}}

The mechanism that produces 2C-T-8's hallucinogenic and entheogenic effects has not been specifically established, however it is most likely to result from action as a 5-HT_2A serotonin receptor agonist in the brain, a mechanism of action shared by all of the hallucinogenic tryptamines and phenethylamines for which the mechanism of action is known.

The toxicity of 2C-T-8 is not well documented. 2C-T-8 is somewhat less potent than 2C-T-7, but it may be expected that at higher doses it would display similar toxicity to that of other phenethylamines of the 2C-T family.

There have been no confirmed deaths due to 2C-T-8,{{Citation needed|date=March 2008}} though this may in part be due to its rarity and limited usage. Of the 2C-T family, there have been a few confirmed deaths due to 2C-T-7, which involved either insufflating large (>30 mg) doses[http://www.erowid.org/chemicals/2ct7/2ct7_death1.shtml Erowid.org][http://www.erowid.org/chemicals/2ct7/2ct7_death2.shtml Erowid.org] and in one case an unknown oral dose was combined with 200 mg MDMA.[http://www.erowid.org/chemicals/2ct7/2ct7_death3.shtml Erowid.org]

2C-T-8 is unknown on the black market. Limited accounts of 2C-T-8 can be found in the book PiHKAL.

• 2C-T-33

{{Reflist}}

{{Psychedelics}}

{{Phenethylamines}}

Category:2C (psychedelics)

Category:Cyclopropyl compounds

Category:Psychedelic phenethylamines

Category:Thioethers