Allan Balmain

{{Short description|American academic}}

{{EngvarB|date=August 2017}}

{{Use dmy dates|date=August 2017}}

{{Infobox scientist

| honorific_prefix = Professor

| name = Allan Balmain

| honorific_suffix = {{postnominals|country=GBR|size=100%|FRS|FRSE}}

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| image = Allan-Balmain-FRS.jpg

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| caption = Balmain in 2015

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| fields = {{Plainlist|

  • Cancer{{Cite journal | pmid = 12610533| year = 2003| last1 = Balmain | first1 = A | authorlink1 = Allan Balmain| title = The genetics and genomics of cancer| journal = Nature Genetics| volume = 33 Suppl| issue = 3s| pages = 238–44| last2 = Gray| first2 = J| last3 = Ponder | first3 = B | authorlink3 = Bruce Ponder| doi = 10.1038/ng1107| s2cid = 8379885}}
  • Genetics{{Cite journal | doi = 10.1186/gb-2011-12-1-r5| title = Network analysis of skin tumor progression identifies a rewired genetic architecture affecting inflammation and tumor susceptibility| journal = Genome Biology| volume = 12| pages = R5| year = 2011| last1 = Quigley | first1 = D. A. | last2 = To | first2 = M. D. | last3 = Kim | first3 = I. J. | last4 = Lin | first4 = K. K. | last5 = Albertson | first5 = D. G. | last6 = Sjolund | first6 = J. | last7 = Pérez-Losada | first7 = J. S. | last8 = Balmain | first8 = A. | pmid = 21244661| pmc = 3091303| authorlink8 = Allan Balmain| url = https://cloudfront.escholarship.org/dist/prd/content/qt2hz2r67q/qt2hz2r67q.pdf | doi-access = free}} {{open access}}{{Cite journal | doi = 10.1016/S0092-8674(00)80127-0| title = TGFβ1 Inhibits the Formation of Benign Skin Tumors, but Enhances Progression to Invasive Spindle Carcinomas in Transgenic Mice| journal = Cell| volume = 86| issue = 4| pages = 531–542| year = 1996| last1 = Cui | first1 = W. | last2 = Fowlis | first2 = D. J. | last3 = Bryson | first3 = S. | last4 = Duffie | first4 = E. | last5 = Ireland | first5 = H. | last6 = Balmain | first6 = A. | last7 = Akhurst | first7 = R. J. | pmid = 8752208| s2cid = 18065761| doi-access = free }}{{Cite journal

| pmid = 8306319

| year = 1994

| last1 = Merritt

| first1 = A. J.

| title = The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice

| journal = Cancer Research

| volume = 54

| issue = 3

| pages = 614–7

| last2 = Potten

| first2 = C. S.

| last3 = Kemp

| first3 = C. J.

| last4 = Hickman

| first4 = J. A.

| last5 = Balmain

| first5 = A

| last6 = Lane

| first6 = D. P.

| last7 = Hall

| first7 = P. A.

}}}}

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| alma_mater = University of Glasgow

| thesis_title = Studies in the diterpenoid field

| thesis_url = http://www.worldcat.org/oclc/181893750

| thesis_year = 1969

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  • FRS (2015){{cite web |url=https://royalsociety.org/people/fellowship/2015/allan-balmain/ |title = Professor Allan Balmain FRS |publisher=The Royal Society |archivedate=2015-05-02 |archiveurl=https://web.archive.org/web/20150502130846/https://royalsociety.org/people/fellowship/2015/allan-balmain/ |location=London}}
  • FRSE (1995)}}

| website = {{Plainlist|

  • {{URL|profiles.ucsf.edu/allan.balmain}}
  • {{URL|cancer.ucsf.edu/research/balmain-lab}}
  • {{URL|http://cancer.ucsf.edu/people/profiles/balmain_allan.3777}}}}

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}}Allan Balmain is an American academic who is Barbara Bass Bakar Distinguished Professor of Cancer Genetics at the University of California, San Francisco (UCSF).{{Cite journal

| pmid = 11586292

| year = 2001

| last1 = Derynck

| first1 = R

| title = TGF-beta signaling in tumor suppression and cancer progression

| journal = Nature Genetics

| volume = 29

| issue = 2

| pages = 117–29

| last2 = Akhurst

| first2 = R. J.

| last3 = Balmain

| first3 = A

| doi = 10.1038/ng1001-117

| s2cid = 9923320

}}{{Cite journal

| pmid = 3014349

| year = 1986

| last1 = Quintanilla

| first1 = M

| title = Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis

| journal = Nature

| volume = 322

| issue = 6074

| pages = 78–80

| last2 = Brown

| first2 = K

| last3 = Ramsden

| first3 = M

| last4 = Balmain

| first4 = A

| doi = 10.1038/322078a0

| bibcode = 1986Natur.322...78Q

| s2cid = 4353576

}}{{Scopus|id=7005789638}}{{Cite journal | doi = 10.1002/mc.2940070303| title = How many mutations are required for tumorigenesis? Implications from human cancer data| journal = Molecular Carcinogenesis| volume = 7| issue = 3| pages = 139–146| year = 1993| last1 = Balmain | first1 = A. | last2 = Barrett | first2 = J. C. | last3 = Moses | first3 = H. | last4 = Renan | first4 = M. J. | pmid = 8489711| s2cid = 29456469}}{{Cite journal | doi = 10.1038/307658a0| title = Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas| journal = Nature| volume = 307| issue = 5952| pages = 658–660| year = 1984| last1 = Balmain | first1 = A. | last2 = Ramsden | first2 = M. | last3 = Bowden | first3 = G. T. | last4 = Smith | first4 = J. | pmid = 6694757| bibcode = 1984Natur.307..658B| s2cid = 4254723}}

Education

Balmain was educated at the University of Glasgow where he was awarded a Bachelor of Science degree in chemistry in 1966, followed by a PhD on the organic chemistry of terpenoids in 1969.{{cite web|archiveurl=https://web.archive.org/web/20130206185611/http://cancer.ucsf.edu/people/profiles/balmain_allan.3777|archivedate=2013-02-06|url=http://cancer.ucsf.edu/people/profiles/balmain_allan.3777|publisher=University of California, San Francisco|title=Allan Balmain, PhD, FRSE}}

Awards and honours

Balmain was elected a Fellow of the Royal Society (FRS) in 2015. His certificate of election reads: {{quote|Allan Balmain has pioneered the use of the mouse as a model system for understanding the complexity of cancer at a genetic, molecular and cellular level. Through his novel and creative experiments he established the first molecular link between cancer initiation and carcinogen exposure, identified how specific genetic events lead to malignant progression and made major advances in our understanding of cancer susceptibility. Balmain's wide-ranging, innovative use of mouse genetics has generated new approaches for visualizing the genetic architecture of cancer pathways and the roles of complex network interactions in determining an individual's cancer susceptibility.}}

Balmain was also elected a Fellow of the Royal Society of Edinburgh (FRSE) in 1995.

References