5-Formiminotetrahydrofolate
{{chembox
| Verifiedfields = changed
| verifiedrevid = 477224528
| ImageFile=5-formiminotetrahydrofolate.png
| ImageSize=250px
| ImageAlt = Skeletal formula of 5-formiminotetrahydrofolate.
| ImageFile1 = 5-Formiminotetrahydrofolate-3D-spacefill.png
| ImageSize1 = 250
| ImageAlt1 = Skeletal formula of the 5-formiminotetrahydrofolate molecule
| IUPACName=(2S)-2-
| OtherNames=
|Section1={{Chembox Identifiers
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 21232465
| InChI = 1/C20H24N8O6/c21-9-28-12(8-24-16-15(28)18(32)27-20(22)26-16)7-23-11-3-1-10(2-4-11)17(31)25-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,21,23H,5-8H2,(H,25,31)(H,29,30)(H,33,34)(H4,22,24,26,27,32)/p-2/t12-,13+/m1/s1
| InChIKey = YCWUVLPMLLBDCU-ALWAAHSPBC
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C20H24N8O6/c21-9-28-12(8-24-16-15(28)18(32)27-20(22)26-16)7-23-11-3-1-10(2-4-11)17(31)25-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,21,23H,5-8H2,(H,25,31)(H,29,30)(H,33,34)(H4,22,24,26,27,32)/p-2
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = YCWUVLPMLLBDCU-UHFFFAOYSA-L
| CASNo_Ref = {{cascite|changed|??}}
| CASNo=2311-81-1
| PubChem=530
| SMILES = c1cc(ccc1C(=O)NC(CCC(=O)[O-])C(=O)[O-])NCC2CNc3c(c(=O)[nH]c(n3)N)N2C=N
}}
|Section2={{Chembox Properties
| Formula=C20H24N8O6
| MolarMass=472.455
| Appearance=
| Density=
| MeltingPt=
| BoilingPt=
| Solubility=
}}
|Section3={{Chembox Hazards
| MainHazards=
| FlashPt=
| AutoignitionPt =
}}
}}
5-Formiminotetrahydrofolate is an intermediate in the catabolism of histidine. It is produced by glutamate formimidoyltransferase and then converted into 5,10-methenyltetrahydrofolate by formiminotransferase cyclodeaminase.{{cite journal |author=Fowler B |title=The folate cycle and disease in humans |journal=Kidney Int. Suppl. |volume=78 |pages=S221–9 |date=February 2001 |pmid=11169015 |doi=10.1046/j.1523-1755.2001.59780221.x|doi-access=free }}
References
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{{DEFAULTSORT:Formiminotetrahydrofolate, 5-}}
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