ALDH1L2

{{Short description|Protein-coding gene in humans}}

{{Infobox_gene}}

Aldehyde dehydrogenase 1 family, member L2 also known as ALDH1L2 is an enzyme that in humans is encoded by the ALDH1L2 gene.{{cite journal | vauthors = Strausberg RL, Feingold EA, Grouse LH | title = Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 99 | issue = 26 | pages = 16899–903 |date=December 2002 | pmid = 12477932 | pmc = 139241 | doi = 10.1073/pnas.242603899 | bibcode = 2002PNAS...9916899M |display-authors=etal| doi-access = free }}{{cite journal | vauthors = Ota T, Suzuki Y, Nishikawa T | title = Complete sequencing and characterization of 21,243 full-length human cDNAs | journal = Nat. Genet. | volume = 36 | issue = 1 | pages = 40–5 |date=January 2004 | pmid = 14702039 | doi = 10.1038/ng1285 |display-authors=etal| doi-access = free }} ALDH1L2 is the mitochondrial isoform of a similar enzyme, ALDH1L1, which converts 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide.Krupenko NI, Dubard ME, Strickland KC, Moxley KM, Oleinik NV, Krupenko SA. "[https://www.ncbi.nlm.nih.gov/pubmed/20498374 ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase.]" J Biol Chem. 2010 Jul 23;285(30):23056-63.Strickland KC, Krupenko NI, Dubard ME, Hu CJ, Tsybovsky Y, Krupenko SA. "[https://www.ncbi.nlm.nih.gov/pubmed/21238436 Enzymatic properties of ALDH1L2, a mitochondrial 10-formyltetrahdyrofolate dehydrogenase.]" Chem Biol Interact. 2011 May 30;191(1-3):129-36.