Autologous patient-specific tumor antigen response

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{{Infobox medical intervention

| name = Autologous patient-specific tumor antigen response

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| specialty = oncology

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Autologous patient-specific tumor antigen response (apSTAR) technology is a new cancer treatment procedure being developed by IMULAN BioTherapeutics, LLC and [http://www.VetCancer.com Veterinary Cancer Therapeutics, LLC] for comparative oncology.

Also known as laser-assisted immunotherapy, apSTAR is an experimental cancer treatment for solid tumors that uses an autologous vaccine-like approach to stimulate immune responses. Specifically, laser-assisted immunotherapy combines laser-induced in situ tumor devitalization with an immunoadjuvant for local immunostimulation.{{cite journal |vauthors=Song S, Zhou F, Nordquist RE, Carubelli R, Liu H, Chen WR |title=Glycated chitosan as a new non-toxic immunological stimulant |journal=Immunopharmacol Immunotoxicol |volume=31 |issue=2 |pages=202–8 |date=June 2009 |pmid=19514994 |pmc=6005360 |doi=10.1080/08923970802629593 }}{{cite journal |vauthors=Chen WR, Huang Z, Korbelik M, Nordquist RE, Liu H |title=Photoimmunotherapy for cancer treatment |journal=J. Environ. Pathol. Toxicol. Oncol. |volume=25 |issue=1–2 |pages=281–91 |year=2006 |pmid=16566724 |doi=10.1615/jenvironpatholtoxicoloncol.v25.i1-2.180}}{{cite journal |vauthors=Chen WR, Korbelik M, Bartels KE, Liu H, Sun J, Nordquist RE |title=Enhancement of laser cancer treatment by a chitosan-derived immunoadjuvant |journal=Photochem. Photobiol. |volume=81 |issue=1 |pages=190–5 |year=2005 |pmid=15535737 |doi=10.1562/2004-07-20-RA-236 }}{{cite journal |vauthors=Chen WR, Carubelli R, Liu H, Nordquist RE |title=Laser immunotherapy: a novel treatment modality for metastatic tumors |journal=Mol. Biotechnol. |volume=25 |issue=1 |pages=37–44 |date=September 2003 |pmid=13679633 |doi=10.1385/MB:25:1:37 |s2cid=26210086 }}{{cite journal |vauthors=Chen WR, Liu H, Ritchey JW, Bartels KE, Lucroy MD, Nordquist RE |title=Effect of different components of laser immunotherapy in treatment of metastatic tumors in rats |journal=Cancer Res. |volume=62 |issue=15 |pages=4295–9 |date=August 2002 |pmid=12154032 |url=http://cancerres.aacrjournals.org/cgi/pmidlookup?view=long&pmid=12154032}}{{cite journal |vauthors=Chen WR, Zhu WG, Dynlacht JR, Liu H, Nordquist RE |title=Long-term tumor resistance induced by laser photo-immunotherapy |journal=Int. J. Cancer |volume=81 |issue=5 |pages=808–12 |date=May 1999 |pmid=10328237 |doi=10.1002/(SICI)1097-0215(19990531)81:5<808::AID-IJC23>3.0.CO;2-J|doi-access=free }}{{cite journal |vauthors=Chen WR, Adams RL, Carubelli R, Nordquist RE |title=Laser-photosensitizer assisted immunotherapy: a novel modality for cancer treatment |journal=Cancer Lett. |volume=115 |issue=1 |pages=25–30 |date=May 1997 |pmid=9097975 |doi=10.1016/S0304-3835(97)04707-1}}

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