Adrian Hayday
{{Short description|British immunologist (born 1956)}}
{{EngvarB|date=August 2017}}
{{Use dmy dates|date=August 2017}}
{{Infobox scientist
| name = Adrian Hayday
| honorific_suffix = {{post-nominals|country=GBR|size=100%|FRS|FMedSci}}
| image = Professor Adrian Hayday FMedSci FRS (cropped).jpg
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| caption = Hayday in 2016
| birth_date = {{Birth year and age|1956|04}}
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| thesis_title = Structure and activity of integrated polyoma viral DNA in transformed rat cells
| thesis_url = http://catalogue.ulrls.lon.ac.uk/record=b1525087
| thesis_year = 1979
| doctoral_advisor =
| academic_advisors = {{Plainlist|
- Susumu Tonegawa
- Mike Fried{{citation needed|date=May 2016}}}}
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| website = {{Plainlist|
- {{URL|crick.ac.uk/research/a-z-researchers/researchers-d-h/adrian-hayday/}}
- {{URL|http://www.kcl.ac.uk/lsm/research/divisions/diiid/departments/immunobiology/research/hayday}}
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}}Adrian Clive Hayday (born April 1956){{cite web|archiveurl=https://web.archive.org/web/20160728112947/https://beta.companieshouse.gov.uk/officers/4jKSvSNZvtf9Hvdh8EdtPrlnyTc/appointments |archivedate=2016-07-28 |url=https://beta.companieshouse.gov.uk/officers/4jKSvSNZvtf9Hvdh8EdtPrlnyTc/appointments |publisher=companieshouse.gov.uk |title=Adrian Clive HAYDAY |location=London |year=2016 |author=Anon |url-status=dead }} is a British immunologist who is the Kay Glendinning professor and chair in the Department of Immunobiology at King's College London and group leader at the Francis Crick Institute in the UK.{{cite web|archiveurl=https://web.archive.org/web/20150405110757/http://crick.ac.uk/research/a-z-researchers/researchers-d-h/adrian-hayday/|archivedate=2015-04-05|url=http://crick.ac.uk/research/a-z-researchers/researchers-d-h/adrian-hayday/|title=Adrian Hayday: Immunosurveillance Laboratory|publisher=crick.ac.uk|location=London|author=Anon|work=The Francis Crick Institute |year=2016}}{{cite journal|last1=Gibbons|first1=Deena|last2=Fleming|first2=Paul|last3=Virasami|first3=Alex|last4=Michel|first4=Marie-Laure|last5=Sebire|first5=Neil J|last6=Costeloe|first6=Kate|last7=Carr|first7=Robert|last8=Klein|first8=Nigel|last9=Hayday|first9=Adrian|title=Interleukin-8 (CXCL8) production is a signatory T cell effector function of human newborn infants|journal=Nature Medicine|volume=20|issue=10|year=2014|pages=1206–1210|doi=10.1038/nm.3670|pmid= 25242415|s2cid=5849557}}
Education
Hayday was educated at Queens' College, Cambridge, where he was awarded a Bachelor of Arts degree in natural sciences (biochemistry) in 1978. He went on to complete his PhD in molecular virology of Polyomaviridae at Imperial College London in 1982.{{cite thesis |degree=PhD |first=Adrian Clive|last=Hayday |title=Structure and activity of integrated polyoma viral DNA in transformed rat cells |publisher=Imperial College London |year=1982 |url=http://catalogue.ulrls.lon.ac.uk/record=b1525087|oclc=930652868}}
Career and research
Hayday began studying immunology as a postdoctoral researcher in 1982 at Massachusetts Institute of Technology (MIT) supervised by Susumu Tonegawa,Adrian Hayday's {{ORCID|0000-0002-9495-5793}}{{cite journal|last1=Hayday|first1=A|title=Structure, organization, and somatic rearrangement of T cell gamma genes|journal=Cell|volume=40|issue=2|year=1985|pages=259–269|doi=10.1016/0092-8674(85)90140-0|pmid=3917858|s2cid=34582929}} where he identified the molecular basis of oncogene activation in Burkitt's lymphoma. Thereafter, he first described the genes defining gamma-delta T cells, an evolutionarily conserved yet wholly unanticipated set of lymphocytes. At Yale University, King's College London School of Medicine and the Francis Crick Institute, Hayday established that gamma-delta T cells are distinct from other T cells, commonly monitoring body-surface integrity rather than specific infections. Their rapid responses to tissue dysregulation offer protection from carcinogenesis, underpinning Hayday's and others' ongoing initiatives to employ the cells for immunotherapy.{{cite journal|last1=Kiyokawa|first1=Hiroaki|last2=Kineman|first2=Rhonda D|last3=Manova-Todorova|first3=Katia O|last4=Soares|first4=Vera C|last5=Hoffman|first5=Eric S|last6=Ono|first6=Masao|last7=Khanam|first7=Dilruba|last8=Hayday|first8=Adrian C|last9=Frohman|first9=Lawrence A|last10=Koff|first10=Andrew|title=Enhanced Growth of Mice Lacking the Cyclin-Dependent Kinase Inhibitor Function of p27Kip1|journal=Cell|volume=85|issue=5|year=1996|pages=721–732|doi=10.1016/S0092-8674(00)81238-6|pmid=8646780|doi-access=free}}
Awards and honours
Hayday has received numerous awards, including the William Clyde DeVane Medal, Yale's highest honour for scholarship and teaching. He was elected to head the British Society for Immunology (2005–09), and has formally counselled King's Health Partners, the Pasteur Institute, Kyoto University, the Max Planck Institute, the Allen Institute, MedImmune, the National Institutes of Health, the Wellcome Trust, and Cancer Research UK whose science committee he chairs. He was elected a Fellow of the Royal Society (FRS) in 2016.{{cite web|url=https://royalsociety.org/people/adrian-hayday-12874/ |title=Professor Adrian Hayday FRS |publisher=Royal Society |archivedate=2016-04-29 |archiveurl=https://web.archive.org/web/20160429122311/https://royalsociety.org/people/adrian-hayday-12874/ |location=London|author=Anon|year=2016 }} One or more of the preceding sentences incorporates text from the royalsociety.org website where: {{blockquote|"All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License." --{{cite web|url=https://royalsociety.org/about-us/terms-conditions-policies/ |title=Royal Society Terms, conditions and policies |accessdate=2016-03-09 |url-status=bot: unknown |archiveurl=https://web.archive.org/web/20150925220834/https://royalsociety.org/about-us/terms-conditions-policies/ |archivedate=2015-09-25 }}}}
He is an honorary member of the British Society for Immunology.{{Cite web|url=https://www.immunology.org/about-us/our-people/our-members/honorary-members|title=Honorary members | British Society for Immunology}}
References
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{{Francis Crick Institute}}
{{FRS 2016}}
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Category:Alumni of Queens' College, Cambridge
Category:Alumni of Imperial College London
Category:Academics of King's College London
Category:Fellows of the Academy of Medical Sciences (United Kingdom)
Category:Fellows of the Royal Society
Category:British immunologists
Category:Academics of the Francis Crick Institute
Category:Fellows of King's College London
Category:Searle Scholars Program recipients
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