5-HT2 receptor
{{Short description|Transmembrane protein}}
{{DISPLAYTITLE:5-HT2 receptor}}
The 5-HT2 receptors are a subfamily of 5-HT receptors that bind the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).{{cite journal | vauthors = Hoyer D, Clarke DE, Fozard JR, Hartig PR, Martin GR, Mylecharane EJ, Saxena PR, Humphrey PP | title = International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin) | journal = Pharmacol. Rev. | volume = 46 | issue = 2 | pages = 157–203 | year = 1994 | pmid = 7938165 | url = http://pharmrev.aspetjournals.org/cgi/content/abstract/46/2/157}} The 5-HT2 subfamily consists of three G protein-coupled receptors (GPCRs) which are coupled to Gq/G11 and mediate excitatory neurotransmission,{{cite journal | vauthors = Eison AS, Mullins UL | title = Regulation of central 5-HT2A receptors: a review of in vivo studies | journal = Behavioural Brain Research | volume = 73 | issue = 1–2 | pages = 177–81 | year = 1996 | pmid = 8788498 | doi = 10.1016/0166-4328(96)00092-7}} including 5-HT2A, 5-HT2B, and 5-HT2C. For more information, please see the respective main articles of the individual subtypes:
See also
References
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{{G protein-coupled receptors}}
{{Cell signaling}}
{{Serotonergics}}