ALDH16A1

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

Aldehyde dehydrogenase 16 family, member A1 also known as ALDH16A1 is an aldehyde dehydrogenase gene.

Clinical significance

Mutations in the SPG21 (ACP33/maspardin) gene are associated with the mast syndrome, a type of spastic paraplegia. The protein encoded by the SPG21 gene has been shown to interact with the ALDH16A1 enzyme.{{cite journal | vauthors = Hanna MC, Blackstone C | title = Interaction of the SPG21 protein ACP33/maspardin with the aldehyde dehydrogenase ALDH16A1 | journal = Neurogenetics | volume = 10| issue = 3| pages = 217–28|date=January 2009 | pmid = 19184135 | doi = 10.1007/s10048-009-0172-6 | pmc = 5585778 }}

References

{{Reflist}}

Further reading

{{refbegin | 2}}

  • {{cite journal |vauthors =Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal|doi-access=free }}
  • {{cite journal |vauthors =Yu W, Andersson B, Worley KC |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi= 10.1101/gr.7.4.353|pmc=139146 |display-authors=etal}}
  • {{cite journal |vauthors =Andersson B, Wentland MA, Ricafrente JY |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 |display-authors=etal}}
  • {{cite journal |vauthors =Kimura K, Wakamatsu A, Suzuki Y |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 |pmc=1356129 |display-authors=etal}}
  • {{cite journal |vauthors =Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2002 |pmid= 12477932 |doi= 10.1073/pnas.242603899 |pmc=139241 |bibcode=2002PNAS...9916899M |display-authors=etal|doi-access=free }}
  • {{cite journal |vauthors =Sowa ME, Bennett EJ, Gygi SP, Harper JW |title=Defining the human deubiquitinating enzyme interaction landscape. |journal=Cell |volume=138 |issue= 2 |pages= 389–403 |year= 2009 |pmid= 19615732 |doi= 10.1016/j.cell.2009.04.042 |pmc=2716422 }}
  • {{cite journal |vauthors =Ewing RM, Chu P, Elisma F |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= 1|pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 |pmc=1847948 |display-authors=etal}}

{{refend}}

{{Aldehyde dehydrogenases}}

{{gene-19-stub}}