Aryl-aldehyde dehydrogenase (NADP+)
{{infobox enzyme
| Name = aryl-aldehyde dehydrogenase (NADP+)
| EC_number = 1.2.1.30
| CAS_number = 9074-94-6
| GO_code = 0047683
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In enzymology, an aryl-aldehyde dehydrogenase (NADP+) ({{EC number|1.2.1.30}}) is an enzyme that catalyzes the chemical reaction
:an aromatic aldehyde + NADP+ + AMP + diphosphate + H2O an aromatic acid + NADPH + H+ + ATP
The 5 substrates of this enzyme are aromatic aldehyde, NADP+, AMP, diphosphate, and H2O, whereas its 4 products are aromatic acid, NADPH, H+, and ATP.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is aryl-aldehyde:NADP+ oxidoreductase (ATP-forming). Other names in common use include aromatic acid reductase, and aryl-aldehyde dehydrogenase (NADP+).
References
{{reflist|1}}
- {{cite journal | author = Gross GG | date = 1972 | title = Formation and reduction of intermediate acyladenylate by aryl-aldehyde. NADP oxidoreductase from Neurospora crassa | journal = Eur. J. Biochem. | volume = 31 | pages = 585–92 | pmid = 4405494 | doi = 10.1111/j.1432-1033.1972.tb02569.x | issue = 3 | doi-access = free }}
- {{cite journal |vauthors=Gross GG, Zenk MH | date = 1969 | title = [Reduction of aromatic acids to aldehydes and alcohols in the cell-free system. 1. Purification and properties of aryl-aldehyde: NADP-oxidoreductase from Neurospora crassa] | journal = Eur. J. Biochem. | volume = 8 | pages = 413–9 | pmid = 4389863 | issue = 3 | doi = 10.1111/j.1432-1033.1969.tb00543.x }}
{{Aldehyde/Oxo oxidoreductases}}
{{Enzymes}}
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Category:NADPH-dependent enzymes
Category:Enzymes of unknown structure
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