Alseroxylon

{{Short description|Pharmaceutical drug}}

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| verifiedrevid = 486387027

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| image = Reserpine.svg

| caption = Reserpine, the major component of alseroxylon

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| CAS_number = 8001-95-4

| ATC_prefix = C02

| ATC_suffix = AA03

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| UNII = H192N84N1G

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| ChEMBL = 1201454

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| DrugBank = DB00386

| index2_label = active moiety

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| CAS_number2 = 8063-17-0

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| UNII2 = H192N84N1G

| chemical_formula = Varies

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Alseroxylon (Rautensin, Rauwiloid) is a norepinephrine reuptake inhibitor that has been investigated in the treatment of hypertension{{cite journal | vauthors = Green RS, Davolos D | title = A long-term study of the effect of crude Rauwolfia serpentina and of its alseroxylon fraction in patients with hypertension | journal = The American Journal of Medicine | volume = 20 | issue = 5 | pages = 760–73 | date = May 1956 | pmid = 13313574 | doi = 10.1016/0002-9343(56)90158-9 }} and angina pectoris and as a sedative in psychoses.{{DrugBank|DB00386}} It was at one time approved for use in the United States, but has since been discontinued.{{cite book | title = Approved Drug Products with Therapeutic Equivalence Evaluations | work = FDA Orange Book | edition = 33rd | date = 2013}}

Alseroxylon is a purified fat-soluble extract of the root of Rauvolfia serpentina, containing reserpine and other nonadrenolytic amorphous alkaloids.

References