ADCK2

ADCK2 is predicted to possess ATP binding activity and protein serine/threonine kinase activity. The protein is predicted to be an integral part of the membrane.{{cite web | url=https://www.ncbi.nlm.nih.gov/gene/90956 | title=ADCK2 aarF domain containing kinase 2 [Homo sapiens (Human)] - Gene – NCBI }}

The ADCK2 gene is located on chromosome 7q34. The genomic sequence spans 22,165 base pairs from 140,672,945 to 140,695,110 on the GRCh38.p14 primary assembly. It consists of 8 exons.

ADCK2 is ubiquitously expressed across various human tissues, with notable expression in skin and brain tissue, among others.

Research indicates that ADCK2 may have therapeutic implications in diseases such as myopathy.{{cite journal |last1=Vázquez-Fonseca |first1=L |last2=Schaefer |first2=J |last3=Navas-Enamorado |first3=I |last4=Santos-Ocaña |first4=C |last5=Hernández-Camacho |first5=JD |last6=Guerra |first6=I |last7=Cascajo |first7=MV |last8=Sánchez-Cuesta |first8=A |last9=Horvath |first9=Z |last10=Siendones |first10=E |last11=Jou |first11=C |last12=Casado |first12=M |last13=Gutiérrez |first13=P |last14=Brea-Calvo |first14=G |last15=López-Lluch |first15=G |last16=Fernández-Ayala |first16=DJM |last17=Cortés-Rodríguez |first17=AB |last18=Rodríguez-Aguilera |first18=JC |last19=Matté |first19=C |last20=Ribes |first20=A |last21=Prieto-Soler |first21=SY |last22=Dominguez-Del-Toro |first22=E |last23=Francesco |first23=AD |last24=Aon |first24=MA |last25=Bernier |first25=M |last26=Salviati |first26=L |last27=Artuch |first27=R |last28=Cabo |first28=R |last29=Jackson |first29=S |last30=Navas |first30=P |title=ADCK2 Haploinsufficiency Reduces Mitochondrial Lipid Oxidation and Causes Myopathy Associated with CoQ Deficiency. |journal=Journal of Clinical Medicine |date=2 September 2019 |volume=8 |issue=9 |page=1374 |doi=10.3390/jcm8091374 |doi-access=free |pmid=31480808|hdl=10261/209337 |hdl-access=free }}

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Category:EC 2.7.11

Category:Genes on human chromosome 7