Anthony Zador
{{Short description|American neuroscientist}}
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| name = Anthony Zador
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| nationality = American
| fields = Neuroscience
| workplaces = Cold Spring Harbor Laboratory
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| education = B.A., University of California, Berkeley; MD-PhD, Yale University
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| doctoral_advisor = Christof Koch
| academic_advisors = Charles F. Stevens
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| known_for = Molecular approaches to connectomics; neural circuits underlying auditory decision making
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Anthony M. Zador is an American neuroscientist and the Alle Davis Harris Professor of Biology and Chair of Neuroscience at Cold Spring Harbor Laboratory.{{cite web|url=https://www.cshl.edu/Faculty/Anthony-Zador.html|title=CSHL Anthony Zador|publisher=Cold Spring Harbor Laboratory|accessdate=14 December 2016|archive-url=https://web.archive.org/web/20161220162203/https://www.cshl.edu/Faculty/Anthony-Zador.html|archive-date=20 December 2016|url-status=dead}} He is a co-founder, in 2004, of the Computational and Systems Neuroscience (COSYNE) conference, and of the NAISYS (Neuroscience to Artificially Intelligent Systems) meeting about the intersection of neuroscience and artificial intelligence. Dr. Zador's research has focused on understanding the circuits of the auditory cortex in rodents. More recently, he has pioneered a new approach to connectome mapping using the methods of molecular biology, which may dramatically decrease the cost and improve the speed of mapping neuronal circuits at the single cell level.{{cite web|url=https://blogs.scientificamerican.com/brainwaves/sequencing-the-connectome-will-dna-barcodes-and-a-sneaky-virus-change-the-way-scientists-map-the-brain/|title=Sequencing the Connectome: Will DNA Bar Codes and a Sneaky Virus Change the Way Scientists Map the Brain?|publisher=Scientific American|date=23 October 2012|accessdate=14 December 2016}}{{cite news|url=http://www.nature.com/nmeth/journal/v13/n11/full/nmeth.4064.html|title=Mapmaking with barcoded neurons|work=Nature Methods|date=31 October 2016|accessdate=14 December 2016}}
Biography
Anthony Zador received a B.A. at the UC, Berkeley and MD/PhD from Yale University, under the supervision of Tom Brown and Christof Koch at Caltech, focusing on machine learning and computational neuroscience. He carried out postdoctoral research in experimental neuroscience at the Salk Institute with Chuck Stevens before assuming a faculty position at Cold Spring Harbor Laboratory.
At CSHL, together with Zachary Mainen, he pioneered the use of quantitative behavioral paradigms in rodents to study perception and cognition.{{cite news|url=http://www.nature.com/news/2010/100519/full/465282a.html|title=Neuroscience: The rat pack|date=19 May 2010|work=Nature|accessdate=14 December 2016}} In 2012, Dr. Zador proposed a method harnessing advances in DNA sequencing to map neural circuits with much higher throughput than conventional microscopy-based approaches.{{cite journal|vauthors=Zador AM, Dubnau J, Oyibo HK, Zhan H, Cao G, Peikon ID|date=2012 |title=Sequencing the Connectome|journal=PLOS Biology|volume=10 |issue=10 |pages=e1001411 |doi=10.1371/journal.pbio.1001411|pmid=23109909 |pmc=3479097 |doi-access=free }} This method promises to reconstruct the connectivity matrices of entire brains with single cell resolution. So far, a variant of this approach has been applied to map the projection patterns single locus coeruleus neurons at the mesoscale,{{cite journal|vauthors=Kebschull JM, Garcia da Silva P, Reid AP, Peikon ID, Albeanu DF, Zador AM|date=2016 |title=High-Throughput Mapping of Single-Neuron Projections by Sequencing of Barcoded RNA|url= |journal=Neuron|volume=91|issue=5|pages=975–87|doi=10.1016/j.neuron.2016.07.036|pmid=27545715 |pmc=6640135 }} and also to the visual cortex.
Zador was recognized as a 2015 Foreign Policy Global Thinker.{{cite web|url=http://2015globalthinkers.foreignpolicy.com/#!gt-full-list|title=The Year of Changing Our Minds: The Leading Global Thinkers of 2015|last=|first=|publisher=Foreign Policy|date=}} He is also the winner of the Gill Transformative Investigator Award (2018). He is also an occasional columnist for the Observer, writing on the intersection of science, technology and policy.{{cite web|url=http://observer.com/2017/05/dna-research-government-golden-fleece-science-golden-egg/|title=Government's 'Golden Fleece' Is Now Humanity's Golden Goose|website=The New York Observer |date=19 May 2017}}
References
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External links
- [http://zadorlab.cshl.edu/ The Zador Laboratory Website]
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Category:American neuroscientists
Category:University of California, Berkeley alumni