Alopecia neoplastica

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Alopecia neoplastica may present as a scarring alopecia, appearing anywhere on the scalp, and it has been described with cutaneous metastasis from breast, gastric, lung, renal and pancreatic carcinomas.{{cite book |author =Rapini, Ronald P. |author2 =Bolognia, Jean L. |author3 =Jorizzo, Joseph L. |title=Dermatology: 2-Volume Set |publisher=Mosby |location=St. Louis |year=2007 |pages=1899 |isbn=978-1-4160-2999-1 }}

Signs and symptoms

Alopecia neoplastica usually presents as a nodule, plaque, patch, or ulceration on the scalp.{{cite journal | last1=Paolino | first1=G. | last2=Pampena | first2=R. | last3=Grassi | first3=S. | last4=Mercuri | first4=S.R. | last5=Cardone | first5=M. | last6=Corsetti | first6=P. | last7=Moliterni | first7=E. | last8=Muscianese | first8=M. | last9=Rossi | first9=A. | last10=Frascione | first10=P. | last11=Longo | first11=C. | title=Alopecia neoplastica as a sign of visceral malignancies: a systematic review | journal=Journal of the European Academy of Dermatology and Venereology | volume=33 | issue=6 | date=2019 | issn=0926-9959 | doi=10.1111/jdv.15498 | pages=1020–1028| pmid=30767283 | s2cid=73423215 }}

Causes

Alopecia neoplastica can come from tumors that are malignant or benign.{{cite journal | last1=Flanagan | first1=Kelly E. | last2=Burns | first2=Laura J. | last3=Pathoulas | first3=James T. | last4=Walker | first4=Chloe J. | last5=Pupo Wiss | first5=Isabel | last6=Cornejo | first6=Kristine M. | last7=Senna | first7=Maryanne M. | title=Primary Alopecia Neoplastica: A Novel Case Report and Literature Review | journal=Skin Appendage Disorders | publisher=S. Karger AG | volume=7 | issue=6 | year=2021 | issn=2296-9195 | doi=10.1159/000516650 | pages=499–509| pmid=34901185 | pmc=8613616 }} The most common cancer linked to alopecia neoplastica was found to be GI cancer, followed by breast cancer.

Epidemiology

According to one study, 53.7% of patients with alopecia neoplastica were women, compared to 46.3% of men. 59 was the median age at onset.

See also

References

{{reflist}}

Further reading

  • {{cite journal | last=Cohen | first=Philip R. | title=Primary alopecia neoplastica versus secondary alopecia neoplastica: a new classification for neoplasm-associated scalp hair loss | journal=Journal of Cutaneous Pathology | publisher=Wiley | volume=36 | issue=8 | date=2009-06-22 | issn=0303-6987 | doi=10.1111/j.1600-0560.2008.01187.x | pages=917–918 | pmid=19586507 | s2cid=13055580 | ref=none}}
  • {{cite journal | last1=Kim | first1=Jung-Hee | last2=Kim | first2=Min-Joong | last3=Sim | first3=Woo-Young | last4=Lew | first4=Bark-Lynn | title=Alopecia Neoplastica due to Gastric Adenocarcinoma Metastasis to the Scalp, Presenting as Alopecia: A Case Report and Literature Review | journal=Annals of Dermatology | publisher=Korean Dermatological Association and The Korean Society for Investigative Dermatology | volume=26 | issue=5 | year=2014 | pages=624–627 | issn=1013-9087 | doi=10.5021/ad.2014.26.5.624 | pmid=25324657 | pmc=4198592 | ref=none}}