Aluminium sesquichlorohydrate

{{Short description|Chemical compound}}

{{Infobox drug

| drug_name = Aluminium sesquichlorohydrate

| type =

| image =

| alt =

| caption =

| MedlinePlus =

| licence_EU =

| licence_US =

| pregnancy_AU =

| pregnancy_US =

| pregnancy_category =

| legal_status =

| CAS_number = 1327-41-9

| PubChemSubstance = 347911118

| DrugBank = DB11108

| UNII = UCN889409V

| molecular_weight = 97.46

| molecular_weight_comment = g/mol

}}

Aluminium sesquichlorohydrate is an aluminium salt that is used as an antiperspirant agent, a deodorant agent, and a cosmetic astringent. Aluminium sesquichlorohydrate works by physically blocking eccrine sweat glands.{{cite journal | vauthors = Innocenzi D, Ruggero A, Francesconi L, Lacarrubba F, Nardone B, Micali G | title = An open-label tolerability and efficacy study of an aluminum sesquichlorohydrate topical foam in axillary and palmar primary hyperhidrosis | journal = Dermatologic Therapy | volume = 21 | pages = S27-30 | date = July 2008 | issue = Suppl 1 | pmid = 18727813 | doi = 10.1111/j.1529-8019.2008.00199.x | s2cid = 6247172 }}{{Cite web|url=https://www.drugbank.ca/drugs/DB11108|title=Aluminum sesquichlorohydrate|date=November 3, 2015|website=DrugBank|access-date=November 18, 2018|archive-date=November 19, 2018|archive-url=https://web.archive.org/web/20181119132631/https://www.drugbank.ca/drugs/DB11108|url-status=live}}{{Cite web|url=https://pubchem.ncbi.nlm.nih.gov/substance/347911118|title=Substance Record for SID 347911118 - Aluminum Sesquichlorohydrate|date=November 3, 2018|work=PubChem|publisher=U.S. National Library of Medicine|access-date=November 18, 2018|archive-date=May 4, 2024|archive-url=https://web.archive.org/web/20240504062700/https://pubchem.ncbi.nlm.nih.gov/substance/347911118#section=Information-Sources|url-status=live}}{{Cite web|url=https://fdasis.nlm.nih.gov/srs/unii/UCN889409V|title=Search Substance Registration System - UCN889409V|website=FDA Substance Registration System|access-date=November 18, 2018|archive-date=June 11, 2020|archive-url=https://web.archive.org/web/20200611020420/https://fdasis.nlm.nih.gov/srs/unii/UCN889409V|url-status=dead}}{{Cite web|url=https://chem.nlm.nih.gov/chemidplus/unii/UCN889409V|title=Substance Name: Aluminum sesquichlorohydrate [USAN:USP]|website=ChemID Plus|access-date=November 18, 2018|archive-date=November 19, 2018|archive-url=https://web.archive.org/web/20181119091956/https://chem.nlm.nih.gov/chemidplus/unii/UCN889409V|url-status=live}}

The United States Food and Drug Administration considers the use of aluminium sesquichlorohydrate in antiperspirants to be safe and it is permitted in concentrations up to 25%.[https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=350.10 Code of Federal Regulations Title 21] {{CodeFedReg|21|350|10}}