AD 500

• Emperor Anastasius I concludes treaties with a number of nomad tribes in northern Arabia. In return for tribute to the Byzantine Empire and military defense of these eastern territories, such tribes are permitted to settle and farm agricultural lands in Arabia (approximate date).

;Britannia

• Possible date for the Battle of Mons Badonicus: Romano-British and Celts defeat an Anglo-Saxon army, that may have been led by the bretwalda Aelle of Sussex or possibly Cerdic of Wessex (approximate date; suggested dates range from 490 to 517). This battle may have influenced the legend of King Arthur.
• Possible date at which Fergus Mór begins his reign – the historicity of Mór is doubtful.
• Approximate beginning of the Heptarchy period in the history of England.
• Approximate year of the founding of the Kingdom of Essex.
• Approximate year of the invention of the bee skep in Ireland.

• Burgundian Civil War: Battle of Dijon: A coalition of Franks and Burgundians crush the forces under Gundobad. King Clovis I pursues him to Avignon, where he surrenders and promises to pay a yearly tribute.Gregory of Tours, History, 2.32
• The Frankish Kingdom is formed (approximate date).
• The monument of Ale's Stones is built in Sweden (approximate date).
• Roman catacomb burials end (approximate date).

• Thrasamund, king of the Vandals, marries Amalafrida (widowed sister of Theodoric the Great). She brings with her a large dowry and an elite Gothic force of 5,000 soldiers.Peter Heather, The Goths (Oxford: Blackwell, 1996), p. 231
• Traders from southern Arabia settle in northern Ethiopia.

• Jijeung becomes king of the Korean kingdom of Silla.{{cite web |title=List of Rulers of Korea |url=https://www.metmuseum.org/toah/hd/koru/hd_koru.htm |website=www.metmuseum.org |access-date=21 April 2019}}

• Tikal is founded (approximate date).
• Uxmal is founded (approximate date).

North America

• First large pit house villages at Chaco Canyon are founded (approximate date).

• The Arian Baptistry is erected by Theodoric the Great, at the same time as the Basilica of Sant' Apollinare Nuovo (Ravenna).
• The Codex Argenteus, Gothic manuscript of bishop Ulfilas's translation of the Bible, is written (approximate date).

• Kaleb of Axum, Aksumite king responsible for the destruction of Himyar
• Antalas, Berber tribal leader (approximate date)
• Aregund, queen of the Franks (approximate date)
• Belisarius, Byzantine general (approximate date)
• Bhavyaviveka, Indian Madhyamaka scholar (approximate date)
• Clotilde, daughter of Clovis I (approximate date)
• David, Welsh bishop (approximate date)
• Erzhu Shilong, high-official of Northern Wei (d. 532)
• Gildas, British cleric (approximate date)
• Marcouf, missionary and saint (approximate date)
• Nonnosus, abbot and saint (approximate date)
• Octa, king of Kent (approximate date)
• Procopius, Byzantine historian (approximate date)
• Paul the Black, Syriac Orthodox Patriarch of Antioch (approximate date){{cite book | last1 =Markschies| first=Christoph|date=2011|chapter=Paul Melanos|title=Religion Past and Present|publisher=Brill|editor1=Hans Dieter Betz|editor2=Don S. Browning|editor3=Bernd Janowski|editor4=Eberhard Jüngel}}
• Theodora, Byzantine Empress (approximate date)
• Theudebert I, king of Austrasia (or 495)
• Tribonian, Byzantine jurist (approximate date)
• Xie He, Chinese writer and art historian (approximate date)

• March 29 – Gwynllyw, Welsh king and religious figure{{cite book |last1=Hemmings |first1=Andrew |title=Secret Newport |date=15 August 2017 |publisher=Amberley Publishing Limited |isbn=978-1-4456-6327-2 |page=39 |url=https://books.google.com/books?id=HfowDwAAQBAJ&pg=PT39 |language=en}}
• Dauí Tenga Uma, king of Connacht (Ireland)
• Zu Chongzhi, Chinese mathematician (b. 429)

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