ADCY7

This gene encodes a membrane-bound adenylyl cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium. The product of this gene is a member of the adenylyl cyclase class-4/guanylyl cyclase enzyme family that is characterized by the presence of twelve membrane-spanning domains in its sequences.

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• {{UCSC gene info|ADCY7}}

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• {{cite journal | vauthors=Nomura N, Miyajima N, Sazuka T |title=Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 |journal=DNA Res. |volume=1 |issue= 1 |pages= 27–35 |year= 1995 |pmid= 7584026 |doi=10.1093/dnares/1.1.27 |display-authors=etal|doi-access=free }}
• {{cite journal | vauthors=Nomura N, Miyajima N, Sazuka T |title=Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement) |journal=DNA Res. |volume=1 |issue= 1 |pages= 47–56 |year= 1995 |pmid= 7584028 |doi=10.1093/dnares/1.1.47 |display-authors=etal|doi-access=free }}
• {{cite journal | vauthors=Hellevuo K, Welborn R, Menninger JA, Tabakoff B |title=Human adenylyl cyclase type 7 contains polymorphic repeats in the 3' untranslated region: investigations of association with alcoholism |journal=Am. J. Med. Genet. |volume=74 |issue= 1 |pages= 95–8 |year= 1997 |pmid= 9034014 |doi=10.1002/(SICI)1096-8628(19970221)74:1<95::AID-AJMG19>3.0.CO;2-M }}
• {{cite journal | vauthors=Barcova M, Speth C, Kacani L |title=Involvement of adenylate cyclase and p70(S6)-kinase activation in IL-10 up-regulation in human monocytes by gp41 envelope protein of human immunodeficiency virus type 1 |journal=Pflügers Arch. |volume=437 |issue= 4 |pages= 538–46 |year= 1999 |pmid= 10089566 |doi=10.1007/s004240050815 |s2cid=7620262 |display-authors=etal}}
• {{cite journal | vauthors=Speth C, Joebstl B, Barcova M, Dierich MP |title=HIV-1 envelope protein gp41 modulates expression of interleukin-10 and chemokine receptors on monocytes, astrocytes and neurones |journal=AIDS |volume=14 |issue= 6 |pages= 629–36 |year= 2000 |pmid= 10807185 |doi=10.1097/00002030-200004140-00001 |s2cid=22105709 |doi-access=free }}
• {{cite journal | vauthors=Patke CL, Shearer WT |title=gp120- and TNF-alpha-induced modulation of human B cell function: proliferation, cyclic AMP generation, Ig production, and B-cell receptor expression |journal=J. Allergy Clin. Immunol. |volume=105 |issue= 5 |pages= 975–82 |year= 2000 |pmid= 10808179 |doi= 10.1067/mai.2000.105315 |doi-access= free }}
• {{cite journal | vauthors=Patrizio M, Colucci M, Levi G |title=Human immunodeficiency virus type 1 Tat protein decreases cyclic AMP synthesis in rat microglia cultures |journal=J. Neurochem. |volume=77 |issue= 2 |pages= 399–407 |year= 2001 |pmid= 11299302 |doi=10.1046/j.1471-4159.2001.00249.x |s2cid=24053412 |doi-access=free }}
• {{cite book | vauthors=Yan SZ, Tang WJ |chapter=Construction of Soluble Adenylyl Cyclase from Human Membrane-Bound Type 7 Adenylyl Cyclase |title=G Protein Pathways - Part C, Effector Mechanisms |volume=345 |pages= 231–41 |year= 2002 |pmid= 11665607 |doi=10.1016/S0076-6879(02)45019-7 | series=Methods in Enzymology | isbn=978-0-12-182246-0 }}
• {{cite journal | vauthors=Speth C, Schabetsberger T, Mohsenipour I |title=Mechanism of Human Immunodeficiency Virus-Induced Complement Expression in Astrocytes and Neurons |journal=J. Virol. |volume=76 |issue= 7 |pages= 3179–88 |year= 2002 |pmid= 11884542 |doi=10.1128/JVI.76.7.3179-3188.2002 | pmc=136041 |display-authors=etal}}
• {{cite journal | vauthors=Nelson EJ, Hellevuo K, Yoshimura M, Tabakoff B |title=Ethanol-induced phosphorylation and potentiation of the activity of type 7 adenylyl cyclase. Involvement of protein kinase C delta |journal=J. Biol. Chem. |volume=278 |issue= 7 |pages= 4552–60 |year= 2003 |pmid= 12454008 |doi= 10.1074/jbc.M210386200 |doi-access= free }}
• {{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |display-authors=etal|doi-access=free }}
• {{cite journal | vauthors=Ludwig MG, Seuwen K |title=Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms |journal=J. Recept. Signal Transduct. Res. |volume=22 |issue= 1–4 |pages= 79–110 |year= 2003 |pmid= 12503609 |doi=10.1081/RRS-120014589 |s2cid=36697419 }}
• {{cite journal | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal|doi-access=free }}
• {{cite journal | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
• {{cite journal | vauthors=Beeler JA, Yan SZ, Bykov S |title=A soluble C1b protein and its regulation of soluble type 7 adenylyl cyclase |journal=Biochemistry |volume=43 |issue= 49 |pages= 15463–71 |year= 2005 |pmid= 15581358 |doi= 10.1021/bi049088+|display-authors=etal|citeseerx=10.1.1.558.7519 }}
• {{cite journal | vauthors=Kimura K, Wakamatsu A, Suzuki Y |title=Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129 |display-authors=etal}}
• {{cite journal | vauthors=Hines LM, Hoffman PL, Bhave S |title=A sex-specific role of type VII adenylyl cyclase in depression |journal=J. Neurosci. |volume=26 |issue= 48 |pages= 12609–19 |year= 2006 |pmid= 17135423 |doi= 10.1523/JNEUROSCI.1040-06.2006 |pmc=6674903 |display-authors=etal|doi-access=free }}

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Category:EC 4.6.1

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