Biapenem

{{Short description|Chemical compound}}

{{Drugbox

| verifiedrevid = 443422119

| IUPAC_name = (4R,5S,6S)-3-(6,7-dihydro-5H- pyrazolo[1,2-a] [1,2,4]triazol-8- ium-6-ylsulfanyl)- 6-(1-hydroxyethyl)- 4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2- ene-2-carboxylate

| image = Biapenem.svg

| tradename = Omegacin

| Drugs.com = {{drugs.com|international|biapenem}}

| pregnancy_AU =

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| legal_AU =

| legal_CA =

| legal_UK =

| legal_US =

| legal_status = Rx-only

| routes_of_administration = IV

| bioavailability =

| protein_bound =

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| CAS_number_Ref = {{cascite|correct|??}}

| CAS_number = 120410-24-4

| CAS_supplemental =

| ATC_prefix = J01

| ATC_suffix = DH05

| ATC_supplemental =

| PubChem = 71339

| DrugBank_Ref = {{drugbankcite|correct|drugbank}}

| DrugBank =

| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}

| ChemSpiderID = 64442

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = YR5U3L9ZH1

| ChEBI_Ref = {{ebicite|correct|EBI}}

| ChEBI = 3089

| ChEMBL_Ref = {{ebicite|correct|EBI}}

| ChEMBL = 285347

| chemical_formula =

| C=15 | H=18 | N=4 | O=4 | S=1

| smiles = CC1C2C(C(=O)N2C(=C1SC3CN4C=NC=[N+]4C3)C(=O)[O-])C(C)O

| StdInChI_Ref = {{stdinchicite|correct|chemspider}}

| StdInChI = 1S/C15H18N4O4S/c1-7-11-10(8(2)20)14(21)19(11)12(15(22)23)13(7)24-9-3-17-5-16-6-18(17)4-9/h5-11,20H,3-4H2,1-2H3/t7-,8-,10-,11-/m1/s1

| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}

| StdInChIKey = MRMBZHPJVKCOMA-YJFSRANCSA-N

}}

Biapenem (INN) is a carbapenem antibiotic. It has in vitro activity against anaerobes.{{cite journal |vauthors=Aldridge KE, Morice N, Schiro DD |title=In vitro activity of biapenem (L-627), a new carbapenem, against anaerobes |journal=Antimicrob. Agents Chemother. |volume=38 |issue=4 |pages=889–93 |date=April 1994 |pmid=8031067 |pmc=284564 |doi= 10.1128/aac.38.4.889|url=}}

1-β-methyl-carbapenem antibiotic. Approved in Japan in 2001.

References

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