Angela Casini
{{short description|Medicinal and inorganic chemist}}
{{Infobox scientist
| name = Angela Casini
| alma_mater = University of Florence
| workplaces = Technical University of Munich
University of Groningen
| awards = European Medal for Bio-Inorganic Chemistry
}}
Angela Casini is a medicinal and inorganic chemist who works on metal-based compounds as therapeutic agents. She was awarded the 2012 European Medal for Bio-Inorganic Chemistry and made the 2019 American Chemical Society Inorganic Lecturer.
Early life and education
{{Cite journal|last1=Gabbiani|first1=Chiara|last2=Casini|first2=Angela|last3=Messori|first3=Luigi|date=2007-03-01|title=Gold(III) compounds as anticancer drugs|journal=Gold Bulletin|language=en|volume=40|issue=1|pages=73–81|doi=10.1007/BF03215296|issn=2190-7579|doi-access=free}} She earned her PhD in chemical sciences at the University of Florence in 2004.{{Cite web|url=https://www.cardiff.ac.uk/people/view/104658-casini-angela|title=Professor Angela Casini - People|last1=Medicinal|first1=Professor Angela Casini Chair of|last2=Chemistry|first2=Bioinorganic|website=Cardiff University|language=en|access-date=2019-08-26}} She was a postdoctoral fellow at the University of Pisa, where she worked on the mechanisms by which metal-complexes that are used as anti-cancer agents activate. She used both spectroscopy, including mass spectrometry imaging, and molecular biology.
Research and career
Angela Casini joined the École Polytechnique Fédérale de Lausanne as a Principal Investigator in 2008.{{Cite journal|last1=Casini|first1=Angela|last2=Woods|first2=Benjamin|last3=Wenzel|first3=Margot|date=2017-12-18|title=The Promise of Self-Assembled 3D Supramolecular Coordination Complexes for Biomedical Applications|journal=Inorganic Chemistry|language=en|volume=56|issue=24|pages=14715–14729|doi=10.1021/acs.inorgchem.7b02599|pmid=29172467|issn=0020-1669|doi-access=free}} She moved to the University of Groningen in 2011, where she was made a Rosalind Franklin Fellow.{{Cite web|url=https://www.ias.tum.de/en/alumni-fellows/casini-angela/|title=Institute for Advanced Study (IAS): Casini, Angela|website=www.ias.tum.de|access-date=2019-08-26}} She was made a Chair of Medicinal Chemistry at Cardiff University in 2015, and has served as Director of Postgraduate Teaching from 2018.{{Cite web|url=https://www.cardiff.ac.uk/news/view/118710-the-school-of-chemistry-welcomes-new-staff-member-professor-angela-casini|title=The School of Chemistry welcomes new staff member Professor Angela Casini|website=Cardiff University|language=en|access-date=2019-08-26}} She spent 2016 as a visiting professor at the Technical University of Munich.
= Awards and honours =
Her awards and honours include;
- 2012 European Medal for Bio-Inorganic Chemistry{{Cite web|url=http://www.bioinorganic-chemistry.org/eurobic/medal.html|title=EuroBIC|website=www.bioinorganic-chemistry.org|access-date=2019-08-26}}
- 2014 Gordon Research Conference Early Career Investigator{{Cite web|url=https://www.grc.org/metals-in-medicine-conference/2014/|title=2014 Metals in Medicine Conference GRC|website=www.grc.org|access-date=2019-08-26}}
- 2014 Thomson Reuters World's Most Influential Scientific Mind{{Cite web|url=https://metallomics2017.univie.ac.at/conference-program/invited-speakers/angela-casini/|title=Angela Casini|website=metallomics2017.univie.ac.at|language=en|access-date=2019-08-26}}
- 2016 Elected to the Young Academy of Europe{{Cite web|url=http://yacadeuro.org/angela-casini/|title=Angela Casini – Young Academy of Europe|date=18 December 2016 |language=en-US|access-date=2019-08-26}}
- 2018 Burghausen Diamond of Chemistry Award{{Cite web|url=https://www.tum.de/en/studinews/issue-052013/show/article/35060/|title=Burghausen Chemistry Award for Angela Casini|website=www.tum.de|language=en|access-date=2019-08-26}}{{Cite web|url=https://www.tum.de/en/studinews/issue-052013/show/article/35060/|title=Burghausen Chemistry Award for Angela Casini|website=www.tum.de|language=en|access-date=2019-08-26}}
- 2019 American Chemical Society Inorganic Lectureship Award{{Cite web|url=https://axial.acs.org/2019/03/12/angela-casini-receives-2019-inorganic-chemistry-lectureship-award/|title=Angela Casini Receives 2019 Inorganic Chemistry Lectureship Award|date=2019-03-12|website=ACS Axial|language=en-US|access-date=2019-08-26}}{{Cite web|url=https://www.cardiff.ac.uk/news/view/1504236-prof-angela-casini-wins-2019-inorganic-chemistry-lectureship-award|title=Prof Angela Casini wins 2019 Inorganic Chemistry Lectureship Award|last1=Medicinal|first1=Professor Angela Casini Chair of|last2=Chemistry|first2=Bioinorganic|website=Cardiff University|language=en|access-date=2019-08-26|last3=PGT|first3=Director of}}
= Selected publications =
Her publications include;
- {{Cite journal|title=Carbonic anhydrase inhibitors|last=Casini|first=Angela|date=2003|journal=Medicinal Research Reviews|volume=23|issue=2|pages=146–189|doi=10.1002/med.10025|pmid=12500287|s2cid=90349277|doi-access=free}}
- {{Cite journal|title=Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH|last=Casini|first=Angela|date=2004|journal=FEBS Letters|volume=577|issue=3|pages=439–445|doi=10.1016/j.febslet.2004.10.043|pmid=15556624|s2cid=37646843|doi-access=free}}
- {{Cite journal|title=Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition|last=Casini|first=Angela|date=2004|journal=Journal of Medicinal Chemistry|volume=47|issue=3|pages=550–557|doi=10.1021/jm030912m|pmid=14736236}}
Casini serves on the editorial board of the Journal of Biological Inorganic Chemistry and the Journal of Inorganic Biochemistry.
References
{{Authority control}}
{{DEFAULTSORT:Casini, Angela}}
Category:Italian women academics
Category:Italian women chemists
Category:University of Florence alumni
Category:University of Pisa alumni