Aprindine

{{Short description|Antiarrhythmic drug}}

{{cs1 config|name-list-style=vanc|display-authors=6}}

{{Drugbox

| verifiedrevid = 44339541

| IUPAC_name = {3-[2,3-dihydro-1H-inden-2-yl(phenyl)amino]propyl}diethylamine

| image = Aprindine.svg

| image_class = skin-invert-image

| tradename =

| Drugs.com = {{drugs.com|international|aprindine}}

| pregnancy_AU =

| pregnancy_US =

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| legal_UK =

| legal_US =

| legal_status =

| routes_of_administration =

| bioavailability =

| protein_bound =

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| CAS_number_Ref = {{cascite|correct|??}}

| CAS_number = 37640-71-4

| ATC_prefix = C01

| ATC_suffix = BB04

| PubChem = 2218

| DrugBank_Ref = {{drugbankcite|correct|drugbank}}

| DrugBank = DB01429

| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}

| ChemSpiderID = 2132

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = 5Y48085P9Q

| KEGG_Ref = {{keggcite|correct|kegg}}

| KEGG = D02969

| ChEMBL_Ref = {{ebicite|correct|EBI}}

| ChEMBL = 1213033

| C=22 | H=30

| N=2

| smiles = c1cccc3c1CC(N(c2ccccc2)CCCN(CC)CC)C3

| StdInChI_Ref = {{stdinchicite|correct|chemspider}}

| StdInChI = 1S/C22H30N2/c1-3-23(4-2)15-10-16-24(21-13-6-5-7-14-21)22-17-19-11-8-9-12-20(19)18-22/h5-9,11-14,22H,3-4,10,15-18H2,1-2H3

| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}

| StdInChIKey = NZLBHDRPUJLHCE-UHFFFAOYSA-N

}}

Aprindine is a Class 1b antiarrhythmic agent{{Cite web|url=https://www.whocc.no/atc_ddd_index/?code=C01BB&showdescription=yes|title=WHOCC - ATC/DDD Index | publisher = WHO Collaborating Centre for Drug Statistics Methodology |access-date=2018-03-01}} and has antiarrhythmic properties similar to lidocaine.{{cite journal | vauthors = Stoel I, Hagemeijer F | title = Aprindine: a review | journal = European Heart Journal | volume = 1 | issue = 2 | pages = 147–56 | date = April 1980 | pmid = 7026249 | doi = 10.1093/oxfordjournals.eurheartj.a061109 }}

References