ADCY3

This gene encodes adenylyl cyclase 3, which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP).

The ADCY3 subtype likely mediates odorant detection (possibly) via modulation of intracellular cAMP concentration.{{cite web | title = Gene Cards: ADCY3 Gene| url = https://www.genecards.org/cgi-bin/carddisp.pl?gene=ADCY3| access-date = 2012-12-30}}

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• {{UCSC gene info|ADCY3}}

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• {{cite journal | vauthors = Gaudin C, Homcy CJ, Ishikawa Y | title = Mammalian adenylyl cyclase family members are randomly located on different chromosomes | journal = Human Genetics | volume = 94 | issue = 5 | pages = 527–9 | date = Nov 1994 | pmid = 7959689 | doi = 10.1007/BF00211020 | s2cid = 40521157 }}
• {{cite journal | vauthors = Haber N, Stengel D, Defer N, Roeckel N, Mattei MG, Hanoune J | title = Chromosomal mapping of human adenylyl cyclase genes type III, type V and type VI | journal = Human Genetics | volume = 94 | issue = 1 | pages = 69–73 | date = Jul 1994 | pmid = 8034296 | doi = 10.1007/BF02272844 | s2cid = 6473135 }}
• {{cite journal | vauthors = Hellevuo K, Yoshimura M, Kao M, Hoffman PL, Cooper DM, Tabakoff B | title = A novel adenylyl cyclase sequence cloned from the human erythroleukemia cell line | journal = Biochemical and Biophysical Research Communications | volume = 192 | issue = 1 | pages = 311–318 | date = Apr 1993 | pmid = 8476432 | doi = 10.1006/bbrc.1993.1415 }}
• {{cite journal | vauthors = Wei J, Wayman G, Storm DR | title = Phosphorylation and inhibition of type III adenylyl cyclase by calmodulin-dependent protein kinase II in vivo | journal = The Journal of Biological Chemistry | volume = 271 | issue = 39 | pages = 24231–24235 | date = Sep 1996 | pmid = 8798667 | doi = 10.1074/jbc.271.39.24231 | doi-access = free }}
• {{cite journal | vauthors = Nagase T, Ishikawa K, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O | title = Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro | journal = DNA Research | volume = 5 | issue = 1 | pages = 31–39 | date = Feb 1998 | pmid = 9628581 | doi = 10.1093/dnares/5.1.31 | doi-access = free }}
• {{cite journal | vauthors = Wei J, Zhao AZ, Chan GC, Baker LP, Impey S, Beavo JA, Storm DR | title = Phosphorylation and inhibition of olfactory adenylyl cyclase by CaM kinase II in Neurons: a mechanism for attenuation of olfactory signals | journal = Neuron | volume = 21 | issue = 3 | pages = 495–504 | date = Sep 1998 | pmid = 9768837 | doi = 10.1016/S0896-6273(00)80561-9 | s2cid = 9860137 | doi-access = free }}
• {{cite journal | vauthors = Barcova M, Speth C, Kacani L, Uberall F, Stoiber H, Dierich MP | title = Involvement of adenylate cyclase and p70(S6)-kinase activation in IL-10 up-regulation in human monocytes by gp41 envelope protein of human immunodeficiency virus type 1 | journal = Pflügers Archiv | volume = 437 | issue = 4 | pages = 538–546 | date = Mar 1999 | pmid = 10089566 | doi = 10.1007/s004240050815 | s2cid = 7620262 }}
• {{cite journal | vauthors = Speth C, Joebstl B, Barcova M, Dierich MP | title = HIV-1 envelope protein gp41 modulates expression of interleukin-10 and chemokine receptors on monocytes, astrocytes and neurones | journal = AIDS | volume = 14 | issue = 6 | pages = 629–636 | date = Apr 2000 | pmid = 10807185 | doi = 10.1097/00002030-200004140-00001 | s2cid = 22105709 | doi-access = free }}
