Ann English
{{Short description|Canadian bioinorganic chemist}}
{{Infobox scientist
| name = Ann Marie English
| workplaces = Concordia University
| alma_mater = McGill University
University College Dublin
| thesis_title = Spectral Studies on Group VIB Metal Chalcocarbonyls
| thesis_url = https://escholarship.mcgill.ca/concern/theses/c534fr27s
| thesis_year = 1980
| doctoral_advisor = Ian S. Butler
| known_for = Bioinorganic Chemistry
Mass Spectrometry
}}
Ann Marie English is an Irish Canadian scientist in bioinorganic chemistry and redox biology, recognized for her contribution to chemistry in Canada.{{Cite web |title=Clara Benson Award |url=https://www.cheminst.ca/awards/csc/benson/ |access-date=2025-01-02 |website=The Chemical Institute of Canada |language=en-CA}}
Education
English received a BSc from University College Dubin in Ireland in 1971 and a PhD in Inorganic Chemistry from McGill University in Canada in 1980.{{Cite web |title=Ann English - Concordia University |url=https://www.concordia.ca/faculty/ann-english.html |access-date=2025-01-02 |website=www.concordia.ca |language=en}}
Career
After graduation, English did post-doctoral research at California Institute of Technology as a research fellow in chemistry.{{Cite web |date=September 1980 |title=INFORMATION FOR STUDENTS 1980-81 |url=https://campuspubs.library.caltech.edu/109/1/1980-1981.pdf |access-date=2025-01-01 |website=CALIFORNIA INSTITUTE OF TECHNOLOGY}} Under the direction of Harry B. Gray, she conducted research on electron transfer of copper proteins.{{Cite journal |last1=English |first1=Ann M. |last2=DeLaive |first2=Patricia J. |last3=Gray |first3=Harry B. |last4=Lum |first4=Vanessa R. |date=1982-02-01 |title=Metalloprotein electron-transfer mechanisms. Quenching of electronically excited tris(2,2'-bipyridine)ruthenium(II) by reduced blue copper proteins |url=https://pubs.acs.org/doi/abs/10.1021/ja00367a047 |journal=Journal of the American Chemical Society |volume=104 |issue=3 |pages=870–871 |doi=10.1021/ja00367a047 |bibcode=1982JAChS.104..870E |issn=0002-7863}} She began her academic career at Concordia University as assistant professor in 1982{{Cite web |title=A celebration of internal research awards - Concordia Journal - Concordia University - Montreal, Quebec, Canada |url=https://cjournal.concordia.ca/archives/20080320/a_celebration_of_internal_research_awards.php?print=1 |access-date=2025-01-02 |website=cjournal.concordia.ca}} and was promoted to full professor in 1994. Since 2018, she is Distinguished Professor Emerita and Honorary Concordia University Research Chair in the Department of Chemistry and Biochemistry at Concordia University.{{Cite web |title=Faculty members - Concordia University |url=https://www.concordia.ca/artsci/chemistry/about/faculty.html |access-date=2025-01-02 |website=www.concordia.ca |language=en}} She has mentored over 55 graduate students and 37 postdoctoral fellows and researchers.{{Cite web |last=Miller |first=Harry |date=2024-02-20 |title=Concordia's Ann English wins Lifetime Achievement Award for her seminal work in bioinorganic chemistry – Concordia University News |url=https://canadanewsmedia.ca/concordias-ann-english-wins-lifetime-achievement-award-for-her-seminal-work-in-bioinorganic-chemistry-concordia-university-news/ |access-date=2025-01-02 |website=Canada News Media |language=en-US}}
Her research field is in heme-protein chemistry and biochemistry,{{Cite journal |last1=Smulevich |first1=Giulietta |last2=Mauro |first2=J. Matthew |last3=Fishel |first3=Laurence A. |last4=English |first4=Ann M. |last5=Kraut |first5=Joseph |last6=Spiro |first6=Thomas G. |date=1988-07-01 |title=Heme pocket interactions in cytochrome c peroxidase studied by site-directed mutagenesis and resonance Raman spectroscopy |url=https://pubs.acs.org/doi/abs/10.1021/bi00415a014 |journal=Biochemistry |volume=27 |issue=15 |pages=5477–5485 |doi=10.1021/bi00415a014 |pmid=2846039 |issn=0006-2960}}{{Citation |last1=English |first1=Ann M. |title=Catalytic Structure–Function Relationships in Heme Peroxidases |date=1995-01-01 |volume=43 |pages=79–125 |editor-last=Sykes |editor-first=A. G. |url=https://linkinghub.elsevier.com/retrieve/pii/S0898883808601166 |access-date=2025-01-02 |publisher=Academic Press |doi=10.1016/s0898-8838(08)60116-6 |last2=Tsaprailis |first2=George|series=Advances in Inorganic Chemistry |isbn=978-0-12-023643-5 }}{{Cite journal |last1=Shadrina |first1=Maria S. |last2=Laterreur |first2=Julie |last3=Peslherbe |first3=Gilles H. |last4=English |first4=Ann M. |date=2024 |title=Hemoglobin's β-subunit is primed to synergize oxygen delivery with nitric oxide-mediated increased blood flow |url=https://www.worldscientific.com/doi/10.1142/S1088424624500305 |journal=Journal of Porphyrins and Phthalocyanines |volume=28 |issue=6 |pages=370–382 |doi=10.1142/S1088424624500305 |issn=1088-4246}} including the effects of metal-induced oxidation on aging at the cellular level.