Benzilone
{{Short description|Chemical compound}}
{{Distinguish|Benzylone}}
{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 443417081
| IUPAC_name = 1,1-diethyl-3-(2-hydroxy-2,2-diphenylacetoxy)pyrrolidinium
| image = Benzilone.png
| tradename =
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
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| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 16175-92-1
| CAS_supplemental =
{{CAS|1050-48-2}} (bromide)
| ATC_prefix = A03
| ATC_suffix = AB01
| PubChem = 66248
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 2106061
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank =
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = GY56LQX77B
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 59632
| smiles = O=C(OC1CC[N+](CC)(CC)C1)C(O)(c2ccccc2)c3ccccc3
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI = 1S/C22H28NO3/c1-3-23(4-2)16-15-20(17-23)26-21(24)22(25,18-11-7-5-8-12-18)19-13-9-6-10-14-19/h5-14,20,25H,3-4,15-17H2,1-2H3/q+1
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = ZKCWITXZGWUJAV-UHFFFAOYSA-N
| C=22 | H=28 | N=1 | O=3
}}
Benzilone is an antimuscarinic drug.{{cite web | work = KEGG database | url = http://www.genome.jp/dbget-bin/www_bget?drug+D03088 |title = Benzilone | access-date = 9 May 2015 }}{{cite journal | vauthors = Schwartz TW, Stenquist B, Olbe L, Stadil F | title = Synchronous oscillations in the basal secretion of pancreatic-polypeptide and gastric acid. Depression by cholinergic blockade of pancreatic-polypeptide concentrations in plasma | journal = Gastroenterology | volume = 76 | issue = 1 | pages = 14–9 | date = January 1979 | pmid = 758136 | doi = 10.1016/s0016-5085(79)80121-3 | quote = Benzilonium bromide (Parke, Davis & Co., Detroit Mich.) is a quarternary [sic] antimuscarinic agent with minimal passage of the blood-brain barrier. | doi-access = free }}
References
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{{Drugs for functional gastrointestinal disorders}}
{{Muscarinic acetylcholine receptor modulators}}
Category:Muscarinic antagonists
Category:Quaternary ammonium compounds
{{gastrointestinal-drug-stub}}