Andrea Baccarelli

Baccarelli graduated cum laude with a medical degree from the University of Perugia, Italy in 1995, obtained his Master of Science in Epidemiology from the University of Turin, Italy, and his Ph.D. in Occupational Health and Industrial Hygiene from the Universita' degli Studi di Milano, Italy, in 2003.{{Cite web|date=2018-08-21|title=Una vita per la ricerca, Il Baiocco d'oro a Baccarelli|url=https://tuttoggi.info/una-vita-per-la-ricerca-il-baiocco-doro-a-baccarelli/472791/|access-date=2021-10-22|website=Tuttoggi|language=it-IT}}

He completed his residency in endocrinology at the University of Milan and his postdoctoral fellowship at the National Cancer Institute's Division of Cancer Epidemiology and Genetics (2000–2004).{{Cite web|title=Andrea Baccarelli {{!}} Columbia Public Health|url=https://www.publichealth.columbia.edu/people/our-faculty/ab4303|access-date=2021-10-21|website=www.publichealth.columbia.edu}}

Baccarelli has served as the Dean of the Faculty at the Harvard T.H. Chan School of Public Health since January 2024. He previously taught at the Harvard Chan School as the Mark and Catherine Winkler Associate Professor of Environmental Epigenetics from 2010 to 2016.{{Cite web |last=gazetteterrymurphy |date=2023-10-11 |title=Next dean of Harvard T.H. Chan School of Public Health announced |url=https://news.harvard.edu/gazette/story/2023/10/next-dean-of-harvard-t-h-chan-school-of-public-health-announced/ |access-date=2024-01-18 |website=Harvard Gazette |language=en-US}} Baccarelli, as Dean of the Harvard T.H. Chan School of Public Health, has initiated comprehensive reviews of faculty and academic programs aimed at enhancing rigor and quality.{{Cite web |last=Belkin |first=Douglas |title=Harvard’s $9 Billion Scramble to Avoid Becoming the Next Columbia |url=https://www.wsj.com/us-news/education/harvard-alan-garber-trump-funding-columbia-f497da52 |access-date=2025-04-09 |website=WSJ |language=en-US}} Additionally, he has emphasized the importance of cultivating a pluralistic institutional culture aligned with the school's core values and accountable practices.{{Cite web |last=Belkin |first=Douglas |title=Harvard’s $9 Billion Scramble to Avoid Becoming the Next Columbia |url=https://www.wsj.com/us-news/education/harvard-alan-garber-trump-funding-columbia-f497da52 |access-date=2025-04-09 |website=WSJ |language=en-US}}

He also served as Professor and Chair of the Department of Environmental Health Sciences at the Columbia University Mailman School of Public Health from 2016 to 2023.{{Cite web |date=2021-05-03 |title=Air pollution spikes may impair older men's thinking, study finds |url=http://www.theguardian.com/environment/2021/may/03/air-pollution-spikes-may-impair-older-mens-thinking-study-finds |access-date=2021-10-21 |website=the Guardian |language=en}}{{Cite web |date=2021-05-21 |title="C'è una relazione tra inquinamento e capacità cognitive" |url=https://www.repubblica.it/green-and-blue/2021/05/21/news/andrea_baccarelli_columbia_university_c_e_una_relazione_tra_inquinamento_e_capacita_cognitive_-301963733/ |access-date=2021-10-21 |website=la Repubblica |language=it}} While at Columbia, he led the NIEHS Center for Environmental Health, which brought together scientists, advocates, community organizations and the public to understand health concerns caused by environmental exposures.{{Cite web |date=2023-01-29 |title=Andrea Baccarelli – The Data Science Institute at Columbia University |url=https://datascience.columbia.edu/people/andrea-baccarelli/ |access-date=2024-01-18 |archive-url=https://web.archive.org/web/20230129163148/https://datascience.columbia.edu/people/andrea-baccarelli/ |archive-date=2023-01-29 }}

