Anne Spang
{{Use dmy dates|date=September 2023}}
{{short description|German biochemist, cell biologist, and professor}}
{{Infobox scientist
|name = Anne Spang
|image = Anne Spang 2015.jpg
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|caption = Spang in 2015
|birth_date = {{birth date and age|1967|11|29|df=yes}}
|birth_place = Wadern
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|nationality = German
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|field = Biochemist/Cell Biologist
|work_institutions = {{ubl|Darmstadt University of Applied Sciences|Pierre-and-Marie-Curie University|University of California, Berkeley|The Friedrich Miescher Laboratory of the MPG|Biozentrum University of Basel}}
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Anne Spang (born 29 November 1967 in Wadern){{cite web |url=https://memim.com/anne-spang.html|title=Bio Anne Spang |publisher=memim.com |date= |access-date=15 July 2020}} is a German Biochemist/Cell Biologist and Professor at the Biozentrum University of Basel, Switzerland.
Life
Anne Spang studied Chemical Engineering at the University of Applied Sciences in Darmstadt and Biochemistry at the University of Paris VI, France. She received her PhD in 1996 at the Max-Planck Institute of Biochemistry in Martinsried. She was then a postdoctoral fellow at the University of California, Berkeley, USA. From 1999 to 2006 she was an Independent Research Group Leader at the Friedrich Miescher Laboratory of the Max Planck Society in Tübingen.{{cite web |url=https://www.academia-net.org/profil/prof-dr-anne-spang/1134237 |title=Profile Prof. Dr. Anne Spang |publisher=academia-net.org |date= |access-date=11 July 2020}} Since 2005 Anne Spang has held the position of Professor of Biochemistry and Cell Biology at the Biozentrum University of Basel.{{cite web |url=https://www.biozentrum.unibas.ch/research/research-groups/research-groups-a-z/own-content/unit/research-group-anne-spang/spang-cv |title=Biozentrum Curriculum Vitae Anne Spang |publisher=biozentrum.unibas.ch |date= |access-date=19 September 2023}}
Work
Anne Spang investigates the basics of intracellular transport. Spang gained an international reputation through her discovery of the maturation process from early to late endosomes. In the nematode, Caenorhabditis elegans, she has identified the evolutionary conserved SAND-1 protein, which serves as the switch in Rab conversion during the maturation process.{{cite journal |title=Identification of the Switch in Early-to-Late Endosome Transition |year=2010 |publisher=cell.com |doi=10.1016/j.cell.2010.03.011 |last1=Poteryaev |first1=Dmitry |last2=Datta |first2=Sunando |last3=Ackema |first3=Karin |last4=Zerial |first4=Marino |last5=Spang |first5=Anne |journal=Cell |volume=141 |issue=3 |pages=497–508 |pmid=20434987 |s2cid=8430137 |doi-access=free }} In addition, her research has shown that ArfGAP proteins are important for the uptake of cargo into transport vesicles and that the small GTPase Arf1 and COPI components play a role in mRNA transport and mRNA metabolism.{{cite journal |url=https://bio.biologists.org/content/4/7/792|title=The ArfGAP2/3 Glo3 and ergosterol collaborate in transport of a subset of cargoes |year=2015 |publisher=bio.biologists.org |doi=10.1242/bio.011528 |access-date=11 July 2020|last1=Estrada |first1=Alejandro F. |last2=Muruganandam |first2=Gopinath |last3=Prescianotto-Baschong |first3=Cristina |last4=Spang |first4=Anne |journal=Biology Open |volume=4 |issue=7 |pages=792–802 |pmid=25964658 |pmc=4571087 }} Her research findings are significant for the understanding of many diseases which are based on the location of defects in protein and mRNA in the cell, such as cystic fibrosis and lysosomal storage disorders.{{cite journal |title=Defects in the Secretory Pathway and High Ca2+ Induce Multiple P-bodies |year=2010 |publisher=nih.gov|pmc=2912349 |last1=Kilchert |first1=C. |last2=Weidner |first2=J. |last3=Prescianotto-Baschong |first3=C. |last4=Spang |first4=A. |journal=Molecular Biology of the Cell |volume=21 |issue=15 |pages=2624–2638 |doi=10.1091/mbc.e10-02-0099 |pmid=20519435 }}
Awards and honors
- 2024: Elected member of the American Association for the Advancement of Sciences (AAAS) {{cite web |url=https://www.aaas.org/programs/fellows/2024-aaas-fellows |title=2024 AAAS Fellows |publisher=aaas.org |access-date=2025-03-31}}
- 2021: Elected member of the German National Academy of Sciences Leopoldina{{cite web |url=https://www.leopoldina.org/en/members/list-of-members/list-of-members/member/Member/show/anne-spang/ |title=List of members, Prof. Dr. Anne Spang |publisher=leopoldina.org |date= |access-date=19 September 2023}}
- 2010: Binder Innovation Prize{{cite web |url=https://www.pressebox.com/inactive/binder-central-services-gmbh-co-kg/BINDER-Innovation-Prize-2010/boxid/344347 |title=BINDER Innovation Prize 2010 |publisher=pressebox.com |date= |access-date=11 July 2020}}
- 2009: Elected member of the European Molecular Biology Organization (EMBO)
- 2005: Walther Flemming Medal of the German Society for Cell Biology {{cite web |url=https://loop.frontiersin.org/people/117716/bio |title=Bio Anne Spang|publisher=frontiersin.org|date= |access-date=11 July 2020}}
- 2002: EMBO Young Investigator[http://embc.embo.org/documents/embo_embc_annual_report_07.pdf EMBO Annual Report] {{webarchive |url=https://web.archive.org/web/20120611084551/http://embc.embo.org/documents/embo_embc_annual_report_07.pdf |date=11 June 2012 }} (PDF; 1,5 MB)
References
External links
- [http://www.biozentrum.unibas.ch/spang/ Research Group Anne Spang]
- [http://www.unibas.ch/ University of Basel]
- [https://web.archive.org/web/20130525073154/http://www.zellbiologie.de/en_startseite.phtml German Society for Cell Biology]
- [http://www.embo.org/ European Molecular Biology Organization (EMBO)]
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{{DEFAULTSORT:Spang, Anne}}
Category:21st-century German biologists
Category:German women biochemists
Category:University of California, Berkeley alumni
Category:Members of the European Molecular Biology Organization
Category:Biozentrum University of Basel