Archain 1

{{Short description|Protein-coding gene in the species Homo sapiens}}

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Archain 1 is a protein that in humans is encoded by the ARCN1 gene.

{{cite web

| title = Entrez Gene: Archain 1

| url = https://www.ncbi.nlm.nih.gov/gene/372

| access-date = 2016-06-22

}}

Function

This gene maps in a region, which include the mixed lineage leukemia and Friend leukemia virus integration 1 genes, where multiple disease-associated chromosome translocations occur. It is an intracellular protein. Archain sequences are well conserved among eukaryotes and this protein may play a fundamental role in eukaryotic cell biology. It has similarities to heat shock proteins and clathrin-associated proteins, and may be involved in vesicle structure or vesicle trafficking.

References

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Further reading

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  • {{cite journal |vauthors=Deng K, Gao F, Zheng P, Gong W, Sun Z |title=Crystallization and preliminary X-ray analysis of the C-terminal domain of δ-COP, a medium-sized subunit of the COPI complex involved in membrane trafficking |journal=Acta Crystallographica Section F |volume=68 |issue=Pt 7 |pages=829–31 |year=2012 |pmid=22750876 |pmc=3388933 |doi=10.1107/S1744309112022798 }}

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