Apocrine nevus

Apocrine nevi manifests as a persistent pedunculated or nodular skin-coloured axillary lump.{{cite journal | last1=Cordero | first1=Steven C | last2=Royer | first2=Michael C | last3=Rush | first3=Walter L | last4=Hallman | first4=James R | last5=Lupton | first5=George P | title=Pure Apocrine Nevus | journal=The American Journal of Dermatopathology | publisher=Ovid Technologies (Wolters Kluwer Health) | volume=34 | issue=3 | year=2012 | issn=0193-1091 | doi=10.1097/dad.0b013e31823adf0e | pages=305–309| pmid=22317889 }} Additionally, reports of them occurring on the face,{{cite journal | last1=MISAGO | first1=Noriyuki | last2=NARISAWA | first2=Yutaka | title=Syringocystadenoma papilliferum with extensive apocrine nevus | journal=The Journal of Dermatology | publisher=Wiley | volume=33 | issue=4 | year=2006 | issn=0385-2407 | doi=10.1111/j.1346-8138.2006.00073.x | pages=303–305| pmid=16674800 }}{{cite journal | last1=Schwartz | first1=Robert A. | last2=Rojas-Corona | first2=Rogelio | last3=Lambert | first3=W. Clark | title=The polymorphic apocrine nevus: A study of a unique tumor including carcinoembryonic antigen staining | journal=Journal of Surgical Oncology | publisher=Wiley | volume=26 | issue=3 | year=1984 | issn=0022-4790 | doi=10.1002/jso.2930260309 | pages=183–186| pmid=6738068 }} scalp,{{cite journal | last1=BURDEN | first1=PATRICIA A. | last2=GENTRY | first2=RICHARD H. | last3=FITZPATRICK | first3=JAMES E. | title=Piloleiomyoma Arising in an Organoid Nevus: A Case Report and Review of the Literature | journal=The Journal of Dermatologic Surgery and Oncology | publisher=Wiley | volume=13 | issue=11 | year=1987 | issn=0148-0812 | doi=10.1111/j.1524-4725.1987.tb02433.x | pages=1213–1222| pmid=3312332 }} chest,{{cite journal | last1=Kim | first1=Joong Hwan | last2=Hur | first2=Hoon | last3=Lee | first3=Chang Woo | last4=Kim | first4=Young Tae | title=Apocrine nevus | journal=Journal of the American Academy of Dermatology | publisher=Elsevier BV | volume=18 | issue=3 | year=1988 | issn=0190-9622 | doi=10.1016/s0190-9622(88)80291-3 | pages=579–581| pmid=3127435 }} and inguinal area have been made.{{cite journal | last1=Mori | first1=Osamu | last2=Hachisuka | first2=Hiroshi | last3=Sasai | first3=Yoichiro | title=APOCRINE NEVUS | journal=International Journal of Dermatology | volume=32 | issue=6 | date=1993 | issn=0011-9059 | doi=10.1111/j.1365-4362.1993.tb02821.x | pages=448–449| pmid=8320030 }} The majority of the time, apocrine nevi are asymptomatic, although some individuals describe minor pain, baldness, or in rare cases, leakage.{{cite journal | last1=Neill | first1=J. S. A. | last2=Park | first2=H. Kim | title=Apocrine nevus: light microscopic, immunohistochemical and ultrastructural studies of a case | journal=Journal of Cutaneous Pathology | publisher=Wiley | volume=20 | issue=1 | year=1993 | issn=0303-6987 | doi=10.1111/j.1600-0560.1993.tb01255.x | pages=79–83| pmid=8468422 }}{{cite journal | last1=Herrmann | first1=James J. | last2=Eramo | first2=Lynne R. | title=Congenital Apocrine Hamartoma: An Unusual Clinical Variant of Organoid Nevus with Apocrine Differentiation | journal=Pediatric Dermatology | publisher=Wiley | volume=12 | issue=3 | year=1995 | issn=0736-8046 | doi=10.1111/j.1525-1470.1995.tb00170.x | pages=248–251| pmid=7501558 }}

Apocrine nevi may be congenital. There have been reported associations with neurofibromatosis, epilepsy, and localized dermal hypoplasia, but these may be coincidental.{{cite journal | last1=Vakilzadeh | first1=Fereydoun | last2=Happle | first2=Rudolf | last3=Peters | first3=Peter | last4=Macher | first4=Egon | title=Fokale dermale hypoplasie mit apokrinen naevi und streifenförmiger anomalie der knochen | journal=Archives of Dermatological Research | volume=256 | issue=2 | date=1976 | issn=0340-3696 | doi=10.1007/BF00567364 | pages=189–195 | pmid=822789 | language=de}}

According to histopathology, apocrine nevi are made up of several mature apocrine sweat glands grouped in lobules that invade the dermis and/or hypodermis and cause normal skin structures to be displaced. There may be some cystic dilatation of the lumina in these glands.{{cite journal | last1=Kanitakis | first1=J. | last2=Kyamidis | first2=K. | last3=Toussinas | first3=A. | last4=Tsoïtis | first4=G. | title=Pure Apocrine Nevus: Immunohistochemical Study of a New Case and Literature Review | journal=Dermatology | volume=222 | issue=2 | date=2011 | issn=1018-8665 | doi=10.1159/000323000 | pages=97–101| pmid=21212656 }}

• Eccrine nevus
• Seborrheic keratosis
• List of cutaneous conditions

{{reflist}}

• {{cite journal | last1=Ando | first1=Ko-ichi | last2=Hashikawa | first2=Yuko | last3=Nakashima | first3=Mikio | last4=Nakayama | first4=Atsuo | last5=Ohashi | first5=Masaru | title=Pure Apocrine Nevus A Study of Light-Microscopic and Immunohistochemical Features of a Rare Tumor | journal=The American Journal of Dermatopathology | publisher=Ovid Technologies (Wolters Kluwer Health) | volume=13 | issue=1 | year=1991 | issn=0193-1091 | doi=10.1097/00000372-199102000-00012 | pages=71–76 | pmid=2003651 | ref=none}}
• {{cite journal | last1=Numata | first1=Yukikazu | last2=Okuyama | first2=Ryuhei | last3=Terui | first3=Tadashi | last4=Sasai | first4=Shu | last5=Tagami | first5=Hachiro | last6=Aiba | first6=Setsuya | title=Apocrine Nevus in Abdominal Skin | journal=Dermatology | publisher=S. Karger AG | volume=213 | issue=1 | year=2006 | issn=1018-8665 | doi=10.1159/000092839 | pages=46–47 | pmid=16778428 | ref=none}}

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Category:Epidermal nevi, neoplasms, and cysts

Category:Apocrine