4-hydroxyproline epimerase

{{Short description|Class of enzymes}}

{{infobox enzyme

| Name = 4-hydroxyproline epimerase

| EC_number = 5.1.1.8

| CAS_number = 9024-23-1

| GO_code = 0047580

| image =

| width =

| caption =

}}

In enzymology, a 4-hydroxyproline epimerase ({{EnzExplorer|5.1.1.8}}) is an enzyme that catalyzes the chemical reaction

:trans-4-hydroxy-L-proline $\backslash rightleftharpoons$ cis-4-hydroxy-D-proline

Hence, this enzyme has one substrate, trans-4-hydroxy-L-proline, and one product, cis-4-hydroxy-D-proline.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on amino acids and derivatives. The systematic name of this enzyme class is 4-hydroxyproline 2-epimerase. Other names in common use include hydroxyproline epimerase, hydroxyproline 2-epimerase, and L-hydroxyproline epimerase. This enzyme participates in arginine and proline metabolism.