Acetone thiosemicarbazone
{{Short description|Chemical compound}}
{{Chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 477239379
| ImageFile =Acetone thiosemicarbazone.png
| ImageSize =180px
| PIN = 2-(Propan-2-ylidene)hydrazine-1-carbothioamide
| OtherNames = (Propan-2-ylideneamino)thiourea
Acetone thiosemicarbazide
Dimethyl ketone thiosemicarbazone
Thiosemicarbazone acetone
NSC 711
2-(1-Methylethylidene)hydrazinecarbothioamide
|Section1={{Chembox Identifiers
| Abbreviations = ATSC
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 2050659
| InChI = 1/C4H9N3S/c1-3(2)6-7-4(5)8/h1-2H3,(H3,5,7,8)
| InChIKey = FQUDPIIGGVBZEQ-UHFFFAOYAR
| SMILES1 = S=C(N)N/N=C(\C)C
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 500557
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C4H9N3S/c1-3(2)6-7-4(5)8/h1-2H3,(H3,5,7,8)
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = FQUDPIIGGVBZEQ-UHFFFAOYSA-N
| CASNo_Ref = {{cascite|correct|CAS}}
| CASNo =1752-30-3
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = C3U604L47F
| PubChem =2770166
| SMILES =CC(=NNC(=S)N)C
| EINECS = 217-137-9
}}
|Section2={{Chembox Properties
| C=4 | H=9 | N=3 | S=1
| Appearance =White crystals
| Density =
| MeltingPtC = 172 to 175
| MeltingPt_notes =
| BoilingPt =
| Solubility =
}}
|Section3={{Chembox Hazards
| ExternalSDS =[http://www.tcichemicals.com/eshop/en/ns/catalog/detail/msds/en/A0059/ MSDS]
| MainHazards =Toxic
| FlashPt =
| NFPA-H = 4
| NFPA-F =
| NFPA-R =
| AutoignitionPt =
| GHSPictograms = {{GHS06}}{{GHS07}}
| GHSSignalWord = Danger
| HPhrases = {{H-phrases|300|312|330}}
| PPhrases = {{P-phrases|260|264|270|271|280|284|301+310|302+352|304+340|310|312|320|321|322|330|363|403+233|405|501}}
}}
}}
Acetone thiosemicarbazone is a chemical compound with the molecular formula C4H9N3S. It is used in the plastics industry in the manufacture of polyvinyl chloride (PVC) to terminate the polymerization process.{{US patent reference | number = 3637632 | y = 1972 | m = Jan | d = 25 | inventor = Traynor, Lee | title = Agents for shortstopping free radical polymerization of vinylidene monomers}}[http://www.88chem.com/product-Other-Chemicals/23356/Acetone-thiosemicarbazone-ATSC-.html Acetone thiosemicarbazone (ATSC)] {{webarchive |url=https://web.archive.org/web/20120227155656/http://www.88chem.com/product-Other-Chemicals/23356/Acetone-thiosemicarbazone-ATSC-.html |date=February 27, 2012 }}, 88chem.com
Toxicity
Acetone thiosemicarbazone is classified as an extremely hazardous substance in the United States as defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act (42 U.S.C. 11002), and is subject to strict reporting requirements by facilities which produce, store, or use it in significant quantities.{{Cite web | publisher = Government Printing Office | title = 40 C.F.R.: Appendix A to Part 355—The List of Extremely Hazardous Substances and Their Threshold Planning Quantities | url = http://edocket.access.gpo.gov/cfr_2008/julqtr/pdf/40cfr355AppA.pdf | edition = July 1, 2008 | access-date = October 29, 2011 | archive-url = https://web.archive.org/web/20120225051612/http://edocket.access.gpo.gov/cfr_2008/julqtr/pdf/40cfr355AppA.pdf | archive-date = February 25, 2012 | url-status = dead }}
=Symptoms of exposure=
Symptoms of acute exposure to acetone thiosemicarbazide may include nausea, vomiting, eye and skin irritation, excessive salivation, pulmonary edema, hyperglycemia, and seizures.{{Cite web|url=https://cameochemicals.noaa.gov/chemical/10000|title = ACETONE THIOSEMICARBAZIDE | CAMEO Chemicals | NOAA}}