Anthony L. Komaroff

Anthony "Tony" Komaroff was raised in Los Angeles, California. He attended college at Stanford University and medical school at the University of Washington in Seattle.

Following medical school, he received training in internal medicine at Harvard Medical School and then joined the faculty.

Komaroff was the Director of the Division of General Medicine and Primary Care at Brigham & Women's Hospital, Boston MA, from 1982 to 1997, and built one of the world’s renowned academic general medicine units. From 1982 to 1987, he was the vice president for management systems of Brigham and Women's Hospital, with oversight of the Hospital's computer systems. From 1997 through January 2015, he served as Editor-in-Chief of the Harvard Health Publications Division (HHP) of Harvard Medical School, the division responsible for publishing all of the School's health information for the general public—books, newsletters, Internet content and doctors' office information. The information is published in multiple languages, in countries around the world [https://connects.catalyst.harvard.edu/Profiles/display/Person/66899].

Komaroff has published over 280 research articles and book chapters, and two books. His early publications cover the development of clinical algorithms,{{cite journal |pmid=4148936 |year=1974 |last1=Komaroff |first1=AL |last2=Black |first2=WL |last3=Flatley |first3=M |last4=Knopp |first4=RH |last5=Reiffen |first5=B |last6=Sherman |first6=H |title=Protocols for physician assistants. Management of diabetes and hypertension |volume=290 |issue=6 |pages=307–12 |doi=10.1056/NEJM197402072900605 |journal=The New England Journal of Medicine}}{{psc|date=May 2012}}{{cite journal |pmid=23495 |year=1978 |last1=Greenfield |first1=S |last2=Komaroff |first2=AL |last3=Pass |first3=TM |last4=Anderson |first4=H |last5=Nessim |first5=S |title=Efficiency and cost of primary care by nurses and physician assistants |volume=298 |issue=6 |pages=305–9 |doi=10.1056/NEJM197802092980604 |journal=The New England Journal of Medicine}}{{psc|date=May 2012}} cost-effectiveness analyses of primary care practices,{{cite journal |pmid=6804866 |year=1982 |last1=Berwick |first1=DM |last2=Komaroff |first2=AL |title=Cost effectiveness of lead screening |volume=306 |issue=23 |pages=1392–8 |doi=10.1056/NEJM198206103062304 |journal=The New England Journal of Medicine}}{{psc|date=May 2012}} and clinical research on common respiratory and urinary infections,.{{cite journal |doi=10.1126/science.6415813 |title=Serologic evidence of chlamydial and mycoplasmal pharyngitis in adults |year=1983 |last1=Komaroff |first1=AL. |last2=Aronson |first2=M. |last3=Pass |first3=T. |last4=Ervin |first4=C. |last5=Branch |first5=W. |last6=Schachter |first6=J |journal=Science |volume=222 |issue=4626 |pages=927–9 |pmid=6415813}}{{psc|date=May 2012}}{{cite journal |doi=10.1056/NEJM198008213030808 |title=The Dysuria-Pyuria Syndrome |year=1980 |last1=Komaroff |first1=AL. |last2=Friedland |first2=G |journal=New England Journal of Medicine |volume=303 |issue=8 |pages=452–4 |pmid=6893073}}{{psc|date=May 2012}} In recent decades, Dr. Komaroff’s research has focused on chronic fatigue syndrome{{cite journal|last1=Komaroff|first1=AL|title=Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Real Illness|journal=Annals of Internal Medicine|date=2015|volume=162|issue=12|pages=871–2|pmid=26075760|doi=10.7326/m15-0647|doi-access=free}}{{cite journal |last1=Komaroff |first1=AL |title=Inflammation correlates with symptoms in chronic fatigue syndrome. |journal=Proceedings of the National Academy of Sciences USA |year=2017 |volume=114 |issue=34 |pages=8914–6 |doi=10.1073/pnas.1712475114 |pmid=28811366 |pmc=5576849|doi-access=free }}{{cite journal |last1=Komaroff |first1=AL |title=Advances in understanding the pathophysiology of chronic fatigue syndrome. |journal=JAMA |year=2019 |volume=322 |issue=6 |pages=499–500 |doi=10.1001/jama.2019.8312|pmid=31276153|s2cid=195805355 }}{{cite journal|last1=Nagy-Szakal|first1=D|title=Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics.|journal=Scientific Reports|year=2018|volume=8|issue=1|page=10056|doi=10.1038/s41598-018-28477-9|pmid=29968805|pmc=6030047}}{{cite journal|last1=Komaroff|first1=AL|title=Insights from myalgic encephalomyelitis/chronic fatigue syndrome may help unravel the pathogenesis of post-acute COVID-19 syndrome. |journal=Trends in Molecular Medicine|year=2021|volume=27|issue=9 |pages=895–906|doi=10.1016/j.molmed.2021.06.002|s2cid=235354169 |doi-access=free|pmc=8180841}}{{cite journal|last1=Paul|first1=B|title=Redox imbalance links COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome. |journal=Proceedings of the National Academy of Sciences USA|year=2021|volume=118|issue=34|page= e2024358118|doi=10.1073/pnas.2024358118|pmid=34400495|pmc=8403932}}{{cite journal|last1=Komaroff|first1=AL|title=Will COVID-19 lead to myalgic encephalomyelitis/chronic fatigue syndrome? |journal=Frontiers in Medicine|year=2021|volume=7|page=606824|doi=10.3389/fmed.2020.606824|pmid=33537329 |pmc=7848220 |doi-access=free }} and also on human herpesvirus 6.{{cite journal|last1=Arbuckle|first1=JH|title=The latent human herpesvirus-6A genome specifically integrates in telomeres of human chromosomes in vivo and in vitro.|journal=Proceedings of the National Academy of Sciences USA|date=2010|volume=107|issue=12|pages=5563–8|doi=10.1073/pnas.0913586107|pmid=20212114|display-authors=etal|pmc=2851814|doi-access=free}}{{cite journal|last1=Komaroff|first1=AL|title=Human herpesviruses 6A and 6B in brain diseases: association versus causation. |journal=Clinical Microbiology Reviews|year=2020|volume=34|issue=1 |pages=e00143-20|doi=10.1128/CMR.00143-20|pmid=33177186 |pmc=7667666 }}{{cite journal|last1=Komaroff|first1=AL|title=Human herpesviruses 6A and 6B in reproductive diseases. |journal=Frontiers in Immunology|year=2021|volume=12|page=648945|doi=10.3389/fimmu.2021.648945|pmid=33841432 |pmc=8027340 |doi-access=free }}

