Aristolochia clematitis

It was formerly used as a medicinal plant, though it is now thought to be the cause of thousands of kidney failure cases in Romania, Bulgaria, Serbia, Bosnia and Herzegovina and Croatia. The initial hypothesis that seeds from the plant were unintentionally consumed through contaminated flour has come to be questioned.{{Cite journal | last1 = Grollman | first1 = A. P. | last2 = Shibutani | first2 = S. | last3 = Moriya | first3 = M. | last4 = Miller | first4 = F. | last5 = Wu | first5 = L. | last6 = Moll | first6 = U. | last7 = Suzuki | first7 = N. | last8 = Fernandes | first8 = A. | last9 = Rosenquist | first9 = T. | last10 = Medverec | doi = 10.1073/pnas.0701248104 | first10 = Z. | last11 = Jakovina | first11 = K. | last12 = Brdar | first12 = B. | last13 = Slade | first13 = N. | last14 = Turesky | first14 = R. J. | last15 = Goodenough | first15 = A. K. | last16 = Rieger | first16 = R. | last17 = Vukelic | first17 = M. | last18 = Jelakovic | first18 = B. | title = Aristolochic acid and the etiology of endemic (Balkan) nephropathy | journal = Proceedings of the National Academy of Sciences | volume = 104 | issue = 29 | pages = 12129–34 | year = 2007 | pmid = 17620607| pmc = 1913550| bibcode = 2007PNAS..10412129G | doi-access = free }}Batuman, Elif. "Poisoned Land." The New Yorker. August 12 & 19, 2013: 42-47. Print. Urinary tract malignancies among those who have consumed the plant are also reported.{{Cite journal | last1 = Broe | first1 = M. E. D. | title = Chinese herbs nephropathy and Balkan endemic nephropathy: Toward a single entity, aristolochic acid nephropathy | doi = 10.1038/ki.2011.428 | journal = Kidney International | volume = 81 | issue = 6 | pages = 513–515 | year = 2012 | pmid = 22373701| doi-access = free }} The link between kidney failure and aristolochic acid, which the plant contains, was discovered after a clinic for obesity in Belgium used herbal products based on another plant of the same genus as a diuretic. After a few months, some of the patients experienced kidney failure.{{Cite journal | last1 = Vanherweghem | first1 = J. L. | last2 = Tielemans | first2 = C. | last3 = Abramowicz | first3 = D. | last4 = Depierreux | first4 = M. | last5 = Vanhaelen-Fastre | first5 = R. | last6 = Vanhaelen | first6 = M. | last7 = Dratwa | first7 = M. | last8 = Richard | first8 = C. | last9 = Vandervelde | first9 = D. | last10 = Verbeelen | doi = 10.1016/0140-6736(93)92984-2 | first10 = D. | last11 = Jadoul | first11 = M. | title = Rapidly progressive interstitial renal fibrosis in young women: Association with slimming regimen including Chinese herbs | journal = The Lancet | volume = 341 | issue = 8842 | pages = 387–91 | year = 1993 | pmid = 8094166| s2cid = 32428737 }}

• Balkan nephropathy

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clematitis

Category:Medicinal plants of Europe

Category:Plants described in 1753

Category:Taxa named by Carl Linnaeus

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