Baccarelli's research has pioneered the field of public health epigenetics, which explores how environmental factors can modify gene expression without changing the DNA sequence.{{Cite web |last=Kirkpatrick |first=Bailey |date=2016-07-28 |title=3 Pioneering Epigenetic Labs: Exploring the People and Discoveries that Transcend the Lab Walls |url=http://www.whatisepigenetics.com/3-pioneering-epigenetic-labs-exploring-the-people-and-discoveries-that-transcend-the-lab-walls/ |access-date=2023-06-22 |website=What is Epigenetics? |language=en}} His studies have demonstrated that air pollution can alter the epigenome, leading to changes in gene regulation that may contribute to the development of diseases such as cardiovascular disorders and neurodegenerative conditions.{{Cite web |last=Kirkpatrick |first=Bailey |date=2017-05-30 |title=B Vitamins Protect Against Harmful Epigenetic Effects of Air Pollution |url=http://www.whatisepigenetics.com/b-vitamins-protect-harmful-epigenetic-effects-air-pollution/ |access-date=2023-06-22 |website=What is Epigenetics? |language=en}}{{Cite web |title=How our environment is making us sick – and what we can do about it |url=https://www.newscientist.com/article/mg25333710-800-how-our-environment-is-making-us-sick-and-what-we-can-do-about-it/ |access-date=2023-06-22 |website=New Scientist |language=en-US}}

Baccarelli conducted research showing that short-term exposure to air pollution, including levels considered "acceptable," can impair cognitive ability in the elderly.{{Cite news |last=Bakalar |first=Nicholas |date=2021-05-17 |title=Air Pollution Takes a Toll on the Brain |language=en-US |work=The New York Times |url=https://www.nytimes.com/2021/05/17/well/mind/pollution-brain-aspirin.html |access-date=2023-06-22 |issn=0362-4331}}{{Cite web |date=2021-05-04 |title=Short-term exposure to air pollution may impede cognition, Aspirin could help: Study |url=https://in.style.yahoo.com/short-term-exposure-air-pollution-025326643.html |access-date=2023-06-22 |website=in.style.yahoo.com |language=en-CA}}{{Cite news |last1=Sample |first1=Ian |date=2021-05-03 |title=Air pollution spikes may impair older men's thinking, study finds |language=en-GB |work=The Guardian |url=https://www.theguardian.com/environment/2021/may/03/air-pollution-spikes-may-impair-older-mens-thinking-study-finds |access-date=2023-06-22 |issn=0261-3077}} Baccarelli also found that the use of nonsteroidal anti-inflammatory drugs such as aspirin partially protected against the negative cognitive effects of pollution.{{Cite news |last1=Sample |first1=Ian |date=2021-05-03 |title=Air pollution spikes may impair older men's thinking, study finds |language=en-GB |work=The Guardian |url=https://www.theguardian.com/environment/2021/may/03/air-pollution-spikes-may-impair-older-mens-thinking-study-finds |access-date=2023-06-22 |issn=0261-3077}} He also conducted research showing that ambient air pollution is associated with an increased risk of osteoporosis and bone fractures in older individuals.{{Cite web |title=Does air pollution affect osteoporosis? Science finds a connection |url=https://fortune.com/well/2023/02/27/air-pollution-osteoporosis/ |access-date=2023-06-22 |website=Fortune Well |language=en}}{{Cite web |title=Air pollution speeds up bone loss from osteoporosis: Study – ET HealthWorld |url=https://health.economictimes.indiatimes.com/news/industry/air-pollution-speeds-up-bone-loss-from-osteoporosis-study/98147830 |access-date=2023-06-22 |website=ETHealthworld.com |language=en}}

In April 2024, Baccarelli authored an opinion article in The Boston Globe, highlighting the scientific advancements related to the exposome, which represents the sum of all environmental and behavioral exposures affecting human health. The article emphasized the potential of DNA methylation and epigenetic analysis to improve public health by identifying and preventing harmful environmental exposures through advanced diagnostic methods.{{Cite web |last=Baccarelli |first=Andrea |title=Public health’s new frontier: unlocking the exposome |url=https://www.bostonglobe.com/2024/04/04/opinion/public-health-testing-toxic-exposure/ |date=2024-04-04 |access-date=2025-04-09 |work=The Boston Globe |language=en-US}}

In 2020, Baccarelli was elected to the National Academy of Medicine.{{Cite web|date=2020-10-16|title=Five Elected to the National Academy of Medicine|url=https://www.cuimc.columbia.edu/news/five-elected-national-academy-medicine|access-date=2021-10-21|website=Columbia University Irving Medical Center|language=en}} He has also been an active member of the International Society of Environmental Epidemiology, serving as the society's president from 2022 to 2023.{{Cite web |title=Leadership – International Society for Environmental Epidemiology |url=https://www.iseepi.org/leadership.php |access-date=2024-01-18 |website=www.iseepi.org}}

