ABCA8
{{Short description|Protein-coding gene in the species Homo sapiens}}
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ABC-type organic anion transporter ABCA8 is a protein that in humans is encoded by the ABCA8 gene.{{cite web | title = ABCA8 ATP binding cassette subfamily A member 8 [ Homo sapiens (human) ]| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10351| accessdate = }}
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. This protein is a member of the ABCA subfamily. Members of the ABCA subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes.
References
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Further reading
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- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal|doi-access=free }}
- {{cite journal | author = Mammalian Gene Collection Program Team | display-authors = 4 | last2 = Strausberg | first2 = R. L. | last3 = Feingold | first3 = E. A. | last4 = Grouse | first4 = L. H. | last5 = Derge | first5 = J. G. | last6 = Klausner | first6 = R. D. | last7 = Collins | first7 = F. S. | last8 = Wagner | first8 = L. | last9 = Shenmen | first9 = C. M. | last10 = Schuler | first10 = G. D. | doi = 10.1073/pnas.242603899 | title = Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences | journal = Proceedings of the National Academy of Sciences | volume = 99 | issue = 26 | pages = 16899–16903 | pmc = 139241 | year = 2002 | pmid = 12477932| bibcode = 2002PNAS...9916899M | doi-access = free }}
- {{cite journal |vauthors=Tsuruoka S, Ishibashi K, Yamamoto H |title=Functional analysis of ABCA8, a new drug transporter. |journal=Biochem. Biophys. Res. Commun. |volume=298 |issue= 1 |pages= 41–5 |year= 2002 |pmid= 12379217 |doi=10.1016/S0006-291X(02)02389-6 |display-authors=etal}}
- {{cite journal |vauthors=Iida A, Saito S, Sekine A |title=Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8. |journal=J. Hum. Genet. |volume=47 |issue= 6 |pages= 285–310 |year= 2002 |pmid= 12111378 |doi= 10.1007/s100380200041 |display-authors=etal|doi-access=free }}
- {{cite journal |vauthors=Harrington JJ, Sherf B, Rundlett S |title=Creation of genome-wide protein expression libraries using random activation of gene expression. |journal=Nat. Biotechnol. |volume=19 |issue= 5 |pages= 440–5 |year= 2001 |pmid= 11329013 |doi= 10.1038/88107 |s2cid=25064683 |display-authors=etal}}
- {{cite journal |vauthors=Nagase T, Ishikawa K, Suyama M |title=Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=5 |issue= 6 |pages= 355–64 |year= 1999 |pmid= 10048485 |doi=10.1093/dnares/5.6.355 |display-authors=etal|doi-access=free }}
- {{cite journal |vauthors=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=10.1101/gr.6.9.791 |doi-access=free }}
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External links
- {{UCSC genome browser|ABCA8}}
- {{UCSC gene details|ABCA8}}
{{ABC transporters}}
{{DEFAULTSORT:Abca8}}
{{gene-17-stub}}