Aspirin/meprobamate
{{Short description|Combination drug}}
{{refimprove|date=June 2016}}
{{Infobox drug
| drug_name =
| type = combo
| component1 = Aspirin
| class1 = NSAID
| component2 = Meprobamate
| class2 = Anxiolytic
| pronounce =
| tradename = Equagesic
| Drugs.com = {{Drugs.com|cons|equagesic}}
| MedlinePlus =
| pregnancy_AU =
| pregnancy_US = X
| pregnancy_category=
| legal_AU =
| legal_AU_comment =
| legal_CA =
| legal_UK =
| legal_US = Rx-only
| legal_UN =
| legal_NZ =
| legal_status =
| routes_of_administration = Oral
| CAS_number = 8056-21-1
| ATCvet =
| ATC_prefix = N05
| ATC_suffix = BC51
| PubChem =
| DrugBank =
}}
Aspirin/meprobamate (trade name Equagesic {{IPAc-en|ˌ|ɛ|k|w|ə|ˈ|dʒ|iː|z|ɪ|k}}) is a combination drug indicated for short-term pain treatment accompanied by tension or anxiety in patients with musculoskeletal disorders or tension headache.
Adverse effects
{{See also|Aspirin#Adverse effects|Meprobamate#Adverse effects}}
Combinations
There also appears to be a combination with ethoheptazine, an opioid analgesic.{{cite web | url = http://www2.netdoctor.co.uk/medicines/showpreparation.asp?id=945 | work = NetDoctor.co.uk | title = Equagesic | quote = Discontinued in the UK – March 2002 | archive-url = https://web.archive.org/web/20070927173657/http://www2.netdoctor.co.uk/medicines/showpreparation.asp?id=945 | archive-date= 27 September 2007 }}
Problems
Equagesic was discontinued in the United States, because of its possible toxic effects, specifically of meprobamate.{{Cite web|title=Meprobamate Tablets 400mg – Summary of Product Characteristics (SmPC) – (emc)|url=https://www.medicines.org.uk/emc/product/5415/smpc#gref|access-date=2021-08-09|website=www.medicines.org.uk}}{{medcn|date=August 2021}} It was credited with the sudden death of actor Bruce Lee in 1973. Lee suffered a fatal hypersensitive reaction to one of the prescription drug's ingredients while working in Hong Kong.{{Cite web| vauthors = Chang R |title=Bruce Lee: The Mystery Surrounding the Martial Artist's Death|url=https://www.biography.com/news/bruce-lee-death-mystery|access-date=2021-08-09|website=Biography|date=7 June 2020 |language=en-us}}{{Cite web|title=Bruce Lee|url=https://brucelee.com/bruce-lee|access-date=2021-08-09|website=Bruce Lee|language=en-US}}