AS3MT
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Arsenite methyltransferase is an enzyme that in humans is encoded by the AS3MT gene.{{cite journal | vauthors = Lin S, Shi Q, Nix FB, Styblo M, Beck MA, Herbin-Davis KM, Hall LL, Simeonsson JB, Thomas DJ | title = A novel S-adenosyl-L-methionine:arsenic(III) methyltransferase from rat liver cytosol | journal = The Journal of Biological Chemistry | volume = 277 | issue = 13 | pages = 10795–803 | date = March 2002 | pmid = 11790780 | doi = 10.1074/jbc.M110246200 | doi-access = free }}{{cite web | title = Entrez Gene: AS3MT arsenic (+3 oxidation state) methyltransferase| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57412}}
References
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Further reading
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- {{cite journal | vauthors = Dheeman DS, Packianathan C, Pillai JK, Rosen BP | title = Pathway of human AS3MT arsenic methylation | journal = Chemical Research in Toxicology | volume = 27 | issue = 11 | pages = 1979–89 | date = November 2014 | pmid = 25325836 | pmc = 4237493 | doi = 10.1021/tx500313k }}
- {{cite journal | vauthors = Hernández A, Xamena N, Sekaran C, Tokunaga H, Sampayo-Reyes A, Quinteros D, Creus A, Marcos R | title = High arsenic metabolic efficiency in AS3MT287Thr allele carriers | journal = Pharmacogenetics and Genomics | volume = 18 | issue = 4 | pages = 349–55 | date = April 2008 | pmid = 18334919 | doi = 10.1097/FPC.0b013e3282f7f46b | s2cid = 25842224 }}
- {{cite journal | vauthors = Fujihara J, Kunito T, Agusa T, Yasuda T, Iida R, Fujii Y, Takeshita H | title = Population differences in the human arsenic (+3 oxidation state) methyltransferase (AS3MT) gene polymorphism detected by using genotyping method | journal = Toxicology and Applied Pharmacology | volume = 225 | issue = 3 | pages = 251–4 | date = December 2007 | pmid = 17889916 | doi = 10.1016/j.taap.2007.08.010 }}
- {{cite journal | vauthors = Hernández A, Xamena N, Surrallés J, Sekaran C, Tokunaga H, Quinteros D, Creus A, Marcos R | title = Role of the Met(287)Thr polymorphism in the AS3MT gene on the metabolic arsenic profile | journal = Mutation Research | volume = 637 | issue = 1–2 | pages = 80–92 | date = January 2008 | pmid = 17850829 | doi = 10.1016/j.mrfmmm.2007.07.004 }}
- {{cite journal | vauthors = Lindberg AL, Kumar R, Goessler W, Thirumaran R, Gurzau E, Koppova K, Rudnai P, Leonardi G, Fletcher T, Vahter M | title = Metabolism of low-dose inorganic arsenic in a central European population: influence of sex and genetic polymorphisms | journal = Environmental Health Perspectives | volume = 115 | issue = 7 | pages = 1081–6 | date = July 2007 | pmid = 17637926 | pmc = 1913583 | doi = 10.1289/ehp.10026 }}
- {{cite journal | vauthors = Schläwicke Engström K, Broberg K, Concha G, Nermell B, Warholm M, Vahter M | title = Genetic polymorphisms influencing arsenic metabolism: evidence from Argentina | journal = Environmental Health Perspectives | volume = 115 | issue = 4 | pages = 599–605 | date = April 2007 | pmid = 17450230 | pmc = 1852682 | doi = 10.1289/ehp.9734 }}
- {{cite journal | vauthors = Meza M, Gandolfi AJ, Klimecki WT | title = Developmental and genetic modulation of arsenic biotransformation: a gene by environment interaction? | journal = Toxicology and Applied Pharmacology | volume = 222 | issue = 3 | pages = 381–7 | date = August 2007 | pmid = 17306849 | pmc = 2040165 | doi = 10.1016/j.taap.2006.12.018 }}
- {{cite journal | vauthors = Wood TC, Salavagionne OE, Mukherjee B, Wang L, Klumpp AF, Thomae BA, Eckloff BW, Schaid DJ, Wieben ED, Weinshilboum RM | title = Human arsenic methyltransferase (AS3MT) pharmacogenetics: gene resequencing and functional genomics studies | journal = The Journal of Biological Chemistry | volume = 281 | issue = 11 | pages = 7364–73 | date = March 2006 | pmid = 16407288 | doi = 10.1074/jbc.M512227200 | doi-access = free }}
- {{cite journal | vauthors = Meza MM, Yu L, Rodriguez YY, Guild M, Thompson D, Gandolfi AJ, Klimecki WT | title = Developmentally restricted genetic determinants of human arsenic metabolism: association between urinary methylated arsenic and CYT19 polymorphisms in children | journal = Environmental Health Perspectives | volume = 113 | issue = 6 | pages = 775–81 | date = June 2005 | pmid = 15929903 | pmc = 1257606 | doi = 10.1289/ehp.7780 }}
- {{cite journal | vauthors = Li J, Waters SB, Drobna Z, Devesa V, Styblo M, Thomas DJ | title = Arsenic (+3 oxidation state) methyltransferase and the inorganic arsenic methylation phenotype | journal = Toxicology and Applied Pharmacology | volume = 204 | issue = 2 | pages = 164–9 | date = April 2005 | pmid = 15808521 | doi = 10.1016/j.taap.2004.12.002 | url = https://zenodo.org/record/1259375 }}
- {{cite journal | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1–2 | pages = 149–56 | date = October 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}
- {{cite journal | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides | journal = Gene | volume = 138 | issue = 1–2 | pages = 171–4 | date = January 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}
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External links
- {{UCSC gene info|AS3MT}}
{{One carbon transferases}}
{{Enzymes}}
{{Portal bar|Biology|border=no}}
{{enzyme-stub}}