• {{cite journal | vauthors = Patke CL, Shearer WT | title = gp120- and TNF-alpha-induced modulation of human B cell function: proliferation, cyclic AMP generation, Ig production, and B-cell receptor expression | journal = The Journal of Allergy and Clinical Immunology | volume = 105 | issue = 5 | pages = 975–982 | date = May 2000 | pmid = 10808179 | doi = 10.1067/mai.2000.105315 | doi-access = free }}
• {{cite journal | vauthors = Vanvooren V, Allgeier A, Cosson E, Van Sande J, Defer N, Pirlot M, Hanoune J, Dumont JE | title = Expression of multiple adenylyl cyclase isoforms in human and dog thyroid | journal = Molecular and Cellular Endocrinology | volume = 170 | issue = 1–2 | pages = 185–196 | date = Dec 2000 | pmid = 11162902 | doi = 10.1016/S0303-7207(00)00322-1 | s2cid = 20099267 }}
• {{cite journal | vauthors = Patrizio M, Colucci M, Levi G | title = Human immunodeficiency virus type 1 Tat protein decreases cyclic AMP synthesis in rat microglia cultures | journal = Journal of Neurochemistry | volume = 77 | issue = 2 | pages = 399–407 | date = Apr 2001 | pmid = 11299302 | doi = 10.1046/j.1471-4159.2001.00249.x | s2cid = 24053412 | doi-access = free }}
• {{cite journal | vauthors = Côté M, Guillon G, Payet MD, Gallo-Payet N | title = Expression and regulation of adenylyl cyclase isoforms in the human adrenal gland | journal = The Journal of Clinical Endocrinology and Metabolism | volume = 86 | issue = 9 | pages = 4495–4503 | date = Sep 2001 | doi = 10.1210/jcem.86.9.7837 | pmid = 11549699 | doi-access = free }}
• {{cite journal | vauthors = Speth C, Schabetsberger T, Mohsenipour I, Stöckl G, Würzner R, Stoiber H, Lass-Flörl C, Dierich MP | title = Mechanism of human immunodeficiency virus-induced complement expression in astrocytes and neurons | journal = Journal of Virology | volume = 76 | issue = 7 | pages = 3179–3188 | date = Apr 2002 | pmid = 11884542 | pmc = 136041 | doi = 10.1128/JVI.76.7.3179-3188.2002 }}
• {{cite journal | vauthors = Kobayakawa K, Hayashi R, Morita K, Miyamichi K, Oka Y, Tsuboi A, Sakano H | title = Stomatin-related olfactory protein, SRO, specifically expressed in the murine olfactory sensory neurons | journal = The Journal of Neuroscience | volume = 22 | issue = 14 | pages = 5931–7 | date = Jul 2002 | pmid = 12122055 | doi = 10.1523/JNEUROSCI.22-14-05931.2002| pmc = 6757947 }}
• {{cite journal | vauthors = Ludwig MG, Seuwen K | title = Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms | journal = Journal of Receptor and Signal Transduction Research | volume = 22 | issue = 1–4 | pages = 79–110 | year = 2003 | pmid = 12503609 | doi = 10.1081/RRS-120014589 | s2cid = 36697419 }}
• {{cite journal | vauthors = Katsel PL, Tagliente TM, Schwarz TE, Craddock-Royal BD, Patel ND, Maayani S | title = Molecular and biochemical evidence for the presence of type III adenylyl cyclase in human platelets | journal = Platelets | volume = 14 | issue = 1 | pages = 21–33 | date = Feb 2003 | pmid = 12623444 | doi = 10.1080/0953710021000062905 | s2cid = 7194996 | url = https://zenodo.org/record/896544 }}
• {{cite journal | vauthors = Celano M, Arturi F, Presta I, Bruno R, Scarpelli D, Calvagno MG, Cristofaro C, Bulotta S, Giannasio P, Sacco R, Filetti S, Russo D | title = Expression of adenylyl cyclase types III and VI in human hyperfunctioning thyroid nodules | journal = Molecular and Cellular Endocrinology | volume = 203 | issue = 1–2 | pages = 129–135 | date = May 2003 | pmid = 12782409 | doi = 10.1016/S0303-7207(03)00086-8 | s2cid = 24573371 }}

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Category:EC 4.6.1

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