Altizide

{{Chembox

| Verifiedfields = changed

| Watchedfields = changed

| verifiedrevid = 456682206

| ImageFile = Altizide.svg

| ImageSize = 250

| IUPACName = (3R)-3-[(Allylsulfanyl)methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

| OtherNames = {{unbulleted list|Althiazide|CB 8093|P 1779|Altizidum}}

| Section1 = {{Chembox Identifiers

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = GI8CB72B0D

| ChEMBL_Ref = {{ebicite|changed|EBI}}

| ChEMBL = 599870

| PubChem = 6604323

| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}

| ChemSpiderID = 5036613

| SMILES = O=S(=O)(c1c(Cl)cc2c(c1)S(=O)(=O)N[C@@H](N2)CSC\C=C)N

| InChI = 1/C11H14ClN3O4S3/c1-2-3-20-6-11-14-8-4-7(12)9(21(13,16)17)5-10(8)22(18,19)15-11/h2,4-5,11,14-15H,1,3,6H2,(H2,13,16,17)/t11-/m1/s1

| InChIKey = VGLGVJVUHYTIIU-LLVKDONJBT

| StdInChI_Ref = {{stdinchicite|correct|chemspider}}

| StdInChI = 1S/C11H14ClN3O4S3/c1-2-3-20-6-11-14-8-4-7(12)9(21(13,16)17)5-10(8)22(18,19)15-11/h2,4-5,11,14-15H,1,3,6H2,(H2,13,16,17)/t11-/m1/s1

| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}

| StdInChIKey = VGLGVJVUHYTIIU-LLVKDONJSA-N

| CASNo_Ref = {{cascite|changed|??}}

| CASNo = 5588-16-9

| PubChem2 = 2122

| KEGG_Ref = {{keggcite|correct|kegg}}

| KEGG = D02838

| SMILES2 = C=CCSCC1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl

}}

| Section2 = {{Chembox Properties

| Formula = C11H14ClN3O4S3

| MolarMass = 383.89456

| Appearance =

| Density = 1.502 g/mL

| MeltingPt =

| BoilingPtC = 625.8

| Solubility =

}}

| Section3 = {{Chembox Hazards

| MainHazards =

| FlashPt =

| AutoignitionPt =

}}

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Altizide is a thiazide diuretic. In combination with spironolactone it is sold under the brand name of Aldactacine and Aldactazine by Pfizer and other names by other companies.{{cite web|title=Altizide|url=https://www.drugs.com/international/altizide.html|website=drugs.com}}{{cite journal|title=Clinical update: spironolactone and altizide as monotherapy in systemic hypertension|journal=The American Journal of Cardiology|volume=65|issue=23|pages=20K–23K|pmid=2191585|year=1990|last1=Dueymes|first1=J. M|doi=10.1016/0002-9149(90)91272-8}}

References