Aliphatic aldoxime dehydratase
{{infobox enzyme
| Name = Aliphatic aldoxime dehydratase
| EC_number = 4.99.1.5
| CAS_number =
| GO_code =
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In enzymology, an aliphatic aldoxime dehydratase ({{EC number|4.99.1.5}}) is an enzyme that catalyzes the chemical reaction
:an aliphatic aldoxime an aliphatic nitrile + H2O
This dehydratase converts an aldoxime on an aliphatic substrate to a nitrile as the product structure with water as byproduct.
This enzyme belongs to the family of lyases, specifically the "catch-all" class of lyases that do not fit into any other sub-class. The systematic name of this enzyme class is aliphatic aldoxime hydro-lyase (aliphatic-nitrile-forming). Other names in common use include OxdA, and aliphatic aldoxime hydro-lyase.
See also
- D-amino acid oxidase, sometimes also referred to as OXDA
References
{{reflist|1}}
- {{cite journal | author = Kobayashi M | date = 2003 | title = Novel aldoxime dehydratase involved in carbon-nitrogen triple bond synthesis of Pseudomonas chlororaphis B23. Sequencing, gene expression, purification, and characterization | journal = J. Biol. Chem. | volume = 278 | pages = 29600–8 | pmid = 12773527 | doi = 10.1074/jbc.M211832200 | last2 = Hashimoto | first2 = Y | last3 = Konishi | first3 = K | last4 = Goda | first4 = M | last5 = Noguchi | first5 = T | last6 = Higashibata | first6 = H | last7 = Kobayashi | first7 = M | issue = 32 | doi-access = free }}
- {{cite journal |vauthors=Xie SX, Kato Y, Komeda H, Yoshida S, Asano Y | date = 2003 | title = A gene cluster responsible for alkylaldoxime metabolism coexisting with nitrile hydratase and amidase in Rhodococcus globerulus A-4 | journal = Biochemistry | volume = 42 | pages = 12056–66 | pmid = 14556637 | doi = 10.1021/bi035092u | issue = 41 | citeseerx = 10.1.1.513.2481 }}
- {{cite journal |vauthors=Kato Y, Yoshida S, Xie SX, Asano Y | date = 2004 | title = Aldoxime dehydratase co-existing with nitrile hydratase and amidase in the iron-type nitrile hydratase-producer Rhodococcus sp. N-771 | journal = J. Biosci. Bioeng. | volume = 97 | pages = 250–9 | pmid = 16233624 | issue = 4 | doi = 10.1016/S1389-1723(04)70200-5 }}
{{Enzymes}}
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Category:Enzymes of unknown structure
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