Benzyl salicylate
{{chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 477371698
| ImageFile = Benzyl salicylate wide.svg
| ImageSize = 220px
| ImageAlt = Structural formula of benzyl salicylate
| ImageFile1 = Benzyl salicylate 3D ball.png
| ImageSize1 = 220px
| ImageAlt1 = Ball-and-stick model of the benzyl salicylate molecule
| PIN = Benzyl 2-hydroxybenzoate
| OtherNames =
|Section1={{Chembox Identifiers
| CASNo_Ref = {{cascite|correct|CAS}}
| CASNo = 118-58-1
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = WAO5MNK9TU
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 460124
| PubChem = 8363
| SMILES = O=C(OCc1ccccc1)c2ccccc2O
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 8060
| InChI = 1/C14H12O3/c15-13-9-5-4-8-12(13)14(16)17-10-11-6-2-1-3-7-11/h1-9,15H,10H2
| InChIKey = ZCTQGTTXIYCGGC-UHFFFAOYAC
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C14H12O3/c15-13-9-5-4-8-12(13)14(16)17-10-11-6-2-1-3-7-11/h1-9,15H,10H2
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = ZCTQGTTXIYCGGC-UHFFFAOYSA-N
}}
|Section2={{Chembox Properties
| C=14 | H=12 | O=3
| Appearance = Colorless liquid
| Density = 1.17 g/cm3
| MeltingPtC = 24 to 25
| BoilingPtC = 318
| Solubility =
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|Section3={{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt =
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Benzyl salicylate is a salicylic acid benzyl ester, a chemical compound most frequently used in cosmetics as a fragrance additive or UV light absorber. It appears as an almost colorless liquid with a mild odor described as "very faint, sweet-floral, slightly balsamic" by some, while others smell nothing at all. There is debate whether the odour is caused solely by impurities or a genetic predisposition.Steffen Arctander: Perfume and Flavor Chemicals. {{ISBN|0-931710-37-5}} It occurs naturally in a variety of plants and plant extracts and is widely used in blends of fragrance materials.{{cite web | url = http://www.thegoodscentscompany.com/data/rw1001791.html | title = Benzyl salicylate | publisher = The Good Scents Company}}
There is some evidence that people may become sensitized to this material{{cite journal | url = http://www.rifm.org/doc/Food%20%26%20Chem%20Tox%20RIFM%20Spec%20Suppl%20122007.pdf | journal = Food and Chemical Toxicology | volume = 45 | issue = Supplement 1 | year = 2007 | title = Toxicologic and Dermatologic Assessments for Three Groups of Fragrance Ingredients: 1) Related Esters and Alcohols of Cinnamic Acid and Cinnamic Alcohol, 2) Ionones, 3) Salicylates | doi = 10.1016/j.fct.2007.09.087 | pmid = 18035463 | pages = S1-23 | last1 = Belsito | first1 = D | last2 = Bickers | first2 = D | last3 = Bruze | first3 = M | last4 = Calow | first4 = P | last5 = Greim | first5 = H | last6 = Hanifin | first6 = JM | last7 = Rogers | first7 = AE | last8 = Saurat | first8 = JH | last9 = Sipes | first9 = IG | last10 = Tagami | first10 = H | access-date = 2012-04-05 | archive-date = 2021-01-12 | archive-url = https://web.archive.org/web/20210112105000/https://www.rifm.org/doc/Food%20%26%20Chem%20Tox%20RIFM%20Spec%20Suppl%20122007.pdf | url-status = dead }} and as a result, there is a restriction standard concerning the use of this material in fragrances by the International Fragrance Association.{{cite web | url = http://www.ifraorg.org/en-us/standards_restricted/s3/p2 | title = Standards Restricted | publisher = International Fragrance Association | url-status = dead | archiveurl = https://web.archive.org/web/20120104024607/http://www.ifraorg.org/en-us/standards_restricted/s3/p2 | archivedate = 2012-01-04 }}
It is used as a solvent for crystalline synthetic musks and as a component and fixative in floral perfumes such as carnation, jasmine, lilac, and wallflower.An Introduction to Perfumery by Curtis & Williams 2nd Edition, 2009, {{ISBN|978-0-9608752-8-3}}, {{ISBN|978-1-870228-24-4}}
See also
References
{{Reflist}}
External links
- {{CPID|id=3469}}
{{Salicylates}}
{{DEFAULTSORT:Benzyl Salicylate}}