Archain 1
Function
This gene maps in a region, which include the mixed lineage leukemia and Friend leukemia virus integration 1 genes, where multiple disease-associated chromosome translocations occur. It is an intracellular protein. Archain sequences are well conserved among eukaryotes and this protein may play a fundamental role in eukaryotic cell biology. It has similarities to heat shock proteins and clathrin-associated proteins, and may be involved in vesicle structure or vesicle trafficking.
References
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Further reading
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- {{cite journal |vauthors=Deng K, Gao F, Zheng P, Gong W, Sun Z |title=Crystallization and preliminary X-ray analysis of the C-terminal domain of δ-COP, a medium-sized subunit of the COPI complex involved in membrane trafficking |journal=Acta Crystallographica Section F |volume=68 |issue=Pt 7 |pages=829–31 |year=2012 |pmid=22750876 |pmc=3388933 |doi=10.1107/S1744309112022798 }}
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