Baccarelli was recognized as the “Person of the Year” by the City of Perugia, Italy.{{Cite web|title=Perugia consegna il Baiocco d'oro al professor Andrea Baccarelli: "È uno dei nostri figli migliori"|url=http://www.umbria24.it/attualita/perugia-consegna-baiocco-doro-al-professor-andrea-baccarelli-uno-dei-nostri-figli-migliori|access-date=2021-10-22|website=Umbria24.it|date=21 August 2018 |language=it-IT}}{{Cite web|title=Baiocco d'Oro al super professore perugino: "Oggi la città premia uno dei suoi figli migliori"|url=https://www.perugiatoday.it/attualita/baiocco-d-oro-professore-perugino-andrea-baccarelli.html|access-date=2021-10-22|website=PerugiaToday|language=it}}

In 2024, he was honored as the National Institute of Environmental Health Sciences Hans L. Falk Memorial Lecture Award recipient, recognizing his contributions to environmental health sciences.{{Cite web |title=Falk lecturer discusses new methods to detect environmental exposures |url=https://factor.niehs.nih.gov/2024/12/science-highlights/detecting-env-exposure |access-date=2024-12-19 |website=National Institute of Environmental Health Sciences |language=en}}

• {{Cite journal|last1=Baccarelli|first1=Andrea|last2=Bollati|first2=Valentina|date=2009|title=Epigenetics and environmental chemicals|journal=Current Opinion in Pediatrics|language=en|volume=21|issue=2|pages=243–251|doi=10.1097/MOP.0b013e32832925cc|pmid=19663042 |pmc=3035853 |issn=1040-8703|doi-access=free}}
• {{Cite journal|last1=Marioni|first1=Riccardo E|last2=Shah|first2=Sonia|last3=McRae|first3=Allan F|last4=Chen|first4=Brian H|last5=Colicino|first5=Elena|last6=Harris|first6=Sarah E|last7=Gibson|first7=Jude|last8=Henders|first8=Anjali K|last9=Redmond|first9=Paul|last10=Cox|first10=Simon R|last11=Pattie|first11=Alison|date=2015|title=DNA methylation age of blood predicts all-cause mortality in later life|journal=Genome Biology|language=en|volume=16|issue=1|pages=25|doi=10.1186/s13059-015-0584-6|issn=1474-760X|pmc=4350614|pmid=25633388 |doi-access=free }}
• {{Cite journal|last1=Baccarelli|first1=Andrea|last2=Wright|first2=Robert O.|last3=Bollati|first3=Valentina|last4=Tarantini|first4=Letizia|last5=Litonjua|first5=Augusto A.|last6=Suh|first6=Helen H.|last7=Zanobetti|first7=Antonella|last8=Sparrow|first8=David|last9=Vokonas|first9=Pantel S.|last10=Schwartz|first10=Joel|date=2009|title=Rapid DNA Methylation Changes after Exposure to Traffic Particles|journal=American Journal of Respiratory and Critical Care Medicine|language=en|volume=179|issue=7|pages=572–578|doi=10.1164/rccm.200807-1097OC|issn=1073-449X|pmc=2720123|pmid=19136372}}
• {{Cite journal|last1=Bollati|first1=Valentina|last2=Baccarelli|first2=Andrea|last3=Hou|first3=Lifang|last4=Bonzini|first4=Matteo|last5=Fustinoni|first5=Silvia|last6=Cavallo|first6=Domenico|last7=Byun|first7=Hyang-Min|last8=Jiang|first8=Jiayi|last9=Marinelli|first9=Barbara|last10=Pesatori|first10=Angela C.|last11=Bertazzi|first11=Pier A.|date=2007-02-01|title=Changes in DNA Methylation Patterns in Subjects Exposed to Low-Dose Benzene|url=http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-5472.CAN-06-2995|journal=Cancer Research|language=en|volume=67|issue=3|pages=876–880|doi=10.1158/0008-5472.CAN-06-2995|pmid=17283117 |issn=0008-5472|hdl=11383/1708214|s2cid=15163723 |hdl-access=free}}
• {{Cite journal|last1=Levine|first1=Morgan E.|last2=Lu|first2=Ake T.|last3=Quach|first3=Austin|last4=Chen|first4=Brian H.|last5=Assimes|first5=Themistocles L.|last6=Bandinelli|first6=Stefania|last7=Hou|first7=Lifang|last8=Baccarelli|first8=Andrea A.|last9=Stewart|first9=James D.|last10=Li|first10=Yun|last11=Whitsel|first11=Eric A.|date=2018-04-18|title=An epigenetic biomarker of aging for lifespan and healthspan|journal=Aging|language=en|volume=10|issue=4|pages=573–591|doi=10.18632/aging.101414|issn=1945-4589|pmc=5940111|pmid=29676998}}
