Adenosine-tetraphosphatase

{{Short description|Class of enzymes}}

{{infobox enzyme

| Name = adenosine-tetraphosphatase

| EC_number = 3.6.1.14

| CAS_number = 37289-26-2

| GO_code = 0047624

| image =

| width =

| caption =

}}

In enzymology, an adenosine-tetraphosphatase ({{EC number|3.6.1.14}}) is an enzyme that catalyzes the chemical reaction

:adenosine 5'-tetraphosphate + H2O \rightleftharpoons ATP + phosphate

Thus, the two substrates of this enzyme are adenosine 5'-tetraphosphate and H2O, whereas its two products are ATP and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is adenosine-tetraphosphate phosphohydrolase. This enzyme participates in purine metabolism.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code {{PDB link|2V7Q}}.

References

{{reflist|1}}

  • {{cite journal |vauthors=Small GD, Cooper C | date = 1966 | title = Purification and properties of nucleoside tetraphosphate hydrolase from rabbit muscle | journal = Biochemistry | volume = 5 | pages = 14–26 | pmid = 4287215 | doi = 10.1021/bi00865a003 | issue = 1 }}

{{Acid anhydride hydrolases}}

{{Enzymes}}

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Category:EC 3.6.1

Category:Enzymes of known structure

{{3.6-enzyme-stub}}