{{Cite web |title=Unlocking the secrets of aging - Concordia University |url=https://www.concordia.ca/cunews/main/stories/2014/02/05/unlocking-the-secretsofaging.html |access-date=2025-01-02 |website=www.concordia.ca |language=en}}{{Cite journal |last1=Martins |first1=Dorival |last2=English |first2=Ann M. |date=2012-11-01 |title=Cysteine 146 of CuZnSOD is Oxidized to Sulfonic Acid During Aging of Yeast: A Potential Mechanism Underlying Sporadic ALS Onset |url=https://linkinghub.elsevier.com/retrieve/pii/S0891584912014967 |journal=Free Radical Biology and Medicine |series=SFRBM's 19th Annual Meeting: Program and Abstracts |volume=53 |pages=S126 |doi=10.1016/j.freeradbiomed.2012.10.313 |issn=0891-5849}}{{Cite journal |last=English |first=Ann M |date=2010-01-01 |title=The Heme Peroxidase CCP is Released from Mitochondria during Chronological Aging of Yeast |url=https://linkinghub.elsevier.com/retrieve/pii/S0891584910007951 |journal=Free Radical Biology and Medicine |series=SFRBM's 17th Annual Meeting: Program and Abstracts |volume=49 |pages=S79 |doi=10.1016/j.freeradbiomed.2010.10.196 |issn=0891-5849}} She has published over 130 peer-reviewed journal articles and book chapters.{{Cite web |title=Ann English |url=https://scholar.google.com/citations?hl=en&user=VApIKmUAAAAJ&view_op=list_works |access-date=2025-01-02 |website=scholar.google.com}} With mass spectrometry being one of the techniques used in her research,{{Cite journal |last1=Jahangiri |first1=Soran |last2=Timerghazin |first2=Qadir K. |last3=Jiang |first3=Heng |last4=Peslherbe |first4=Gilles H. |last5=English |first5=Ann M. |date=2018-06-01 |title=Dramatic CC bond activation on protonation of the persistent nitroxyl radical TEMPO |url=https://linkinghub.elsevier.com/retrieve/pii/S1387380617302221 |journal=International Journal of Mass Spectrometry |series=Terry B. McMahon 70th Birthday Special Issue: Mass Spectrometry and its Application to the Physical Chemistry of Gaseous Ions |volume=429 |pages=182–188 |doi=10.1016/j.ijms.2017.08.007 |bibcode=2018IJMSp.429..182J |issn=1387-3806}}{{Cite journal |last1=Kathiresan |first1=Meena |last2=English |first2=Ann M. |date=2017-01-30 |title=LC-MS/MS suggests that hole hopping in cytochrome c peroxidase protects its heme from oxidative modification by excess H2O2 |journal=Chemical Science |language=en |volume=8 |issue=2 |pages=1152–1162 |doi=10.1039/C6SC03125K |issn=2041-6539 |pmc=5369544 |pmid=28451256}}{{Cite journal |last1=Papp |first1=Robert |last2=Ekiel |first2=Irena |last3=English |first3=Ann M |date=2003 |title=ESI-MS and FTIR studies of the interaction between the second PDZ domain of hPTP1E and target peptides |url=https://cdnsciencepub.com/doi/10.1139/o03-036 |journal=Biochemistry and Cell Biology |volume=81 |issue=2 |pages=71–80 |doi=10.1139/o03-036 |pmid=12870871 |issn=0829-8211}} she established the Centre for Biological Applications of Mass Spectrometry in 2003.
She was elected as Fellow of the Chemical Institute of Canada in 2014{{Cite web |title=CIC Fellows |url=https://www.cheminst.ca/wp-content/uploads/2023/04/Complete-List-of-CIC-Fellows-20241107.pdf |access-date=2025-01-01 |website=Chemical Institute of Canada}} and Fellow of the Royal Society of Canada Academy of Science in 2024.{{Cite web |title=Concordia celebrates a record year at the Royal Society of Canada - Concordia University |url=https://www.concordia.ca/news/stories/2024/09/03/concordia-celebrates-a-record-year-at-the-royal-society-of-canada.html |access-date=2025-01-02 |website=www.concordia.ca |language=en}}{{Cite web |title=ROYAL SOCIETY OF CANADA - CLASS OF 2024 |url=https://rsc-src.ca/sites/default/files/24_New%20Members_EN_1.pdf |access-date=2025-01-01 |website=ROYAL SOCIETY OF CANADA}}
Awards
- 2024 Eraldo Antonini Award, a Lifetime Achievement Award from the Society of Porphyrins and Phthalocyanines{{Cite web |title=Society of Porphyrins & Phthalocyanines |url=http://www.icpp-spp.org/general/awards.php |access-date=2025-01-02 |website=www.icpp-spp.org}}
- 2018 Fred P. Lossing Award from the Canadian Society for Mass Spectrometry{{Cite web |title=Lossing Award |url=https://www.csms-scsm.ca/fred-lossing-award |access-date=2025-01-02 |website=csms.clientwebdev.com}}
- 2018 Award for Graduate Mentoring from Concordia University{{Cite web |last1=Oct 12 |last2=Finalists |first2=2018 {{!}} Outstanding Graduate Mentorship |last3=Prizes |title=Finalist – 2018 Award for Outstanding Graduate Mentorship – Dr. Ann English {{!}} CAGS {{!}} ACES |url=https://cags.ca/prizes/2018-award-for-outstanding-graduate-mentorship-dr-ann-english/ |access-date=2025-01-02 |language=en-US}}
- 2017 Clara Benson Award from the Canadian Society for Chemistry
References
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Category:McGill University alumni
Category:Alumni of University College Dublin
Category:Fellows of the Royal Society of Canada
Category:Canadian women academics
Category:Bioinorganic chemists
Category:California Institute of Technology fellows
Category:Academic staff of Concordia University