• {{Cite journal |last1=Kupsco |first1=Allison |last2=Kioumourtzoglou |first2=Marianthi-Anna |last3=Just |first3=Allan C |last4=Amarasiriwardena |first4=Chitra |last5=Estrada-Gutierrez |first5=Guadalupe |last6=Cantoral |first6=Alejandra |last7=Sanders |first7=Alison P |last8=Braun |first8=Joseph M |last9=Svensson |first9=Katherine |last10=Brennan |first10=Kasey JM |last11=Oken |first11=Emily |last12=Wright |first12=Robert O |last13=Baccarelli |first13=Andrea A. |last14=Téllez-Rojo |first14=Maria M |date=March 2019 |title=Prenatal metal concentrations and childhood cardio-metabolic risk using Bayesian Kernel Machine Regression to assess mixture and interaction effects. |journal=Epidemiology |volume=30 |issue=2 |pages=263–273 |doi=10.1097/EDE.0000000000000962 |issn=1044-3983 |pmc=6402346 |pmid=30720588}}
• {{Cite journal |last1=Turner |first1=Michelle C. |last2=Andersen |first2=Zorana J. |last3=Baccarelli |first3=Andrea |last4=Diver |first4=W. Ryan |last5=Gapstur |first5=Susan M. |last6=Pope |first6=C. Arden |last7=Prada |first7=Diddier |last8=Samet |first8=Jonathan |last9=Thurston |first9=George |last10=Cohen |first10=Aaron |date=November 2020 |title=Outdoor air pollution and cancer: An overview of the current evidence and public health recommendations |journal=CA: A Cancer Journal for Clinicians |language=en |volume=70 |issue=6 |pages=460–479 |doi=10.3322/caac.21632 |issn=0007-9235 |pmc=7904962 |pmid=32964460}}
• {{Cite journal |last1=Bell |first1=Christopher G. |last2=Lowe |first2=Robert |last3=Adams |first3=Peter D. |last4=Baccarelli |first4=Andrea A. |last5=Beck |first5=Stephan |last6=Bell |first6=Jordana T. |last7=Christensen |first7=Brock C. |last8=Gladyshev |first8=Vadim N. |last9=Heijmans |first9=Bastiaan T. |last10=Horvath |first10=Steve |last11=Ideker |first11=Trey |last12=Issa |first12=Jean-Pierre J. |last13=Kelsey |first13=Karl T. |last14=Marioni |first14=Riccardo E. |last15=Reik |first15=Wolf |date=2019-11-25 |title=DNA methylation aging clocks: challenges and recommendations |journal=Genome Biology |language=en |volume=20 |issue=1 |pages=249 |doi=10.1186/s13059-019-1824-y |doi-access=free |issn=1474-760X |pmc=6876109 |pmid=31767039}}
• {{Cite journal |last1=Wu |first1=Haotian |last2=Eckhardt |first2=Christina M. |last3=Baccarelli |first3=Andrea A. |date=May 2023 |title=Molecular mechanisms of environmental exposures and human diseases |journal=Nature Reviews Genetics |volume=24 |issue=5 |pages=332–344 |doi=10.1038/s41576-022-00569-3 |issn=1471-0056 |pmid=36717624|pmc=10562207 }}
• {{Cite journal |last1=Piscitelli |first1=Prisco |last2=Miani |first2=Alessandro |last3=Setti |first3=Leonardo |last4=De Gennaro |first4=Gianluigi |last5=Rodo |first5=Xavier |last6=Artinano |first6=Begona |last7=Vara |first7=Elena |last8=Rancan |first8=Lisa |last9=Arias |first9=Javier |last10=Passarini |first10=Fabrizio |last11=Barbieri |first11=Pierluigi |last12=Pallavicini |first12=Alberto |last13=Parente |first13=Alessandro |last14=D'Oro |first14=Edoardo Cavalieri |last15=De Maio |first15=Claudio |date=August 2022 |title=The role of outdoor and indoor air quality in the spread of SARS-CoV-2: Overview and recommendations by the research group on COVID-19 and particulate matter (RESCOP commission) |journal=Environmental Research |volume=211 |pages=113038 |doi=10.1016/j.envres.2022.113038 |issn=0013-9351 |pmc=8881809 |pmid=35231456|bibcode=2022ER....211k3038P }}
• Peters A, Nawrot TS, Baccarelli AA. [https://www.cell.com/cell/pdf/S0092-8674(21)00086-6.pdf Hallmarks of environmental insults]. Cell. 2021;184(6):1455–1468.

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Category:1970 births

Category:Living people

Category:Members of the National Academy of Medicine

Category:American endocrinologists

Category:Italian endocrinologists

Category:Public health doctors

Category:Epigeneticists