3-dehydroquinate synthase II

{{Short description|Class of enzymes}}

{{Infobox enzyme

| Name = 3-dehydroquinate synthase II

| EC_number = 1.4.1.24

| CAS_number =

| GO_code =

| image =

| width =

| caption =

}}

3-dehydroquinate synthase II ({{EC number|1.4.1.24}}, DHQ synthase II, MJ1249 (gene), aroB' (gene)) is an enzyme with systematic name 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate:NAD⁺ oxidoreductase (deaminating).{{cite journal | vauthors = White RH | title = L-Aspartate semialdehyde and a 6-deoxy-5-ketohexose 1-phosphate are the precursors to the aromatic amino acids in Methanocaldococcus jannaschii | journal = Biochemistry | volume = 43 | issue = 23 | pages = 7618–27 | date = June 2004 | pmid = 15182204 | doi = 10.1021/bi0495127 }} This enzyme catalyses the following chemical reaction

: 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H₂O + NAD⁺ $\backslash rightleftharpoons$ 3-dehydroquinate + NH₃ + NADH + H⁺

The enzyme was isolated from the archaeon Methanocaldococcus jannaschii.