ABI2
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{cs1 config|name-list-style=vanc}}
{{Use dmy dates|date=January 2024}}
{{Infobox_gene}}
Abl interactor 2 also known as Abelson interactor 2 (Abi-2) is a protein that in humans is encoded by the ABI2 gene.{{cite journal |vauthors=Dai Z, Pendergast AM | title = Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity | journal = Genes Dev | volume = 9 | issue = 21 | pages = 2569–82 |date=Dec 1995 | pmid = 7590236 | doi =10.1101/gad.9.21.2569 | doi-access = free }}{{cite journal |vauthors=Machado RD, Pauciulo MW, Fretwell N, Veal C, Thomson JR, Vilarino Guell C, Aldred M, Brannon CA, Trembath RC, Nichols WC | title = A physical and transcript map based upon refinement of the critical interval for PPH1, a gene for familial primary pulmonary hypertension. The International PPH Consortium | journal = Genomics | volume = 68 | issue = 2 | pages = 220–8 |date=Sep 2000 | pmid = 10964520 | doi = 10.1006/geno.2000.6291 }}{{cite web | title = Entrez Gene: ABI2 abl interactor 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10152}}
Interactions
ABI2 has been shown to interact with ABL1,{{cite journal |vauthors=Cao C, Leng Y, Li C, Kufe D | title = Functional interaction between the c-Abl and Arg protein-tyrosine kinases in the oxidative stress response | journal = J. Biol. Chem. | volume = 278 | issue = 15 | pages = 12961–7 |date=April 2003 | pmid = 12569093 | doi = 10.1074/jbc.M300058200 | doi-access = free }} ADAM19,{{cite journal |vauthors=Huang L, Feng L, Yang L, Zhou W, Zhao S, Li C | title = Screen and identification of proteins interacting with ADAM19 cytoplasmic tail | journal = Mol. Biol. Rep. | volume = 29 | issue = 3 | pages = 317–23 |date=September 2002 | pmid = 12463424 | doi = 10.1023/A:1020409217215| s2cid = 22611084 }} and TRIM32.{{cite journal |vauthors=Kano S, Miyajima N, Fukuda S, Hatakeyama S | title = Tripartite motif protein 32 facilitates cell growth and migration via degradation of Abl-interactor 2 | journal = Cancer Res. | volume = 68 | issue = 14 | pages = 5572–80 |date=July 2008 | pmid = 18632609 | doi = 10.1158/0008-5472.CAN-07-6231 | doi-access = free }}
References
{{Reflist}}
Further reading
{{Refbegin| 2}}
- {{cite journal |vauthors=Ichigotani Y, Fujii K, Hamaguchi M, Matsuda S |title=In search of a function for the E3B1/Abi2/Argbp1/NESH family (Review). |journal=Int. J. Mol. Med. |volume=9 |issue= 6 |pages= 591–5 |year= 2002 |pmid= 12011975 |doi= 10.3892/ijmm.9.6.591}}
- {{cite journal |vauthors=Wang B, Mysliwiec T, Krainc D |title=Identification of ArgBP1, an Arg protein tyrosine kinase binding protein that is the human homologue of a CNS-specific Xenopus gene. |journal=Oncogene |volume=12 |issue= 9 |pages= 1921–9 |year= 1996 |pmid= 8649853 |display-authors=etal}}
- {{cite journal |vauthors=Juang JL, Hoffmann FM |title=Drosophila abelson interacting protein (dAbi) is a positive regulator of abelson tyrosine kinase activity. |journal=Oncogene |volume=18 |issue= 37 |pages= 5138–47 |year= 1999 |pmid= 10498863 |doi= 10.1038/sj.onc.1202911 |doi-access= free }}
- {{cite journal |vauthors=Chen B, Borinstein SC, Gillis J |title=The glioma-associated protein SETA interacts with AIP1/Alix and ALG-2 and modulates apoptosis in astrocytes. |journal=J. Biol. Chem. |volume=275 |issue= 25 |pages= 19275–81 |year= 2000 |pmid= 10858458 |doi= 10.1074/jbc.M908994199 |display-authors=etal|doi-access=free }}
- {{cite journal |vauthors=Machado RD, Pauciulo MW, Fretwell N |title=A physical and transcript map based upon refinement of the critical interval for PPH1, a gene for familial primary pulmonary hypertension. The International PPH Consortium. |journal=Genomics |volume=68 |issue= 2 |pages= 220–8 |year= 2001 |pmid= 10964520 |doi= 10.1006/geno.2000.6291 |display-authors=etal}}
