AFS

• Andrew File System, a distributed networked file system
• OpenAFS, an open source implementation of the Andrew File System
• Apple File Service, implementing the Apple Filing Protocol
• Apple File System, Apple's proprietary file system
• AtheOS File System, part of the Syllable operating system

• AFS Intercultural Programs, formerly American Field Service
• Abington Friends School, in Jenkintown, Pennsylvania, United States

• Army Fire Service, UK
• Air force station
• A US Navy hull classification symbol: Combat Stores Ship (AFS)

• Alternative for Sweden, a political party in Sweden
• American Folklore Society
• American Foundry Society
• {{lang|de|Arbeitsstelle für Standardisierung}} (AfS), a workgroup of the German National Library (DNB)
• Association of Football Statisticians, UK
• Australian Flag Society
• Auxiliary Fire Service, UK and Ireland

• Afs, Idlib, a Syrian village
• Ashford railway station (Surrey) (station code:AFS), Middlesex, UK
• South Africa, ITU country code

• Advanced front-lighting system (AFS) or Adaptative Front-lighting System, for automotive headlamps
• Aeronautical fixed service, for air navigation
• Afghan afghani, unit of currency
• Afro-Seminole Creole language (ISO 639-3: oafs)
• AFS Trinity, a US company
• Allergic fungal sinusitis
• Alternative financial service
• American Foursquare, a style of house
• Atomic fluorescence spectroscopy
• Available for sale, an accounting term
• International Convention on the Control of Harmful Anti-fouling Systems on Ships, 2001
• "AFS", a song by Natanael Cano from Nata Montana, 2023
• Nikon AF-S, a type of Nikon F-mount lens

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