Banti's syndrome
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Banti's syndrome (also known as Banti's disease), named for Guido Banti,{{WhoNamedIt|synd|475}} is a chronic congestive enlargement of the spleen{{DorlandsDict|nine/000950693|Banti disease}} resulting in premature destruction of the red blood cells by the spleen.
Presentation
Enlargement of spleen, ascites, jaundice, and the result of destruction of various blood cells by spleen – anemia, leukopenia, thrombocytopenia, gastrointestinal bleeding – may constitute the presenting symptoms.{{cn|date=March 2021}}
Pathogenesis
The basic pathology is some kind of obstructive pathology in the portal, hepatic or splenic vein that causes obstruction of venous blood flow from the spleen towards the heart. The cause of such obstruction may be abnormalities present at birth (congenital) of certain veins, blood clots, or various underlying disorders causing inflammation and obstruction of veins (vascular obstruction) of the liver.{{cn|date=March 2021}}
Diagnosis
Banti's syndrome can be diagnosed by clinical evaluation and specialized tests, particularly imaging techniques such as splenic venography and MRI.{{Cite web|url=https://rarediseases.org/rare-diseases/bantis-syndrome/|title=Banti's Syndrome|website=NORD (National Organization for Rare Disorders)|language=en-US|access-date=2019-04-19}}
Treatment
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Notes
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External links
- [https://archive.today/20130731191918/http://www.pubmedcentral.com/articlerender.fcgi?artid=424896 1937 article in The Journal of Clinical Investigation]
{{Lymphatic organ disease}}
Category:Lymphatic organ diseases