- {{cite journal |vauthors=Courtney KD, Grove M, Vandongen H |s2cid=7370589 |title=Localization and phosphorylation of Abl-interactor proteins, Abi-1 and Abi-2, in the developing nervous system. |journal=Mol. Cell. Neurosci. |volume=16 |issue= 3 |pages= 244–57 |year= 2000 |pmid= 10995551 |doi= 10.1006/mcne.2000.0865 |display-authors=etal}}
- {{cite journal |vauthors=Stradal T, Courtney KD, Rottner K |title=The Abl interactor proteins localize to sites of actin polymerization at the tips of lamellipodia and filopodia. |journal=Curr. Biol. |volume=11 |issue= 11 |pages= 891–5 |year= 2001 |pmid= 11516653 |doi=10.1016/S0960-9822(01)00239-1 |s2cid=1861695 |display-authors=etal|doi-access=free |bibcode=2001CBio...11..891S }}
- {{cite journal |vauthors=Huang L, Feng L, Yang L |title=Screen and identification of proteins interacting with ADAM19 cytoplasmic tail. |journal=Mol. Biol. Rep. |volume=29 |issue= 3 |pages= 317–23 |year= 2003 |pmid= 12463424 |doi=10.1023/A:1020409217215 |s2cid=22611084 |display-authors=etal}}
- {{cite journal | author = Mammalian Gene Collection Program Team | display-authors = 4 | last2 = Strausberg | first2 = R. L. | last3 = Feingold | first3 = E. A. | last4 = Grouse | first4 = L. H. | last5 = Derge | first5 = J. G. | last6 = Klausner | first6 = R. D. | last7 = Collins | first7 = F. S. | last8 = Wagner | first8 = L. | last9 = Shenmen | first9 = C. M. | last10 = Schuler | first10 = G. D. | doi = 10.1073/pnas.242603899 | title = Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences | journal = Proceedings of the National Academy of Sciences | volume = 99 | issue = 26 | pages = 16899–16903 | pmc = 139241 | year = 2002 | pmid = 12477932| bibcode = 2002PNAS...9916899M | doi-access = free }}
- {{cite journal |vauthors=Cao C, Leng Y, Li C, Kufe D |title=Functional interaction between the c-Abl and Arg protein-tyrosine kinases in the oxidative stress response |journal=J. Biol. Chem. |volume=278 |issue= 15 |pages= 12961–7 |year= 2003 |pmid= 12569093 |doi= 10.1074/jbc.M300058200 |doi-access= free }}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal|doi-access=free }}
- {{cite journal |vauthors=Brandenberger R, Wei H, Zhang S |title=Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation |journal=Nat. Biotechnol. |volume=22 |issue= 6 |pages= 707–16 |year= 2005 |pmid= 15146197 |doi= 10.1038/nbt971 |s2cid=27764390 |display-authors=etal}}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
- {{cite journal |vauthors=Eastman SW, Martin-Serrano J, Chung W |title=Identification of human VPS37C, a component of endosomal sorting complex required for transport-I important for viral budding |journal=J. Biol. Chem. |volume=280 |issue= 1 |pages= 628–36 |year= 2005 |pmid= 15509564 |doi= 10.1074/jbc.M410384200 |display-authors=etal|doi-access=free }}
- {{cite journal |vauthors=Rual JF, Venkatesan K, Hao T |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |bibcode=2005Natur.437.1173R |s2cid=4427026 |display-authors=etal}}
- {{cite journal |vauthors=Luo X, Levens E, Williams RS, Chegini N |title=The expression of Abl interactor 2 in leiomyoma and myometrium and regulation by GnRH analogue and transforming growth factor-beta |journal=Hum. Reprod. |volume=21 |issue= 6 |pages= 1380–6 |year= 2006 |pmid= 16488906 |doi= 10.1093/humrep/del011 |doi-access= free }}
- {{cite journal |vauthors=Hirao N, Sato S, Gotoh T |title=NESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylation |journal=FEBS Lett. |volume=580 |issue= 27 |pages= 6464–70 |year= 2007 |pmid= 17101133 |doi= 10.1016/j.febslet.2006.10.065 |s2cid=20005197 |display-authors=etal|doi-access=free }}
- {{cite journal |vauthors=Li Y, Clough N, Sun X |title=BCR-ABL Induces Abnormal Cytoskeleton Remodeling, β1 Integrin Clustering, and Increased Cell Adhesion to Fibronectin Through ABL Interactor 1 Pathway |journal=J. Cell Sci. |volume=120 |issue= Pt 8 |pages= 1436–46 |year= 2007 |pmid= 17389688 |doi= 10.1242/jcs.03430 | pmc=1950936 |display-authors=etal}}
{{Refend}}
External links
- {{UCSC genome browser|ABI2}}
- {{UCSC gene details|ABI2}}
{{DEFAULTSORT:Abi2}}
{{Gene-2-stub}}