Komaroff was the Editor in Chief of the best-selling book, the Harvard Medical School Family Health Guide;{{cite book|last1=Komaroff|first=Anthony L.|title=Harvard Medical School Family Health Guide|year=1999|publisher=Simon & Schuster}} is the founding editor of NEJM Journal Watch, a publication of the New England Journal of Medicine [https://www.jwatch.org]; is the editor-in-chief of the Harvard Health Letter, a newsletter from Harvard Medical School for the general public [https://www.health.harvard.edu/newsletters/harvard_health_letter]; and from 2011-December 2016 was the author of a daily newspaper column, Ask Doctor K, that was syndicated by United Media and appeared in over 400 newspapers in North America. In these publications, and in medical journals, he describes the latest developments in biological science and medical research to both practicing health professionals and the general public.{{cite journal|last1=Komaroff|first1=AL|title=The microbiome and risk for obesity and diabetes. |journal=JAMA |year=2017 |volume=317 |issue=4 |pages=355–6 |doi=10.1001/jama.2016.20099 |pmid=28006047|s2cid=5078210 }}{{cite journal |last1=Komaroff |first1=AL |title=Gene editing using CRISPR: why the excitement? |journal=JAMA |year=2017 |volume=318 |issue=8 |pages=699–700 |doi=10.1001/jama.2017.10159 |pmid=28796848}}{{cite journal|last1=Komaroff|first1=AL|title=Can infections cause Alzheimer disease? |journal=JAMA|year=2020|volume=324|issue=3 |pages=239–40|doi= 10.1001/jama.2020.4085|s2cid=219548603 }}{{cite journal|last1=Komaroff|first1=AL|title=Does sleep flush wastes from the brain? |journal=JAMA|year=2021|volume=325|issue=21 |pages=2153–4|doi=10.1001/jama.2021.5631|pmid=33999096 |s2cid=234747224 }}{{cite journal|last1=Komaroff|first1=AL|title=Breakthrough discovery in protein structure prediction and the promise of new treatments. |journal=JAMA|year=2021|volume=326|issue=14 |pages=1369–70|doi=10.1001/jama.2021.15728|pmid=34554183 |s2cid=237608592 }}

Finally, Komaroff also served as editor of the autobiographies of two biomedical scientists, Nobel Laureates Joseph E. Murray{{cite book|last1=Murray|first1=Joseph E.|title=Surgery of the Soul|year=2001|publisher=Science History Publications USA}} and Thomas H. Weller.{{cite book|last1=Weller|first=Thomas H.|title=Growing Pathogens in Tissue Cultures|year=2004|publisher=Science History Publications USA}}

Komaroff serves as the Distinguished Simcox-Clifford-Higby Professor of Medicine at Harvard Medical School and Senior Physician at Brigham and Women's Hospital in Boston [https://connects.catalyst.harvard.edu/Profiles/display/Person/66899].

• Elected a fellow of the American Association for the Advancement of Science, the American College of Physicians, and the Association for Health Services Research.
• Served on advisory committees for the United States Department of Health and Human Services, the Surgeon General of the United States, the Centers for Disease Control and Prevention, and the Institute of Medicine/National Academy of Sciences.
• Currently a member of the Scientific Advisory Board of the HHV-6 Foundation.

{{reflist}}

• [http://www.health.harvard.edu/ Harvard Health Publications, Harvard Medical School]
• [http://connects.catalyst.harvard.edu/profiles/profile/person/66899 Harvard Catalyst Profile]
• [http://www.hhv-6foundation.org/about-us/scientific-advisory-board HHV-6 Foundation Scientific Advisory Board]
• [http://www.askdoctork.com/ Ask Doctor K, Harvard Medical School]

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Category:American primary care physicians

Category:1941 births

Category:Living people