60S ribosomal protein L26

Cytosolic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 rRNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the universal ribosomal protein uL24 family. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome and the human paralog RPL26L1.

RPL26 has been shown to interact with Mdm2.{{cite journal | vauthors = Ofir-Rosenfeld Y, Boggs K, Michael D, Kastan MB, Oren M | title = Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26 | journal = Mol. Cell | volume = 32 | issue = 2 | pages = 180–9 | date = Oct 2008 | pmid = 18951086 | pmc = 2587494 | doi = 10.1016/j.molcel.2008.08.031 }}

• Eukaryotic translation
• 60S ribosomal subunit

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• [https://www.ebi.ac.uk/pdbe/pdbe-kb/proteins/P61254 PDBe-KB] provides an overview of all the structure information available in the PDB for Human 60S ribosomal protein L26

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Category:Ribosomal proteins